Squalene Epoxidase (SQLE) ELISA Kits

Squalene epoxidase catalyzes the first oxygenation step in sterol biosynthesis and is thought to be one of the rate-limiting enzymes in this pathway.. Zusätzlich bieten wir Ihnen Squalene Epoxidase Antikörper (26) und Squalene Epoxidase Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
SQLE 6713 Q14534
SQLE 20775 P52019
SQLE 29230 P52020
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Top Squalene Epoxidase ELISA Kits auf antikoerper-online.de

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Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 0.118 ng/mL 0.312-20 ng/mL 96 Tests Anmelden zum Anzeigen 13 bis 16 Tage
875,63 €
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Maus
  96 Tests Anmelden zum Anzeigen 13 bis 17 Tage
788,70 €
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Ratte
  96 Tests Anmelden zum Anzeigen 13 bis 17 Tage
788,70 €
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Weitere ELISA Kits für Squalene Epoxidase Interaktionspartner

Human Squalene Epoxidase (SQLE) Interaktionspartner

  1. Both HMGCR (zeige HMGCR ELISA Kits) and SQLE promoters have two SREs that may act as a homing region to attract a single SREBP-2 (zeige SREBF2 ELISA Kits) homodimer.

  2. Higher Gleason grade was associated with lower LDLR (zeige LDLR ELISA Kits) expression, lower SOAT1 (zeige SOAT1 ELISA Kits) and higher SQLE expression. Besides high SQLE expression, cancers that became lethal despite primary treatment were characterized by low LDLR (zeige LDLR ELISA Kits) expression (odds ratio for highest versus lowest quintile, 0.37; 95% CI 0.18-0.76) and by low SOAT1 (zeige SOAT1 ELISA Kits) expression (odds ratio, 0.41; 95% CI 0.21-0.83).

  3. Data indicate that microRNA miR (zeige MLXIP ELISA Kits)-133b-dependent squalene epoxidase (SQLE) plays a critical role in the potential metastasis mechanisms in esophageal squamous cell carcinoma (ESCC).

  4. our results pinpoint SQLE as a bona fide metabolic oncogene (zeige RAB1A ELISA Kits) by amplification, and as a therapeutic target in BC. These findings could have implications in other cancer types.

  5. this study have identified a Squalene Monooxygenase region integrally associated with the endoplasmic reticulum membrane that is likely to interact with cholesterol or respond to cholesterol-induced membrane effects.

  6. overexpression of SQLE in HCC (zeige FAM126A ELISA Kits) cells promoted cell proliferation and migration, while downregulation of SQLE inhibited the tumorigenicity of Hepatocellular carcinoma cells in vitro and in vivo.

  7. Data suggest that unsaturated fatty acids (oleate; oleoyl-CoA) stabilize SM/SQLE (which catalyzes 1st oxygenation step in cholesterol synthesis) most likely via inhibition of poly-ubiquitination by MARCH6 (membrane-associated ring finger (zeige PCGF1 ELISA Kits) [C3HC4] 6).

  8. MARCH6 and squalene monooxygenase (SM) physically interact, and consistent with MARCH6 acting as an E3 ligase, its overexpression reduces SM abundance in a RING-dependent manner.

  9. A cDNA library consisting of 220 upregulated genes in tumour tissue was established and named as LSCC. Differential expression was confirmed in five of these genes, including IGFBP5 (zeige IGFBP5 ELISA Kits), SQLE, RAP2B (zeige RAP2B ELISA Kits), CLDN1 (zeige CLDN1 ELISA Kits), and TBL1XR1 (zeige TBL1XR1 ELISA Kits).

  10. Distant metastasis-free survival in stage I/II breast cancer cases was significantly inversely related to SQLE mRNA in multivariate Cox (zeige COX8A ELISA Kits) analysis in two independent patient cohorts of 160 patients each

Mouse (Murine) Squalene Epoxidase (SQLE) Interaktionspartner

  1. Squalene epoxidase is a strong positional candidate gene for obesity, using squantitative trait locus studies.

  2. results demonstrate critical dependence of a 205 bp region for sterol dependent regulation of squalene epoxidase & uncover a possible framework for SREBP-promoter interaction, including a potent synergy with NF-Y that may be of principal importance.

  3. Requires a redox partner, but cytochrome p450 reductase (zeige POR ELISA Kits) is not the only microsomal reductase that will serve this purpose.

Squalene Epoxidase (SQLE) Antigen-Profil

Beschreibung des Gens

Squalene epoxidase catalyzes the first oxygenation step in sterol biosynthesis and is thought to be one of the rate-limiting enzymes in this pathway.

Genbezeichner und Symbole assoziert mit Squalene Epoxidase (SQLE) ELISA Kits

  • squalene epoxidase (SQLE) Antikörper
  • squalene epoxidase (ANI_1_450034) Antikörper
  • squalene epoxidase (AOR_1_1218114) Antikörper
  • squalene epoxidase (CC1G_03987) Antikörper
  • squalene epoxidase (BDBG_08449) Antikörper
  • squalene epoxidase (MCYG_02365) Antikörper
  • squalene epoxidase (TERG_05717) Antikörper
  • squalene epoxidase (Sqle) Antikörper
  • AI323792 Antikörper
  • An03g03770 Antikörper
  • AO090701000685 Antikörper

Bezeichner auf Proteinebene für Squalene Epoxidase (SQLE) ELISA Kits

squalene epoxidase , squalene monooxygenase , SE

GENE ID SPEZIES
100067615 Equus caballus
4980366 Aspergillus niger CBS 513.88
5995549 Aspergillus oryzae RIB40
6007557 Coprinopsis cinerea okayama7130
8508601 Ajellomyces dermatitidis SLH14081
9226506 Arthroderma otae CBS 113480
10376061 Trichophyton rubrum CBS 118892
100125351 Ovis aries
6713 Homo sapiens
608021 Canis lupus familiaris
100113409 Sus scrofa
526535 Bos taurus
20775 Mus musculus
29230 Rattus norvegicus
420335 Gallus gallus
Ausgewählte Anbieter für Squalene Epoxidase (SQLE) ELISA Kits
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