Synapsin II Proteine (SYN2)

SYN2 is a member of the synapsin gene family. Zusätzlich bieten wir Ihnen Synapsin II Antikörper (34) und Synapsin II Kits (1) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
SYN2 6854  
SYN2 20965 Q64332
Ratte SYN2 SYN2 29179 Q63537
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Showing 4 out of 4 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 56 Days
7.380,00 €
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Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 56 Days
7.380,00 €
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HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
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HOST_Escherichia coli (E. coli) Maus T7 tag,His tag   100 μg Anmelden zum Anzeigen 13 bis 17 Tage
573,33 €
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SYN2 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
,
Mouse (Murine) ,
,

Weitere Proteine zu Synapsin II (SYN2) Interaktionspartnern

Human Synapsin II (SYN2) Interaktionspartner

  1. These findings contribute to previous work showing dysregulation of Synapsins, particularly SYN2, in mood disorders and improve our understanding of the regulatory mechanisms that precipitate these changes likely leading to the BD or MDD phenotype.

  2. Both GABRA6 (zeige GABRA6 Proteine) and Synapsin II polymorphisms are important risk factors for the development of idiopathic generalized epilepsy in a South Indian population.

  3. Results identify SYN2 as a novel predisposing gene for autism spectrum disorders (ASD (zeige ARSD Proteine)) and strengthen the hypothesis that a disturbance of synaptic homeostasis underlies ASD (zeige ARSD Proteine).

  4. Synapsin II is involved in the molecular pathway of lithium treatment in bipolar disorder

  5. SYN2 rs3773364 A>G polymorphism is not a risk factor for susceptibility to epilepsy in this case-control study and meta-analysis.

  6. Results from our study indicate the involvement of SYN2 gene polymorphism in conferring risk to epilepsy; however, the genetic variant does not seem to modulate drug-response in epilepsy pharmacotherapy.

  7. This study suggests a positive association between synapsin II and schizophrenia, implying that synapsin II is involved in the etiology of schizophrenia.

  8. synapsin II variants are associated with susceptibility to schizophrenia.

  9. Syn2 is likely to be involved in the etiology or pathogenesis of schizophrenia.

  10. A case-control study with synapsin II was conducted in 506 bipolar disorder patients and 507 healthy individuals from the Han Chinese population. No association was found in this study.

Mouse (Murine) Synapsin II (SYN2) Interaktionspartner

  1. These results reveal a new SynII function in the regulation of the time course of GABA release and demonstrate that this function is dependent on the interneuron subtype.

  2. This study demonstrated that synapsin 2 regulating GABA Release from Hippocampal Interneurons.

  3. Pharmacological and knockdown experiments showed that activation of sympathetic neurons by SCFA propionate involves SCFA receptor GPR41 (zeige FFAR3 Proteine) linking to Gbetagamma-PLCbeta3-ERK1/2-synapsin 2

  4. Deletion of synapsin II, a presynaptic protein contributing to epilepsy predisposition in humans, leads to a loss of tonic inhibition in mouse hippocampal slices due to a dramatic decrease in presynaptic asynchronous GABA release.

  5. In synapsin II(-) hippocampal neurons an overexcitable phenotype was observed.

  6. This study demonstrated a seizure-inducing potential of regular handling in both Syn1KO and Syn2KO mice during a period between P21 and 4 1/2 months of age.

  7. Behavioral and neurophysiological features of Syn-2 (zeige STX2 Proteine) knockout mice are characterized by observation of the development and progress of seizures from postnatal day 20 to 180.

  8. The histone modification marks were significantly increased in bipolar disorder and major depression and this effect was correlated with significant increases in syn2 gene expression.

  9. Syn (zeige SYP Proteine) II promotes gamma-aminobutyric acid asynchronous release in a Ca(2 (zeige CA2 Proteine)+)-dependent manner.

  10. Analysis of cultured neurons from wild-type and Syn (zeige SYP Proteine) I,II,III-deficient triple knock-out (TKO (zeige MRPS12 Proteine)) mice shows that synaptic vesicles are severely dispersed in the absence of Syns.

Synapsin II (SYN2) Protein Überblick

Protein Überblick

This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family encodes a neuron-specific phosphoprotein that selectively binds to small synaptic vesicles in the presynaptic nerve terminal. The TIMP4 gene is located within an intron of this gene and is transcribed in the opposite direction. Mutations in this gene may be associated with abnormal presynaptic function and schizophrenia. Alternative splicing of this gene results in two transcripts.

Genbezeichner und Symbole assoziert mit Synapsin II Proteine (SYN2)

  • synapsin II (syn2-a)
  • synapsin II (SYN2)
  • synapsin IIa (syn2a)
  • synapsin II (syn2)
  • synapsin-2 (EDI_190690)
  • synapsin II (Syn2)
  • 2900074L19Rik Protein
  • AI836018 Protein
  • AI841723 Protein
  • MGC115109 Protein
  • syn1 Protein
  • SYN2 Protein
  • SYNII Protein
  • SYNIIa Protein
  • SYNIIb Protein
  • zgc:92311 Protein

Bezeichner auf Proteinebene für Synapsin II Proteine (SYN2)

synapsin II , synapsin IIa , synapsin-2 , synapsin2 , synapsin-2-like , synapsin 2

GENE ID SPEZIES
373810 Xenopus laevis
415963 Gallus gallus
436870 Danio rerio
734421 Xenopus laevis
749839 Pan troglodytes
751980 Taeniopygia guttata
100057285 Equus caballus
100484945 Ailuropoda melanoleuca
100541419 Meleagris gallopavo
5878744 Entamoeba dispar SAW760
6854 Homo sapiens
20965 Mus musculus
29179 Rattus norvegicus
484652 Canis lupus familiaris
782758 Bos taurus
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