Surfactant Protein C (SFTPC) ELISA Kits

SFTPC encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Zusätzlich bieten wir Ihnen Surfactant Protein C Antikörper (120) und Surfactant Protein C Proteine (9) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
SFTPC 20389  
SFTPC 6440 P11686
SFTPC 50683 P11685
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Top Surfactant Protein C ELISA Kits auf antikoerper-online.de

Showing 10 out of 47 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 2.34 pg/mL 9.37-600 pg/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 11 bis 15 Tage
772,39 €
Details
Maus 0.58 ng/mL 2.3-150 ng/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 11 bis 15 Tage
772,39 €
Details
Ratte 1.17 pg/mL 4.69-300 pg/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 11 bis 15 Tage
874,71 €
Details
Human 0.112 ng/mL 0.312-20 ng/mL 96 Tests Anmelden zum Anzeigen 13 bis 16 Tage
839,64 €
Details
Ratte 0.147 ng/mL 0.312-20 ng/mL 96 Tests Anmelden zum Anzeigen 13 bis 16 Tage
898,18 €
Details
Schwein 1.56 ng/mL 6.25-400 ng/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 11 bis 15 Tage
874,71 €
Details
Rind (Kuh) 3.12 ng/mL 12.5-800 ng/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 11 bis 15 Tage
923,19 €
Details
Meerschweinchen 0.1 ng/mL 2.5-50 ng/mL   96 Tests Anmelden zum Anzeigen 13 bis 17 Tage
673,47 €
Details
Ratte 0.375 ng/mL 0.625-40 ng/mL Diagramm of the ELISA kit to detect Rat SPCwith the optical density on the x-axis and the concentration on the y-axis. 96 Tests Anmelden zum Anzeigen 10 bis 13 Tage
600,00 €
Details
Kaninchen 0.1 ng/mL 2.5-50 ng/mL   96 Tests Anmelden zum Anzeigen 13 bis 17 Tage
673,47 €
Details

Am meisten referenzierte Surfactant Protein C ELISA Kits

  1. Human Surfactant Protein C ELISA Kit für Sandwich ELISA - ABIN365768 : Uhl, Vierkotten, Wagner, Burgstaller, Costa, Koch, Lindner, Meiners, Eickelberg, Königshoff: Preclinical validation and imaging of Wnt-induced repair in human 3D lung tissue cultures. in The European respiratory journal 2015 (PubMed)
    Show all 2 Pubmed References

  2. Mouse (Murine) Surfactant Protein C ELISA Kit für Sandwich ELISA - ABIN424973 : Zhang, Zhao, Yuan, Wu, Jiang, Zhao, Luo, Xue: Autophagy regulates hyperoxia-induced intracellular accumulation of surfactant protein C in alveolar type II cells. in Molecular and cellular biochemistry 2015 (PubMed)

Weitere ELISA Kits für Surfactant Protein C Interaktionspartner

Xenopus laevis Surfactant Protein C (SFTPC) Interaktionspartner

Mouse (Murine) Surfactant Protein C (SFTPC) Interaktionspartner

  1. an intricate link between caveolin-1 (zeige CAV1 ELISA Kits) and Src kinase (zeige CSK ELISA Kits)-mediated cell signaling and alveolar epithelial cell apoptosis due to loss of SP-C expression through p53 (zeige TP53 ELISA Kits) and uPA (zeige PLAU ELISA Kits) system-mediated cross-talk, is reported.

  2. Data suggests that different SP-C mutations have unique consequences for interstitial lung diseases. Mutations here resulted in aberrant proSP-c products

  3. In vivo deficiency of SP-C leads to inflammation, increased cytokine production by type II cells, and persistent inflammation after repetitive LPS (zeige TLR4 ELISA Kits) stimulation.

  4. Transgenic restoration of SP-C reduces inflammation and improves viral clearance in the lungs of SP-C deficient mice.

  5. The SPC H2B-GFP allele allowed the FACS-based enrichment and gene expression profiling of AT2 cells.

  6. misfolded surfactant protein C has a role in endoplasmic reticulum stress in epithelial-mesenchymal transition of alveolar epithelial cells

  7. Cytoprotective-selective activated protein C (zeige PROC ELISA Kits) attenuates Pseudomonas aeruginosa-induced lung injury in mice

  8. The differential expression of mRNA by both airway level and lung region was determined for surfactant protein C.

  9. To target type II alveolar epithelial cells with this model, we generated transgenic mice that express DTR (zeige HBEGF ELISA Kits) off of the type II cell-specific surfactant protein C (SPC) promoter.

  10. Nedd4-2-mediated ubiquitination regulates lumenal relocation of SP-C, leading to processing and, ultimately, secretion of SP-C.

Human Surfactant Protein C (SFTPC) Interaktionspartner

  1. c.435G>C variant in the SFTPC gene associated with fatal neonatal respiratory distress syndrome. The c.435G>C mutation is deleterious not because of its amino acid substitution but because of its subsequent splicing defect and should be referred to as r.325_435del and p.Leu109_Gln145del.

  2. an intricate link between caveolin-1 (zeige CAV1 ELISA Kits) and Src kinase (zeige CSK ELISA Kits)-mediated cell signaling and alveolar epithelial cell apoptosis due to loss of SP-C expression through p53 (zeige TP53 ELISA Kits) and uPA (zeige PRAP1 ELISA Kits) system-mediated cross-talk, is reported.

