anti-Synuclein, alpha Interacting Protein (SNCAIP) Antikörper

SNCAIP encodes a protein containing several protein-protein interaction domains, including ankyrin-like repeats, a coiled-coil domain, and an ATP/GTP-binding motif. Zusätzlich bieten wir Ihnen SNCAIP Proteine (6) und SNCAIP Kits (2) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
SNCAIP 9627 Q9Y6H5
SNCAIP 307309  
SNCAIP 67847  
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Top anti-SNCAIP Antikörper auf antikoerper-online.de

Showing 10 out of 60 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert EIA, WB The anti-Synphilin-1 C-term Pab is used in Western blot to detect Synphilin-1 in mouse brain lysate. 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Anti-Synphilin-1 Polyclonal Antibody, Unconjugated (ABIN736163) at 1:200 followed by conjugation to the secondary antibody and DAB staining. Rat brain lysates probed with Anti Synphilin-1 Polyclonal Antibody, Unconjugated (ABIN736163) at 1:200 in 4 °C. Followed by conjugation to secondary antibody at 1:3000 90min in 37 °C. Predicted band 100kD. Observed band size:60kD 100kD. 100 μL Anmelden zum Anzeigen 9 bis 12 Tage
304,36 €
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Human Kaninchen Unkonjugiert WB The anti-Synphilin-1 C-term Pab (ABIN390382) is used in Western blot to detect Synphilin-1 in mouse brain lysate. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
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Human Kaninchen Unkonjugiert ELISA, IHC, WB 100 μL Anmelden zum Anzeigen 13 Days
154,33 €
Details
Human Kaninchen Unkonjugiert IHC, WB Immunohistochemical analysis of Synphilin 1 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of Synphilin 1 expression in HeLa (A), U2OS (B) whole cell lysates. 200 μL Anmelden zum Anzeigen 11 bis 13 Tage
464,29 €
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Human Kaninchen Alexa Fluor 594 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
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Human Kaninchen HRP IHC (p), WB   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
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Human Kaninchen Cy7 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
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Human Kaninchen FITC IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
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Human Kaninchen Cy3 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
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SNCAIP Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-SNCAIP Antikörper

  1. Human Polyclonal SNCAIP Primary Antibody für IF, IHC (p) - ABIN2476664 : Büttner, Delay, Franssens, Bammens, Ruli, Zaunschirm, de Oliveira, Outeiro, Madeo, Buée, Galas, Winderickx: Synphilin-1 enhances ?-synuclein aggregation in yeast and contributes to cellular stress and cell death in a Sir2-dependent manner. in PLoS ONE 2010 (PubMed)

Weitere Antikörper gegen SNCAIP Interaktionspartner

Human Synuclein, alpha Interacting Protein (SNCAIP) Interaktionspartner

  1. Differential expression of synphilin-1 isoforms (and alpha-synuclein (zeige SNCA Antikörper) and parkin (zeige PARK2 Antikörper)) was found in multiple system atrophy brains compared to control brain.

  2. Synphilin-1 binds ATP, but not CTP (zeige CDS1 Antikörper).

  3. Overexpression of human synphilin-1 in mice resulted in hyperphagia and obesity.

  4. Overexpression of SP1 (zeige PSG1 Antikörper) in neurons, but not peripheral cells, increased the body weight of flies compared with that of non-transgenic controls. SP1 (zeige PSG1 Antikörper) increased food intake but did not affect locomotor activity

  5. Although serine-129 phosphorylation of alpha-synuclein (zeige SNCA Antikörper) facilitates tubulin polymerization promoting protein (TPPP (zeige Tppp Antikörper))-mediated alpha-SYN oligomerization, this modification does not seem to play an inevitable role in the early step of alpha-SYN oligomer formation.

  6. Mutation screening of SNCAIP identifies novel sequence variants using a bioinformatic approach; further studies are necessary to determine their possible functional consequences in South African patients with Parkinson's disease.

  7. Neuronal survival factor MEF2D (zeige MEF2D Antikörper) is decreased in human and experimental Parkinson's disease, a decrease that is specifically associated with alpha-synuclein (zeige SNCA Antikörper) accumulation and aggregation.

  8. Synphilin-1 inhibits alpha-synuclein (zeige SNCA Antikörper) degradation by the proteasome.

  9. Knockdown of Herp (zeige HERPUD1 Antikörper) gene unexpectedly facilitated the degradation of synphilin-1, and improved cell viability during proteasomal inhibition.

