anti-Stromal Interaction Molecule 2 (Stim2) Antikörper

Stim2 is a member of the stromal interaction molecule (STIM) family and likely arose, along with related family member STIM1, from a common ancestral gene. Zusätzlich bieten wir Ihnen Stim2 Proteine (8) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
Stim2 57620 Q9P246
Stim2 116873 P83093
Stim2 117087  
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Top anti-Stim2 Antikörper auf antikoerper-online.de

Showing 10 out of 72 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB Host: Rabbit Target Name: Stim2 Sample Type: Mouse Pancreas lysates Antibody Dilution: 1.0ug/ml 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB Formalin fixed, paraffin embedded human kidney tissue stained with STIM2 Antibody (N-term) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of STIM2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. Western blot analysis of STIM2 Antibody (N-term) in UM cell line lysates (35ug/lane). This demonstrates the STIM2 antibody detected the STIM2 protein (arrow 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert WB 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$368.50
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Human Kaninchen Unkonjugiert EIA, IHC (p), WB   0.1 mg Anmelden zum Anzeigen 12 bis 15 Tage
$375.38
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Human Kaninchen Unkonjugiert EIA, IHC (p), WB   0.1 mg Anmelden zum Anzeigen 10 bis 12 Tage
$375.38
Details
Human Kaninchen Unkonjugiert IHC (p), WB Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with STIM2 antibody ABIN213834 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$451.00
Details
Human Kaninchen Unkonjugiert IHC (p), WB STIM2 Antibody (N-term) (ABIN656476) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert IHC (p), WB 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
$500.50
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Human Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert IHC (p), ELISA, WB Human Liver (formalin-fixed, paraffin-embedded) stained with STIM2 antibody ABIN461903 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Pancreas (formalin-fixed, paraffin-embedded) stained with STIM2 antibody ABIN461903 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$451.00
Details

Stim2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Human ,
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Mouse (Murine)


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Rat (Rattus)


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Am meisten referenzierte anti-Stim2 Antikörper

  1. Human Polyclonal Stim2 Primary Antibody für IHC, ELISA - ABIN1003212 : Luik, Lewis: New insights into the molecular mechanisms of store-operated Ca2+ signaling in T cells. in Trends in molecular medicine 2007 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal Stim2 Primary Antibody für IHC, ELISA - ABIN1003213 : Spassova, Soboloff, He, Xu, Dziadek, Gill: STIM1 has a plasma membrane role in the activation of store-operated Ca(2+) channels. in Proceedings of the National Academy of Sciences of the United States of America 2006 (PubMed)
    Show all 4 Pubmed References

Weitere Antikörper gegen Stim2 Interaktionspartner

Human Stromal Interaction Molecule 2 (Stim2) Interaktionspartner

  1. The STIM2 protein play important roles in TGF-beta (zeige TGFB1 Antikörper)-induced EMT (zeige ITK Antikörper) and these effects are related to both store-operated calcium entry and non-store-operated calcium entry.

  2. What is less clear is how the spatial and temporal spread of intracellular Ca(2 (zeige CA2 Antikörper)+) is shaped and regulated by differential expression of the individual SOCE genes and their splice variants, their heteromeric combinations and pre- and posttranslational modifications. This review focuses on principle mechanisms regulating expression, splicing, and targeting of Ca(2 (zeige CA2 Antikörper)+) release-activated Ca(2 (zeige CA2 Antikörper)+) (CRAC) channels.

  3. While STIM1 (zeige STIM1 Antikörper) is a full Orai1 (zeige ORAI1 Antikörper)-agonist, leucine-replacement of this crucial residue in STIM2 endows it with partial agonist properties, which may be critical for limiting Orai1 (zeige ORAI1 Antikörper) activation stemming from its enhanced sensitivity to store-depletion

  4. STIM2.1 cannot activate Orai1 (zeige ORAI1 Antikörper) due to splicing in residues within the channel-activating domain (CAD (zeige CAD Antikörper)). STIM2.1 confers a calcium dependent dominant-negative function on both STIM1 (zeige STIM1 Antikörper) and STIM2 (STIM2.2). Affinity of the STIM2.1 calmodulin binding site within the CAD (zeige CAD Antikörper) domain is increased compared to STIM2.2.

  5. STIM2 enhances receptor-stimulated Ca(2 (zeige CA2 Antikörper)) signaling by promoting recruitment of STIM1 (zeige STIM1 Antikörper) to the endoplasmic reticulum-plasma membrane junctions.

  6. STIM2beta does not by itself strongly bind Orai1 (zeige ORAI1 Antikörper), it is recruited to Orai1 (zeige ORAI1 Antikörper) channels by forming heterodimers with other STIM isoforms.

  7. Imin channels are regulated by STIM2, TRPC3 (zeige TRPC3 Antikörper)-containing INS (zeige INS Antikörper) channels are induced by STIM1 (zeige STIM1 Antikörper), and TRPC1 (zeige TRPC1 Antikörper)-composed Imax channels are activated by both STIM1 (zeige STIM1 Antikörper) and STIM2.

