Suppressor of Ty 4 Homolog 1 (S. Cerevisiae) Proteine (SUPT4H1)

SUPT4H1 encodes the small subunit of DRB (5,6-dichloro-1-beta-d-ribofuranosylbenzimidazole) sensitivity-inducing factor (DSIF) complex, which regulates mRNA processing and transcription elongation by RNA polymerase II. Zusätzlich bieten wir Ihnen Suppressor of Ty 4 Homolog 1 (S. Cerevisiae) Antikörper (19) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
SUPT4H1 6827 P63272
Ratte SUPT4H1 SUPT4H1 287608  
Maus SUPT4H1 SUPT4H1 20922 P63271
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
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Hefe Schizosaccharomyces pombe His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.086,50 €
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HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
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HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 6 bis 8 Tage
748,00 €
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Hefe Yeast His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.077,78 €
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Hefe Candida albicans His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.107,46 €
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Hefe Pongo abelii His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.119,69 €
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Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.119,69 €
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Hefe Macaca fascicularis His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.119,69 €
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Hefe Xenopus laevis His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.121,43 €
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SUPT4H1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,

Weitere Proteine zu Suppressor of Ty 4 Homolog 1 (S. Cerevisiae) (SUPT4H1) Interaktionspartnern

Fruit Fly (Drosophila melanogaster) Suppressor of Ty 4 Homolog 1 (S. Cerevisiae) (SUPT4H1) Interaktionspartner

  1. analysis of the interactions between DSIF (DRB sensitivity inducing factor), NELF (negative elongation factor (zeige RDBP Proteine)), and the Drosophila RNA polymerase II transcription elongation complex

Human Suppressor of Ty 4 Homolog 1 (S. Cerevisiae) (SUPT4H1) Interaktionspartner

  1. Chimeric transcript resulting from the fusion of RNF43 (zeige RNF43 Proteine) and SUPT4H1 was found to occur frequently in primary colorectal carcinoma.

  2. Knockdown of SUPT4H1, the human Spt4 ortholog, similarly decreased production of sense and antisense RNA foci, as well as dipeptide repeat proteins, in patient cells.

  3. crystal structure of hSpt4 in complex with the dimerization region of hSpt5 (zeige SUPT5H Proteine)

  4. Upon induction of NF-kappaB (zeige NFKB1 Proteine), a subset of target genes is regulated differentially by either P-TEFb (zeige CCNT1 Proteine) or DSIF (zeige SUPT5H Proteine).[P-TEFb (zeige CCNT1 Proteine), DSIF (zeige SUPT5H Proteine)]

  5. These findings reveal a dynamic regulation of DSIF (zeige SUPT5H Proteine) involving either E-box or NF-kappaB (zeige NFKB1 Proteine) depending on the physiological circumstances.

  6. Spt4 was purified and characterized.

  7. These results suggest that one of the functions of Spt5 is to suppress senescence and apoptosis, and that this function is exerted through its association with Spt4 and Pol II.

  8. he Paf1 (zeige PEX2 Proteine) complex (Paf1C) and Tat-SF1, two factors implicated previously in elongation control, collaborate with DSIF (zeige SUPT5H Proteine) to facilitate efficient elongation

Mouse (Murine) Suppressor of Ty 4 Homolog 1 (S. Cerevisiae) (SUPT4H1) Interaktionspartner

  1. reduction of SUPT4H in mouse brains is associated with decreased HTT (zeige HTT Proteine) protein aggregation, and in R6/2 mice, also with prolonged lifespan and delay of the motor impairment that normally develops in these animals.

  2. our findings indicate that Spt4 and Spt5 (zeige SUPT5H Proteine) have essential functions in the DNA repair phase of immunoglobulin class switch recombination.

  3. These findings indicate that Supt4h is differentially required for expression of the mutant Htt (zeige HTT Proteine) allele in mouse striatal neurons.

Suppressor of Ty 4 Homolog 1 (S. Cerevisiae) (SUPT4H1) Protein Überblick

Protein Überblick

This gene encodes the small subunit of DRB (5,6-dichloro-1-beta-d-ribofuranosylbenzimidazole) sensitivity-inducing factor (DSIF) complex, which regulates mRNA processing and transcription elongation by RNA polymerase II. The encoded protein is localized to the nucleus and interacts with the large subunit (SUPT5H) to form the DSIF complex. Related pseudogenes have been identified on chromosomes 2 and 12. Alternatively spliced transcript variants have been found for this gene.

Genbezeichner und Symbole assoziert mit SUPT4H1

  • CG12372 gene product from transcript CG12372-RA (spt4)
  • Protein SPT-4 (spt-4)
  • suppressor of Ty 4 homolog 1 (supt4h1)
  • suppressor of Ty 4 homolog 1 (S. cerevisiae) (SUPT4H1)
  • suppressor of Ty 4 homolog 1 (S. cerevisiae) (Supt4h1)
  • suppressor of Ty 4A (Supt4a)
  • Zn-finger protein (SPT4)
  • 142904_at Protein
  • AL022777 Protein
  • CG12372 Protein
  • dDSIF Protein
  • Dmel\\CG12372 Protein
  • DSIF Protein
  • dspt4 Protein
  • l(2)k05316 Protein
  • Spt4 Protein
  • SPT4H Protein
  • Supt4h Protein
  • Supt4h1 Protein
  • Supt4h1a Protein
  • Supt4h2 Protein

Bezeichner auf Proteinebene für SUPT4H1

CG12372-PA , DSIF , spt4-PA , DRB sensitivity-inducing factor small subunit , DSIF small subunit , transcription elongation factor SPT4 , DRB sensitivity-inducing factor 14 kDa subunit , DSIF p14 , small hSpt4 subunit , suppressor of Ty 4 homolog 1 , suppressor of Ty 4 homolog 2 , DRB sensitivity-inducing factor small subunit 1 , DSIF small subunit 1 , transcription elongation factor SPT4 1 , transcription elongation factor SPT4-A , hypothetical protein

GENE ID SPEZIES
36387 Drosophila melanogaster
175172 Caenorhabditis elegans
734253 Xenopus laevis
6827 Homo sapiens
616425 Bos taurus
287608 Rattus norvegicus
100190855 Pongo abelii
20922 Mus musculus
3636395 Candida albicans SC5314
Ausgewählte Anbieter für Suppressor of Ty 4 Homolog 1 (S. Cerevisiae) Proteine (SUPT4H1)
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