anti-Sterile alpha Motif and Leucine Zipper Containing Kinase AZK (ZAK) Antikörper

ZAK is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM).

Alle Antikörper anzeigen Gen GeneID UniProt
Anti-Ratte ZAK ZAK 311743  
ZAK 51776 Q9NYL2
ZAK    
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Showing 10 out of 26 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IF, ELISA, WB 100 μL Anmelden zum Anzeigen 11 bis 14 Tage
565,71 €
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Human Maus Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 11 bis 14 Tage
635,55 €
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Human Kaninchen Unkonjugiert IHC, ELISA, WB IHC analysis of FFPE human hepatocarcinoma tissue stained with the ZAK antibody Western blot analysis of ZAK antibody and HepG2 lysate. There are 3 isoforms of ZAK, visualized at ~91, 51 and 35 kDa. 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
417,74 €
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Human Kaninchen Unkonjugiert IHC (p), WB Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Anmelden zum Anzeigen 11 bis 14 Tage
501,70 €
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Human Maus Alkaline Phosphatase (AP) ICC, ELISA, WB   100 μL Anmelden zum Anzeigen 11 bis 14 Tage
1.098,26 €
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Human Maus APC ICC, ELISA, WB   100 μL Anmelden zum Anzeigen 11 bis 14 Tage
1.098,26 €
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Human Maus Biotin ICC, ELISA, WB   100 μL Anmelden zum Anzeigen 11 bis 14 Tage
1.098,26 €
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Human Maus FITC ICC, ELISA, WB   100 μL Anmelden zum Anzeigen 11 bis 14 Tage
1.098,26 €
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Human Maus PE ICC, ELISA, WB   100 μL Anmelden zum Anzeigen 11 bis 14 Tage
1.098,26 €
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Human Kaninchen Alkaline Phosphatase (AP) IHC, ELISA, WB   200 μL Anmelden zum Anzeigen 11 bis 14 Tage
1.203,02 €
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ZAK Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Human ,
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,
, , , , ,
Mouse (Murine)


Weitere Antikörper gegen ZAK Interaktionspartner

Human Sterile alpha Motif and Leucine Zipper Containing Kinase AZK (ZAK) Interaktionspartner

  1. Gene set enrichment analysis disclosed a significant correlation between ZAK+ colorectal premalignant lesions and gene sets belonging to the MAPK/ERK (zeige MAPK1 Antikörper) and motility-related signaling pathways of the reactome database, strongly suggesting that ZAK induces such pro-tumoral reaction cascades in human cancers.

  2. Recessive mutations in the kinase ZAK - novel cause of congenital myopathy.

  3. ZAK is a key player in mammalian limb patterning in humans and mice.

  4. ZAK kinase isoform TV1 is preferentially upregulated in gastric tumours and cell lines relative to normal samples. This pattern is also observed in colorectal, bladder and breast cancers.

  5. The long non-coding RNA URHC promotes cell proliferation and inhibits apoptosis by repressing ZAK expression through inactivation of the ERK/MAPK (zeige MAPK1 Antikörper) pathway.

  6. we report that sorafenib suppresses UV-induced apoptosis specifically by inhibiting c-jun (zeige JUN Antikörper)-NH(2)-kinase (JNK (zeige MAPK8 Antikörper)) activation through the off-target inhibition of leucine zipper and sterile alpha motif-containing kinase (ZAK)

  7. MRK (zeige ICK Antikörper) is a novel RhoC (zeige RHOC Antikörper) effector that controls LPA (zeige APOA Antikörper)-stimulated cell invasion at least in part by regulating myosin dynamics, ERK (zeige EPHB2 Antikörper) and p38 (zeige CRK Antikörper)

  8. The genes identified KTN1 (zeige KTN1 Antikörper), ROCK1 (zeige ROCK1 Antikörper), and ZAK may be responsible for loss of cellular homeostasis in giant cells tumors of bone

  9. decrease of lung cancer cell proliferation by ZAK may involve the ERK (zeige EPHB2 Antikörper) and JNK (zeige MAPK8 Antikörper) pathways via an AP-1 (zeige FOSB Antikörper) transcription factor.

  10. In this study, by applying a novel method, we have identified the phosphorylation sites in human MSK1 mitogen- and stress-activated protein kinase 1 (zeige RPS6KA5 Antikörper), and show that MRK (zeige ICK Antikörper)-beta could also activate MSK1 (zeige RPS6KA5 Antikörper) through direct interaction.

ZAK Antigen-Profil

Protein Überblick

This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Genbezeichner und Symbole assoziert mit ZAK

  • sterile alpha motif and leucine zipper containing kinase AZK (Zak) Antikörper
  • sterile alpha motif and leucine zipper containing kinase AZK (ZAK) Antikörper
  • sterile alpha motif and leucine zipper containing kinase AZK (AT5G11850) Antikörper
  • AZK Antikörper
  • F14F18.20 Antikörper
  • F14F18_20 Antikörper
  • MLK7 Antikörper
  • mlklak Antikörper
  • MLT Antikörper
  • MLTK Antikörper
  • MRK Antikörper
  • pk Antikörper
  • RGD1561394 Antikörper
  • ZAK Antikörper

Bezeichner auf Proteinebene für ZAK

mitogen-activated protein kinase kinase kinase MLT , sterile alpha motif and leucine zipper containing kinase AZK , MLK-related kinase , HCCS-4 , MLK-like mitogen-activated protein triple kinase , human cervical cancer suppressor gene 4 protein , mixed lineage kinase 7 , mixed lineage kinase with a leucine zipper and a sterile alpha motif , mixed lineage kinase-related kinase MRK-beta

GENE ID SPEZIES
311743 Rattus norvegicus
424149 Gallus gallus
519251 Bos taurus
51776 Homo sapiens
831058 Arabidopsis thaliana
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