Synaptotagmin Like Protein 2 Proteine (SYTL2)

The protein encoded by SYTL2 is a synaptotagmin-like protein (SLP) that belongs to a C2 domain-containing protein family. Zusätzlich bieten wir Ihnen SYTL2 Antikörper (22) und SYTL2 Kits (4) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
SYTL2 83671 Q99N50
Ratte SYTL2 SYTL2 361604  
SYTL2 54843 Q9HCH5
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Showing 4 out of 6 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 66 Days
10.536,00 €
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Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 66 Days
10.536,00 €
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HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 6 bis 8 Tage
748,00 €
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HOST_Escherichia coli (E. coli) Human S tag,His tag   100 μg Anmelden zum Anzeigen 13 bis 17 Tage
652,38 €
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SYTL2 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine)

Human , ,
, ,

Weitere Proteine zu Synaptotagmin Like Protein 2 (SYTL2) Interaktionspartnern

Mouse (Murine) Synaptotagmin Like Protein 2 (SYTL2) Interaktionspartner

  1. Our findings indicate that Slp2-a controls renal cell size through regulation of Rap (zeige LRPAP1 Proteine)-ezrin (zeige EZR Proteine) signaling independently of Rab27 (zeige RAB27A Proteine).

  2. Slp2-a is required for targeting of the signaling molecule podocalyxin (zeige PODXL Proteine) to the apical membrane in a Rab27A (zeige RAB27A Proteine)-dependent manner.

  3. Calmodulin (zeige Calm2 Proteine) suppresses synaptotagmin-2 (zeige SYT2 Proteine) transcription in cortical neurons

  4. Loss of Slp2-a protein also induced a change in melanocyte morphology, from their normal elongated shape to a more rounded shape, which depended on the phospholipid-binding activity of Slp2-a

  5. Slp2-a is part of the mucin (zeige SLC13A2 Proteine) secretory machinery in surface mucous cells of mouse stomach

  6. These results suggest that both Slp1 and Slp2-a may form part of a docking complex, capturing secretory lysosomes at the immunological synapse.

  7. The structural characterization of the Rab27a (zeige RAB27A Proteine)-exophilin4/Slp2-a complex will clarify Rab27 (zeige RAB27A Proteine) recognition by its effectors prior to vesicle tethering and docking.

  8. The observed structural complementation between the interacting surfaces of Rab27a (zeige RAB27A Proteine) and Exophilin4 sheds light on the disparities among the Rab27 (zeige RAB27A Proteine) effectors and outlines a general mechanism for their recruitment.[exophilin4]

  9. Syt2 (zeige SYT2 Proteine) can serve as an exocytic sensor for diverse Ca(2 (zeige CA2 Proteine)+) signaling systems, and its levels are limiting for stimulated secretory function in airway goblet cells

  10. Stress-induced mitochondrial hyperfusion (SIMH) is independent of MFN2, BAX/BAK, and prohibitins, but requires L-OPA1, MFN1, and the mitochondrial inner membrane protein SLP-2.

Human Synaptotagmin Like Protein 2 (SYTL2) Interaktionspartner

  1. Overexpression of SYTL2 promoted metastatic potential.

  2. SLP2 may play an important role in tumorigenesis of esophageal squamous cell carcinoma.

  3. A high expression level of SLP-2 may be associating with the development of invasion and metastasis in laryngeal squamous cell carcinoma and breast cancer.

  4. Calmodulin (zeige CALM1 Proteine) suppresses synaptotagmin-2 (zeige SYT2 Proteine) transcription in cortical neurons

  5. Exophilin4/Slp2-a is specifically expressed in pancreatic alpha cells.

  6. These results suggest that both Slp1 and Slp2-a may form part of a docking complex, capturing secretory lysosomes at the immunological synapse.

  7. Rab27a (zeige RAB27A Proteine) recruits Slp2a-hem on vesicular structures in peripheral CTLs and following CTL-target (zeige CTH Proteine) cell conjugate formation, the Slp2a-hem/Rab27a (zeige RAB27A Proteine) complex colocalizes with perforin (zeige PRF1 Proteine)-containing granules at the immunologic synapse

  8. Rab27A/Slp2a expression in limb girdle muscular dystrophy 2B muscle provides a compensatory vesicular trafficking pathway that is able to repair membrane damage in the absence of dysferlin.

  9. Synaptotagmin-like protein 2-a (Slp2-a) contains an N-terminal Slp (zeige SEPT9 Proteine) homology domain (SHD (zeige SHD Proteine)) (PMID: 11327731). The SHD (zeige SHD Proteine) of Slp2-a specifically and directly binds the GTP (zeige AK3 Proteine)-bound form of Rab27A (zeige RAB27A Proteine).

SYTL2 Protein Überblick

Protein Überblick

The protein encoded by this gene is a synaptotagmin-like protein (SLP) that belongs to a C2 domain-containing protein family. The SLP homology domain (SHD) of this protein has been shown to specifically bind the GTP-bound form of Ras-related protein Rab-27A (RAB27A). This protein plays a role in RAB27A-dependent vesicle trafficking and controls melanosome distribution in the cell periphery. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Genbezeichner und Symbole assoziert mit SYTL2

  • synaptotagmin-like 2 (Sytl2)
  • synaptotagmin-like 2 (SYTL2)
  • AI266830 Protein
  • CHR11SYT Protein
  • EXO4 Protein
  • mKIAA1597 Protein
  • SGA72M Protein
  • SLP2 Protein
  • Slp2-a Protein
  • Slp2-b Protein
  • Slp2-c Protein
  • Slp2-d Protein
  • SLP2A Protein

Bezeichner auf Proteinebene für SYTL2

exophilin-4 , synaptotagmin-like protein 2 , breast cancer-associated antigen SGA-72M , chromosome 11 synaptotagmin

GENE ID SPEZIES
83671 Mus musculus
361604 Rattus norvegicus
54843 Homo sapiens
614406 Bos taurus
Ausgewählte Anbieter für SYTL2 Proteine (SYTL2)
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