anti-Symplekin (SYMPK) Antikörper

SYMPK encodes a nuclear protein that functions in the regulation of polyadenylation and promotes gene expression. Zusätzlich bieten wir Ihnen Symplekin Proteine (6) und Symplekin Kits (2) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
SYMPK 8189 Q92797
SYMPK 292683  
SYMPK 68188  
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Top anti-Symplekin Antikörper auf antikoerper-online.de

Showing 10 out of 53 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert WB <b>WB Suggested Anti-SYMPK Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>HepG2 cell lysate WB Suggested Anti-SYMPK <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500 <br /> Positive Control: HepG2 cell lysate <br /> SYMPK is supported by BioGPS gene expression data to be expressed in HepG2 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Huhn Maus Unkonjugiert IF, IP, IHC, WB Western blot analysis of Symplekin on a PC12 cell lysate (Rat neuroblastoma, ATCC CRL-1721). Lane 1: 1:1000, lane 2: 1:2000, lane 3: 1:4000 dilution of the mouse anti-Symplekin antibody. Immunofluorescence staining of PC12 cells (Rat neuroblastoma, ATCC CRL-1721). 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
$168.74
Details
Human Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert IP, WB Western Blot: Symplekin Antibody  - Detection of Human and Mouse Symplekin by Western Blot. Samples: Whole cell lysate from HeLa, (5, 15 and 50 ug), and 293T (50ug) cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-Symplekin antibody  used for WB at 0.02 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes. 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$556.31
Details
Human Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert IF, IHC, WB Western blot analysis of extract of various cells, using SPK antibody. 100 μL Anmelden zum Anzeigen 16 Days
$476.15
Details
Human Maus Unkonjugiert IHC (fro), WB   5 mL Anmelden zum Anzeigen 6 bis 8 Tage
$357.50
Details
Human Kaninchen Unkonjugiert ELISA, WB 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$446.88
Details
Human Maus Unkonjugiert IF, WB Immunofluorescence of monoclonal antibody to SYMPK on HeLa cell (antibody concentration 10 µg/mL). SYMPK monoclonal antibody (M03), clone 4C2 Western Blot analysis of SYMPK expression in COLO 320 HSR. 0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$450.00
Details

SYMPK Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Symplekin Antikörper

  1. Chicken Monoclonal SYMPK Primary Antibody für IF, IP - ABIN968084 : Cordenonsi, DAtri, Hammar, Parry, Kendrick-Jones, Shore, Citi: Cingulin contains globular and coiled-coil domains and interacts with ZO-1, ZO-2, ZO-3, and myosin. in The Journal of cell biology 2000 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen Symplekin Interaktionspartner

Fruit Fly (Drosophila melanogaster) Symplekin (SYMPK) Interaktionspartner

  1. Authors propose a model in which the core cleavage complex formation is mediated by CPSF73 (zeige CPSF3 Antikörper), CPSF100 (zeige CPSF2 Antikörper), and Symplekin C-termini, and the N-terminal region of Symplekin facilitates cotranscriptional 3' end processing of histone mRNAs.

  2. This localization depends on the RNA binding protein ypsilon schachtel. CPSF-73 (zeige CPSF3 Antikörper) and a number of mRNAs are localized at this same site, suggesting that Symplekin participates in cytoplasmic polyadenylation at tricellular junctions.

  3. Together, these data support the conclusion that the Symplekin HEAT domain serves as a scaffold for protein-protein interactions essential to the mRNA maturation process.

Arabidopsis thaliana Symplekin (SYMPK) Interaktionspartner

Human Symplekin (SYMPK) Interaktionspartner

  1. Data indicate rs56848936 in the gene symplekin protein (SYMPK) at 19q13.3, associated with colon cancer risk.

  2. CPSF2 (zeige CPSF2 Antikörper) and SYMPK, are RBFOX2 (zeige RBM9 Antikörper) cofactors for both inclusion and exclusion of internal exons.

  3. Symplekin interacts and co-localizes with both MOZ (zeige MYST3 Antikörper) and MLL (zeige MLL Antikörper) in immature hematopoietic cells. Its inhibition leads to a decrease of the HOXA9 (zeige HOXA9 Antikörper) protein level but not of Hoxa9 (zeige HOXA9 Antikörper) mRNA.

  4. Symplekin expression regulates the assembly of tight junctions, thus helps to maintain the integrity of the epithelial monolayer and cellular polarity.