  3. Rare mutations in surfactant-associated genes contribute to neonatal respiratory distress syndrome. The frequency of mutations in these genes in the Chinese population is unknown. We resequenced all exons of the surfactant protein-C (SFTPC) and we did not find any rare mutations in SFTPC

  4. In interstitial lung disease, abnormal proSP-C was seen in small and dense lamellar bodies in type II alveolar epithelial cells. A549 cells expressing proSP-C(L55F) had abnormal organelles. It partly colocalized in CD63 (zeige CD63 ELISA Kits)-positive cytoplasmic vesicles .

  5. We sequenced SFTPC and analyzed morphology, ultrastructure and SP expression in lung tissue when available. We identified eight subjects who were heterozygous for SP-C mutations.

  6. analysis of clinical patterns in patients with SFTPC mutations

  7. support a chaperone function of the BRICHOS domain, possibly together with the linker region, during pro-SP-C biosynthesis in the endoplasmic reticulum

  8. cleavage of BRICHOS in a loop region that is cleaved during proSP-C biosynthesis results in increased capacity to delay Abeta (zeige APP ELISA Kits)(42) fibril formation.

  9. Structural modeling of transmembrane (BRICHOS) domains of SFTPC precursor and BRI2/ITM2B (integral membrane protein 2B (zeige ITM2B ELISA Kits)) identifies conserved region structurally complementary to beta-sheet-/amyloid-prone regions in BRICHOS domain-containing proteins.

  10. (surfactant protein C), a specific functional marker of human type II alveolar epithelial cells, was detected in differentiated cells by RT-PCR (reverse transcription-PCR) analysis after day 15.

Cow (Bovine) Surfactant Protein C (SFTPC) Interaktionspartner

  1. The hydrophobic surfactant proteins SP-B and SP-C induce formation of bicontinuous inverse cubic phases.

Pig (Porcine) Surfactant Protein C (SFTPC) Interaktionspartner

  1. a potential role for SP-C in generating small surfactant structures that may participate in cholesterol mobilization and pulmonary surfactant homeostasis at the alveolar interfaces

  2. Data indicate that surfactant protein C (SP-C) structure does not seem altered by palmitoylation or the lipid environment.

  3. Data suggest that transient exposure of surfactant to polymers like hyaluronan (HA) could be a promising strategy for the production of more efficient therapeutic surfactants SP-A (zeige SFTPA1 ELISA Kits), SP-B and SP-C preparations.

  4. SP-B and SP-C proteins promote the formation of proteolipid channels in which lipid molecules are functionally involved.

  5. Palmitoylation is key for the functional cooperation of SP-C with SP-B that enables cholesterol-containing surfactant films to reach very low tensions under compression.

  6. Surfactant protein SP-B promoted film formation and reextension to lower surface tensions than SP-C.

  7. finds evidence of an interaction between cholesterol-enriched phases and SP-C, and confirms that physiological concentrations of cholesterol do not have any detrimental effect on lung surfactant with a proper lipid and protein composition

  8. study the effects of the interaction of SP-C with Dipalmitoleoylphosphatidylethanolamine on the adsorption and interfacial disintegration of phospholipid lamellar and non-lamellar phases and on the phase coexistence in insoluble DPoPE monomolecular films

Surfactant Protein C (SFTPC) Antigen-Profil

Beschreibung des Gens

This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.

Genbezeichner und Symbole assoziert mit Surfactant Protein C (SFTPC) ELISA Kits

  • surfactant protein C (SFTPC) Antikörper
  • surfactant protein C (LOC779071) Antikörper
  • surfactant, pulmonary-associated protein C (sftpc) Antikörper
  • surfactant associated protein C (Sftpc) Antikörper
  • surfactant protein C (Sftpc) Antikörper
  • BRICD6 Antikörper
  • pro-SpC Antikörper
  • PSP-C Antikörper
  • Sftp-2 Antikörper
  • SFTP2 Antikörper
  • SFTPC Antikörper
  • SMDP2 Antikörper
  • SP-C Antikörper
  • SP5 Antikörper
  • SPC Antikörper
  • xSP-C Antikörper

Bezeichner auf Proteinebene für Surfactant Protein C (SFTPC) ELISA Kits

surfactant protein C , surfactant, pulmonary-associated protein C , pulmonary surfactant-associated protein C , pulmonary surfactant-associated proteolipid SPL(Val) , BRICHOS domain containing 6 , SP5 , pulmonary surfactant apoprotein-2 SP-C , SP-C , Surfactant pulmonary-associated protein C , Surfactant, pulmonary-associated protein C , surfactant associated protein C , type I SP-C , type II SP-C

GENE ID SPEZIES
464041 Pan troglodytes
779071 Xenopus laevis
100038236 Xenopus (Silurana) tropicalis
20389 Mus musculus
6440 Homo sapiens
282071 Bos taurus
50683 Rattus norvegicus
443034 Ovis aries
100009162 Oryctolagus cuniculus
733580 Sus scrofa
477385 Canis lupus familiaris
707696 Macaca mulatta
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