  10. Data show that periphilin (zeige PPHLN1 Antikörper) displays an overlapping expression pattern with synphilin-1 in cellular and animal models and in Lewy bodies of Parkinson's disease (PD) patients, and support involvement of periphilin (zeige PPHLN1 Antikörper) in PD.

Mouse (Murine) Synuclein, alpha Interacting Protein (SNCAIP) Interaktionspartner

  1. This study shows that alpha-synuclein (zeige SNCA Antikörper) is present in cerebellar glutamatergic terminals.

  2. These results suggest that increased levels of NUB1 (zeige NPM3 Antikörper) play a potential role in degradation of detergent-insoluble alpha-synuclein (zeige SNCA Antikörper) in vivo, although it is insufficient to degrade abnormal alpha-synuclein (zeige SNCA Antikörper) in Lewy body disease model mice.

  3. SP1 (zeige SP1 Antikörper) results in a CCK (zeige CCK Antikörper) response deficiency that may contribute to the increased meal size and overall hyperphagia in synphillin-1 transgenic mice

  4. TEM (zeige TNMD Antikörper) analysis of protein:inhibitor assays demonstrated that scyllo-inositol inhibits the aggregation of alpha-synuclein (zeige SNCA Antikörper), suggesting the therapeutic potential of the small molecule in PD.

  5. We exploited atomic force microscopy (AFM (zeige AFM Antikörper)) for the selective, nanoscale confinement of alpha-Synuclein (zeige SNCA Antikörper) on gold to study the early stages of alpha-Synuclein (zeige SNCA Antikörper) aggregation and the effect of small molecules, like dopamine, on the aggregation process.

  6. Sncaip physically interacts with PPP1 and affects PPP1 sorting to subcellular compartments.

  7. Studies identify a novel function of synphilin-1 in controlling food intake and body weight, and may provide a unique obesity model for future studies of obesity pathogenesis and therapeutics.

  8. Synphilin-1 can diminish the severity of alpha-synucleinopathy and play a neuroprotective role against A53T alpha-synuclein (zeige SNCA Antikörper) toxicity in vivo.

  9. synphilin-1 has a role in skill learning and motor performance

  10. expression of synphilin-1 shortens N1E-115 cell division doubling time, promotes neurite outgrowth, and protects against Rotenone-induced toxicity; synphilin-1 displays a neurotrophic effect in vitro, may play a neuroprotective role in Parkinson's disease

SNCAIP Antigen-Profil

Protein Überblick

This gene encodes a protein containing several protein-protein interaction domains, including ankyrin-like repeats, a coiled-coil domain, and an ATP/GTP-binding motif. The encoded protein interacts with alpha-synuclein in neuronal tissue and may play a role in the formation of cytoplasmic inclusions and neurodegeneration. A mutation in this gene has been associated with Parkinson's disease. Alternatively spliced transcript variants encoding different isoforms of this gene have been described, but the full-length nature of only two have been determined.

Genbezeichner und Symbole assoziert mit SNCAIP

  • synuclein, alpha interacting protein (SNCAIP) Antikörper
  • synuclein, alpha interacting protein (synphilin) (sncaip) Antikörper
  • synuclein, alpha interacting protein (sncaip) Antikörper
  • synuclein, alpha interacting protein (synphilin) (LOC100221074) Antikörper
  • synuclein, alpha interacting protein (Sncaip) Antikörper
  • synuclein, alpha interacting protein (synphilin) (Sncaip) Antikörper
  • 2810407O15Rik Antikörper
  • 4933427B05Rik Antikörper
  • BB104594 Antikörper
  • LOC100221074 Antikörper
  • MGC88953 Antikörper
  • SNCAIP Antikörper
  • Sph1 Antikörper
  • Syph1 Antikörper

Bezeichner auf Proteinebene für SNCAIP

synuclein, alpha interacting protein , synuclein, alpha interacting protein (synphilin) , synphilin-1-like , alpha-synuclein-interacting protein , synphilin-1 , synuclein alpha interacting protein , synphilin-1 variant 1e

GENE ID SPEZIES
100063985 Equus caballus
448237 Xenopus (Silurana) tropicalis
700372 Macaca mulatta
462021 Pan troglodytes
100406168 Callithrix jacchus
100481199 Ailuropoda melanoleuca
100559476 Anolis carolinensis
100221074 Taeniopygia guttata
9627 Homo sapiens
307309 Rattus norvegicus
426796 Gallus gallus
100720184 Cavia porcellus
67847 Mus musculus
481479 Canis lupus familiaris
100049698 Sus scrofa
540156 Bos taurus
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