  5. crystal structure at 2.4 A resolution of the amino-terminal domain (residues 30-340) of human symplekin in a ternary complex with the Pol II carboxy-terminal domain (CTD) Ser (zeige SIGLEC1 Antikörper) 5 phosphatase Ssu72 (zeige SSU72 Antikörper) and a CTD Ser (zeige SIGLEC1 Antikörper) 5 phosphopeptide

  6. Symplekin supports faithful mitosis by contributing to the formation of a bipolar spindle apparatus. Depletion of symplekin attenuates microtubule polymerization as well as expression of the critical microtubule polymerization protein CKAP5 (TOGp (zeige CKAP5 Antikörper)).

  7. Data show that claudin-2 (zeige CLDN2 Antikörper) expression was reduced following symplekin down-regulation, and siRNA-mediated claudin-2 (zeige CLDN2 Antikörper) down-regulation increased the transepithelial resistance and decreased cyclin D1 (zeige CCND1 Antikörper) expression and ZONAB (zeige CSDA Antikörper) nuclear localization.

  8. symplekin has a role in HSF1 (zeige HSF1 Antikörper) modulation of Hsp70 (zeige HSP70 Antikörper) mRNA polyadenylation

  9. The decreased expression of symplekin may be an early step in the transformation of hepatocytes, whereas alteration of the expression of adherens junctions and desmosomes may indicate more serious changes.

  10. The symplekin/ZONAB (zeige CSDA Antikörper) complex inhibits intestinal cell differentiation by the repression of AML1/Runx1 (zeige RUNX1 Antikörper).

Xenopus laevis Symplekin (SYMPK) Interaktionspartner

  1. Here, we identify a new factor essential for polyadenylation, namely, symplekin, a CPEB and CPSF (zeige CPSF2 Antikörper) binding protein that serves as a scaffold upon which regulatory factors are assembled

Symplekin (SYMPK) Antigen-Profil

Protein Überblick

This gene encodes a nuclear protein that functions in the regulation of polyadenylation and promotes gene expression. The protein forms a high-molecular weight complex with components of the polyadenylation machinery. It is thought to serve as a scaffold for recruiting regulatory factors to the polyadenylation complex. It also participates in 3'-end maturation of histone mRNAs, which do not undergo polyadenylation. The protein also localizes to the cytoplasmic plaques of tight junctions in some cell types.

Genbezeichner und Symbole assoziert mit anti-Symplekin (SYMPK) Antikörper

  • Symplekin (Sym) Antikörper
  • symplekin (sympk) Antikörper
  • symplekin (SYMPK) Antikörper
  • symplekin (LOC552752) Antikörper
  • HEAT repeat-containing protein (ESP4) Antikörper
  • symplekin (AT1G27595) Antikörper
  • symplekin (LOC5580150) Antikörper
  • symplekin (CpipJ_CPIJ011126) Antikörper
  • Symplekin (Bm1_50390) Antikörper
  • symplekin (NAEGRDRAFT_80124) Antikörper
  • symplekin (LOAG_00841) Antikörper
  • symplekin (Sympk) Antikörper
  • symplekin S homeolog (sympk.S) Antikörper
  • 1500016F02Rik Antikörper
  • 4632415H16Rik Antikörper
  • AA125406 Antikörper
  • AI449890 Antikörper
  • CG2097 Antikörper
  • DKFZp468C0711 Antikörper
  • Dmel\\CG2097 Antikörper
  • dSymp Antikörper
  • ENHANCED SILENCING PHENOTYPE 4 Antikörper
  • Hfn3g Antikörper
  • MGC75595 Antikörper
  • SPK Antikörper
  • SYM Antikörper
  • SYMPK Antikörper
  • T10O8.110 Antikörper
  • T10O8_110 Antikörper
  • T22C5.3 Antikörper

Bezeichner auf Proteinebene für anti-Symplekin (SYMPK) Antikörper

CG2097-PA , Sym-PA , symplekin , Symplekin , symplekin-like , hepatocyte nuclear factor 3 gamma

GENE ID SPEZIES
40709 Drosophila melanogaster
394872 Xenopus (Silurana) tropicalis
456142 Pan troglodytes
476431 Canis lupus familiaris
552752 Apis mellifera
831597 Arabidopsis thaliana
839651 Arabidopsis thaliana
5580150 Aedes aegypti
6043768 Culex quinquefasciatus
6104963 Brugia malayi
8853240 Naegleria gruberi strain NEG-M
9938210 Loa loa
100010885 Monodelphis domestica
100070949 Equus caballus
100174376 Pongo abelii
100179022 Ciona intestinalis
100348044 Oryctolagus cuniculus
100412467 Callithrix jacchus
100474335 Ailuropoda melanoleuca
100512609 Sus scrofa
8189 Homo sapiens
292683 Rattus norvegicus
100337373 Bos taurus
68188 Mus musculus
379378 Xenopus laevis
Ausgewählte Anbieter für anti-Symplekin (SYMPK) Antikörper
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