  8. The higher amplitude of store-operated Ca2 (zeige CA2 Antikörper)+ entry was associated to the over-expression for Stim2, Orai2 (zeige ORAI2 Antikörper)-3, and TRPC1 (zeige TRPC1 Antikörper) while Stim2 levels remained constant and Stim1 (zeige STIM1 Antikörper), Orai1 (zeige ORAI1 Antikörper), Orai3 (zeige ORAI3 Antikörper), TRPC1 (zeige TRPC1 Antikörper) and TRPC4 (zeige TRPC4 Antikörper) proteins were over-expressed in primary myelofibrosis.

  9. the reciprocal shift in transient receptor potential channel 1 (TRPC1 (zeige TRPC1 Antikörper)) and stromal interaction molecule 2 (STIM2) contributes to Ca2 (zeige CA2 Antikörper)+ remodeling and cancer hallmarks in colorectal carcinoma cells

  10. STIM2 is highly expressed and controls store-operated Ca(2 (zeige CA2 Antikörper)+) entry in human melanoma. The invasive and migratory potential of melanoma cells was reduced upon silencing of STIM2.

Mouse (Murine) Stromal Interaction Molecule 2 (Stim2) Interaktionspartner

  1. neutrophil cytokine production required STIM2, but not STIM1 (zeige STIM1 Antikörper), at least in part as a result of redox regulation of cytokine gene expression

  2. Expression of STIM2 protein rescued CaMKII (zeige CAMK2G Antikörper) activity and protected mushroom spines from Abeta42 oligomer toxicity in vitro and in vivo.

  3. SOCE blockers or ablation of STIM1 (zeige STIM1 Antikörper), STIM2, or Orai1 (zeige TMEM132A Antikörper) severely impaired nucleotide-induced migration and phagocytosis in microglia.

  4. The data from this study indicate that upregulation of STIM2 and Orai2 (zeige ORAI2 Antikörper) is involved in the phenotypic transition of pulmonary arterial smooth muscle cells from a contractile state to a proliferative state.

  5. STIM1 (zeige STIM1 Antikörper), STIM2, and CRAC channel function play distinct but synergistic roles in CD4 (zeige CD4 Antikörper)+ and CD8 (zeige CD8A Antikörper)+ T cells during antiviral immunity

  6. STIM2 deficiency significantly delays onset and attenuates the clinical course of experimental allergic encephalitis.

  7. Using mice lacking STIM1 (zeige STIM1 Antikörper) and its homologue STIM2, authors find that store-operated calcium entry in CD8 (zeige CD8A Antikörper)(+) T cells is required to prevent the engraftment of melanoma and colon carcinoma cells and to control tumour growth.

  8. STIM1 (zeige STIM1 Antikörper) and STIM2-mediated store-operated Ca2 (zeige CA2 Antikörper)+ influx, leading to efficient activation of NFAT (zeige NFATC1 Antikörper) (nuclear factor of activated T cells), is critical for the postselection maturation of agonist-selected T cells.

  9. STIM1 (zeige STIM1 Antikörper) and STIM2 protein deficiency in T lymphocytes underlies development of the exocrine gland autoimmune disease, Sjogren's syndrome.

  10. show that endoplasmic reticulum calcium sensors STIM1 (zeige STIM1 Antikörper)- and STIM2-induced store-operated Ca(2 (zeige CA2 Antikörper)+) influx is critical for B cell regulatory function

Stim2 Antigen-Profil

Protein Überblick

This gene is a member of the stromal interaction molecule (STIM) family and likely arose, along with related family member STIM1, from a common ancestral gene. The encoded protein functions to regulate calcium concentrations in the cytosol and endoplasmic reticulum, and is involved in the activation of plasma membrane Orai Ca(2+) entry channels. This gene initiates translation from a non-AUG (UUG) start site. A signal peptide is cleaved from the resulting protein. Multiple transcript variants result from alternative splicing.

Genbezeichner und Symbole assoziert mit Stim2

  • stromal interaction molecule 2 (STIM2) Antikörper
  • stromal interaction molecule 2 (stim2) Antikörper
  • stromal interaction molecule 2 (Stim2) Antikörper
  • STIM2 Antikörper

Bezeichner auf Proteinebene für Stim2

stromal interaction molecule 2

GENE ID SPEZIES
100083707 Ornithorhynchus anatinus
100471703 Ailuropoda melanoleuca
100566248 Anolis carolinensis
422799 Gallus gallus
461155 Pan troglodytes
541299 Bos taurus
694980 Macaca mulatta
733739 Xenopus (Silurana) tropicalis
100540015 Meleagris gallopavo
57620 Homo sapiens
116873 Mus musculus
117087 Rattus norvegicus
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