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Probable transcription factor, which may be involved in spermatogenesis and oogenesis (By similarity).. Zusätzlich bieten wir Ihnen SOHLH2 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.
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Cow (Bovine) Polyclonal SOHLH2 Primary Antibody für WB - ABIN2781042
Rual, Venkatesan, Hao, Hirozane-Kishikawa, Dricot, Li, Berriz, Gibbons, Dreze, Ayivi-Guedehoussou, Klitgord, Simon, Boxem, Milstein, Rosenberg, Goldberg, Zhang, Wong, Franklin, Li, Albala, Lim et al.: Towards a proteome-scale map of the human protein-protein interaction network. ... in Nature 2005
Human Polyclonal SOHLH2 Primary Antibody für IF (p), IHC (p) - ABIN1713906
Ding, Wang, Wu, Zhao, Zhang, Li: Protection of Murine Spermatogenesis Against Ionizing Radiation-Induced Testicular Injury by a Green Tea Polyphenol. in Biology of reproduction 2014
Results identified MMP9 (zeige MMP9 Antikörper) as a novel target for transcriptional inactivation by Sohlh2 and demonstrated that the Sohlh2 downregulation of MMP9 (zeige MMP9 Antikörper) is critical for inhibiting human ovarian cancer cell invasion.
The polymorphisms rs1328626 and rs6563386 of the SOHLH2 gene would be the genetic risk factors for nonobstructive azoospermia in the Chinese population. The SNP rs1328641 might influence testes development in the NOA (zeige DLAT Antikörper) patients.
Low Sohlh2 expression is associated with ovarian cancer.
Our identification of novel variants in the SOHLH2 gene, in women with POF (zeige POF1B Antikörper) of both Chinese and Serbian origin, strongly suggests an important role for SOHLH2 in human POF (zeige POF1B Antikörper) etiology.
SOHLH2 is critical for the formation of synaptonemal complexes.
Sohlh2 may inhibit oocyte apoptosis via c-kit (zeige KIT Antikörper)/PI3K/Akt (zeige AKT1 Antikörper)/Foxo3a (zeige FOXO3 Antikörper) signalling pathway
SOHLH1 (zeige SOHLH1 Antikörper) and SOHLH2 were able to directly and cooperatively repress STRA8 (zeige STRA8 Antikörper) expression in cell lines in vitro through binding to its promoter.
Our findings suggest that an SOHLH2/SOHLH1 (zeige SOHLH1 Antikörper)/SP1 (zeige SP1 Antikörper) ternary complex autonomously and cooperatively regulates Sohlh1 (zeige SOHLH1 Antikörper) gene transcription through juxtaposed E- and GC-boxes during early spermatogenesis and oogenesis.
Effects of BMP4 (zeige BMP4 Antikörper) on mouse primordial follicle growth were assayed by follicle count and TUNEL labeling. The expression of phospho-SMAD1 (zeige SMAD1 Antikörper)/5/8, Sohlh2, and c-kit (zeige KIT Antikörper) were measured by immunohistochemistry, RT-PCR, and Western blotting.
SOHLH1 (zeige SOHLH1 Antikörper) and SOHLH2 directly stimulate Kit transcription in postnatal spermatogonia, thus activating the signaling involved in spermatogonia differentiation and spermatogenetic progression.
Data suggest that a dynamic DNA CpG methylation in Sohlh2 and Figlalpha promoters, but not in the intron and exon sequences, is linked to regulation of gene expression, even though CpG islands are also present in their introns or exons.
SOHLH1 (zeige SOHLH1 Antikörper) and SOHLH2 suppress genes involved in spermatogonial stem cell maintenance, and induce genes important for spermatogonial differentiation.
The expression pattern of SOHLH2 suggests that it may be a critical regulator of early germ cell development.
Sohlh2 is a critical factor for maintenance and differentiation of the oocyte during early oogenesis
Probable transcription factor, which may be involved in spermatogenesis and oogenesis (By similarity).
spermatogenesis and oogenesis specific basic helix-loop-helix 2
, spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2-like
, spermatogenesis associated 28
, spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2