anti-TATA Box Binding Protein (TBP) Antikörper

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. Zusätzlich bieten wir Ihnen TBP Proteine (35) und TBP Kits (25) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
TBP 6908 P20226
TBP 21374 P29037
TBP 117526  
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Top anti-TBP Antikörper auf antikoerper-online.de

Showing 10 out of 143 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-TBP Antibody Titration: </b>2.5ug/ml<br><b>Positive Control: </b>Human Placenta 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$229.00
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of extracts from 293 cells, using TBP Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert IF, IHC (p), WB Western blot analysis of TBP antibody (C-term) (ABIN390630) in HL60 cell line lysates (35 µg/lane). TBP (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human testis tissue reacted with TBP Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert FACS, IF, IHC (p), WB Western blot analysis of TBP antibody (Center) (ABIN390631) in HL60 cell line lysates (35 µg/lane). TBP (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human testis tissue reacted with TBP Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Huhn Kaninchen Unkonjugiert IC, IF, IHC, WB Immunofluorescent analysis of TBP staining in HEK293T cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a hidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of TBP staining in human prostate cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert EIA, WB Western blot analysis of TBP antibody (C-term) in HL60 cell line lysates (35ug/lane). TBP (arrow) was detected using the purified Pab. 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Maus Unkonjugiert ICC, IF, IP, IHC, WB Tbp antibody (mAb) tested by immunofluorescence. Formaldehyde fixed HeLa cells stained with Tbp antibody at a 0.5 µg/ml dilution. 100 μg Anmelden zum Anzeigen 1 bis 2 Tage
$495.83
Details
Fledermaus Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$493.17
Details
Fledermaus Ziege Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$610.50
Details
Fledermaus Ziege Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$610.50
Details

TBP Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-TBP Antikörper

  1. Human Monoclonal TBP Primary Antibody für WB - ABIN1882281 : Hoffman, Sinn, Yamamoto, Wang, Roy, Horikoshi, Roeder: Highly conserved core domain and unique N terminus with presumptive regulatory motifs in a human TATA factor (TFIID). in Nature 1990 (PubMed)
    Show all 3 Pubmed References

  2. Human Monoclonal TBP Primary Antibody für WB - ABIN1882282 : Peterson, Tanese, Pugh, Tjian: Functional domains and upstream activation properties of cloned human TATA binding protein. in Science (New York, N.Y.) 1990 (PubMed)
    Show all 3 Pubmed References

  3. Human Monoclonal TBP Primary Antibody für ICC, IF - ABIN2668630 : Brou, Chaudhary, Davidson, Lutz, Wu, Egly, Tora, Chambon: Distinct TFIID complexes mediate the effect of different transcriptional activators. in The EMBO journal 1993 (PubMed)
    Show all 3 Pubmed References

  4. Cow (Bovine) Polyclonal TBP Primary Antibody für WB - ABIN2792684 : Reid, van Roon-Mom, Wood, Rees, Owen, Faull, Dragunow, Snell: TBP, a polyglutamine tract containing protein, accumulates in Alzheimer's disease. in Brain research. Molecular brain research 2004 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen TBP Interaktionspartner

Fruit Fly (Drosophila melanogaster) TATA Box Binding Protein (TBP) Interaktionspartner

  1. Results indicate that a portion of Brf1 is sandwiched between Bdp1 and TBP upstream of the U6 TATA box. Furthermore, Bdp1 traverses the DNA under the N-terminal stirrup of TBP to interact with the DNA (and very likely Brf1) downstream of the TATA sequence.

  2. TFIID (zeige TAF8 Antikörper) has two disctinct modes of transcription initiation, de novo initiation and reinitiation, as revealed by the inhibitory effect of TFIID (zeige TAF8 Antikörper)-bound tin (zeige MSH2 Antikörper) compounds on the de novo initiation, but not on the reinitiation.

  3. Deactivation of TBP contributes to SCA17 pathogenesis.

  4. Aptamers generated by both selections were able to bind specifically to TBP, but the two groups showed characteristics which were clearly different in terms of their capability to compete with TATA-DNA.

  5. in fruit flies, different classes of RNA polymerase III promoters differentially utilize TBP and TRF1 (zeige TERF1 Antikörper) for the initiation of transcription.

  6. Tbp targets core histone transcription.

  7. TBP activates TATA-dependent transcription and represses DPE-dependent transcription, whereas Mot1 (zeige BTAF1 Antikörper) and NC2 (zeige GTF2H5 Antikörper) block TBP function and thus repress TATA-dependent transcription and activate DPE-dependent transcription.

Human TATA Box Binding Protein (TBP) Interaktionspartner

  1. Data indicate the crystal structure of a Brf2 (zeige ZFP36L2 Antikörper)-TBP-Bdp1 (zeige PTPN18 Antikörper) complex bound to a DNA promoter.

  2. Study could not determine a definitive cutoff value for the pathologic CAG repeat (zeige CELF3 Antikörper) number of SCA17.

  3. TBP attenuates Msx1 (zeige MSX1 Antikörper)-mediated glycoprotein hormone alpha (zeige CGA Antikörper) transcriptional repression.

  4. this analysis of the 2.2-kb doubly spliced RNA (2.2DS-RNA) -mediated suppression of viral RNA expression showed that 2.2DS-RNA inhibited transcription via binding to the TATA-binding protein and stress granule proteins.

  5. Our results provide first evidence that Taspase1 processing affects TFIIA (zeige GTF2A1 Antikörper) regulation of TFIID and suggest that Taspase1 processing of TFIIA (zeige GTF2A1 Antikörper) is required to establish INR (zeige INSR Antikörper)-selective core promoter activity in the presence of NC2 (zeige GTF2H5 Antikörper).

  6. TBP (and GATA2 (zeige GATA2 Antikörper) and Sp1 (zeige PSG1 Antikörper)) have key roles in inflammation and ischemia-like conditions through MAOA (zeige MAOA Antikörper) regulation.

  7. Deactivation of TBP contributes to SCA17 pathogenesis.

  8. HOXA2 (zeige HOXA2 Antikörper) acts as a suppressor or TBP-antagonist to inhibit MMP-9 (zeige MMP9 Antikörper) expression; while methylation-mediated inactivation of HOXA2 (zeige HOXA2 Antikörper) in NPC (zeige NPC1 Antikörper) derepresses MMP-9 (zeige MMP9 Antikörper) production and increases invasion of NPC (zeige NPC1 Antikörper) cells.

  9. The data reveal synergistic effects of H3K4me3, H3K14ac and a TATA box sequence on TFIID binding in vitro. Stoichiometry analyses of affinity purified human TFIID identified the presence of a stable dimeric core.

  10. The UL4 protein directly interacted with the host TBP and the carboxy-terminal domain of RNA polymerase II in infected cells.

Zebrafish TATA Box Binding Protein (TBP) Interaktionspartner

  1. TBP plays an important role in the degradation of a specific subset of maternal mRNAs during late blastulation/early gastrulation, which involves targets of the miR (zeige MYLIP Antikörper)-430 pathway.

Mouse (Murine) TATA Box Binding Protein (TBP) Interaktionspartner

  1. the TAF10-containing canonical TFIID and SAGA complexes are dispensable for early paraxial mesoderm development, arguing against the generic role in transcription proposed for these fully assembled holo-complexes

  2. Our study establishes glial dysfunction as an important component of SCA17 pathogenesis and suggests targeting glial inflammation as a potential therapeutic approach for SCA17 treatment.

  3. This evidence demonstrates that TBP2 (zeige Tbpl2 Antikörper) does not replace TBP during muscle differentiation, as previously proposed, with limiting amounts of TFIID-TBP being required to promote muscle-specific (zeige EIF3K Antikörper) gene expression

  4. The large TBP polyQ repeat decreases the association of MyoD with TBP and DNA promoters and causes muscle degeneration in spinocerebellar ataxia 17 transgenic mice.

  5. Thus, modulating the levels of both Huwe1 and USP10 (zeige USP10 Antikörper) appears to fine-tune the requisite degradation of TBP during myogenesis.

  6. This study demonistrated that denervation-induced muscle atrophy on Tbp expression in mice.

  7. The results of this study confirmed motor deficits in the Tbp/Q71 mice and present previously unrecognized behavioral characteristics obtained from the automated home cage, indicating its use for high-throughput screening and testing.

  8. TBP might be a marker for transmitting cellular memory to daughter cells.

  9. we show that the differentiation of fetal liver progenitors to adult hepatocytes involves a wholesale depletion of canonical cofactor required for Sp1 activation/Mediator and TFIID complexes at both the RNA and protein level

  10. Alcohol induces RNA polymerase III-dependent transcription through c-Jun (zeige JUN Antikörper) by co-regulating TATA-binding protein (TBP) and Brf1 (zeige ZFP36L1 Antikörper) expression.

TBP Antigen-Profil

Protein Überblick

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminus. This region of the protein modulates the DNA binding activity of the C terminus, and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription. The number of CAG repeats encoding the polyglutamine tract is usually 32-39, and expansion of the number of repeats increases the length of the polyglutamine string and is associated with spinocerebellar ataxia 17, a neurodegenerative disorder classified as a polyglutamine disease. Two transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit TBP

  • TATA binding protein (Tbp) Antikörper
  • TATA box binding protein (TBP) Antikörper
  • TATA box binding protein (tbp) Antikörper
  • TATA box binding protein (tbp-a) Antikörper
  • TATA box binding protein (Tbp) Antikörper
  • TATA-box-binding protein (Tbp) Antikörper
  • CG9874 Antikörper
  • Dmel\\CG9874 Antikörper
  • dtbp Antikörper
  • dTFIID Antikörper
  • fd20h06 Antikörper
  • Gtf2d Antikörper
  • gtf2d1 Antikörper
  • HDL4 Antikörper
  • RBP Antikörper
  • sca17 Antikörper
  • si:zc101n13.2 Antikörper
  • tbp Antikörper
  • TBP1 Antikörper
  • TBP38 Antikörper
  • tfiid Antikörper
  • tfiidtau Antikörper
  • wu:fd20h06 Antikörper
  • xtbp Antikörper
  • zgc:66213 Antikörper

Bezeichner auf Proteinebene für TBP

42kDa polypeptide , CG9874-PA , TATA box binding protein , TATA box-binding protein , TATA-binding protein , TATA-box binding protein , Tbp-PA , TATA binding protein , TATA-box-binding protein , TATA sequence-binding protein , TATA-box binding protein N-terminal domain , TATA-box factor , transcription initiation factor TFIID TBP subunit , TATA-binding factor , zTBP , zfTBF , transcription factor , TA-TA binding protein 1 , TFIID core protein , Transcription initiation factor TFIID TBP subunit

GENE ID SPEZIES
37476 Drosophila melanogaster
431689 Canis lupus familiaris
696258 Macaca mulatta
738472 Pan troglodytes
100101451 Takifugu rubripes
100380389 Salmo salar
6908 Homo sapiens
368882 Danio rerio
399465 Xenopus laevis
395995 Gallus gallus
611193 Canis lupus familiaris
516578 Bos taurus
21374 Mus musculus
117526 Rattus norvegicus
100144760 Ovis aries
780434 Sus scrofa
101839769 Mesocricetus auratus
692612 Bombyx mori
Ausgewählte Anbieter für anti-TBP (TBP) Antikörper
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