anti-Sperm Acrosome Associated 1 (SPACA1) Antikörper

The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Zusätzlich bieten wir Ihnen Sperm Acrosome Associated 1 Proteine (6) und Sperm Acrosome Associated 1 Kits (3) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
SPACA1 81833 Q9HBV2
SPACA1 67652 Q9DA48
SPACA1 614884 Q2YDG7
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Showing 10 out of 25 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB Immunohistochemistry analysis in Formalin Fixed, Paraffin Embedded Human testis tissue stained with SACA1 antibody (N-term) Cat.-AP53788PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SACA1 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. Western blot analysis in 293 cell line lysates (35 ug/lane) using SACA1 Antibody (N-term) Cat.-No AP53788PU-N. This demonstrates the SACA1 antibody detected the SACA1 protein (arrow). 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Human Kaninchen Unkonjugiert WB WB Suggested Anti-SPACA1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: NCI-H226 cell lysate WB Suggested Anti-SPACA1  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: NCI-H226 cell lysate  SPACA1 is supported by BioGPS gene expression data to be expressed in NCIH226 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert IHC, IHC (p) Immunohistochemistry: SPACA1 Antibody [NBP1-80792] - Staining of human testis shows strong cytoplasmic positivity in spermatids and spermatozoa. 0.1 mL Anmelden zum Anzeigen 5 bis 8 Tage
335,00 €
Details
Maus Kaninchen Unkonjugiert IF, WB 100 μL Anmelden zum Anzeigen 5 bis 7 Tage
413,81 €
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Human Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
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Rind (Kuh) Meerschweinchen Unkonjugiert IHC (fro), WB   0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Human Kaninchen Unkonjugiert FACS, IHC, WB   200 μL Anmelden zum Anzeigen 11 bis 14 Tage
941,11 €
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Human Kaninchen Biotin FACS, IHC, ELISA, WB   200 μL Anmelden zum Anzeigen 11 bis 14 Tage
1.203,02 €
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Human Kaninchen FITC FACS, IHC, ELISA, WB   200 μL Anmelden zum Anzeigen 11 bis 14 Tage
1.203,02 €
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Human Kaninchen PE FACS, IHC, ELISA, WB   200 μL Anmelden zum Anzeigen 11 bis 14 Tage
1.203,02 €
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SPACA1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Human ,
, , ,

, , , , ,
Mouse (Murine)


Cow (Bovine)


Am meisten referenzierte anti-Sperm Acrosome Associated 1 Antikörper

  1. Human Polyclonal SPACA1 Primary Antibody für IHC, IHC (p) - ABIN4355473 : Longepied, Saut, Aknin-Seifer, Levy, Frances, Metzler-Guillemain, Guichaoua, Mitchell: Complete deletion of the AZFb interval from the Y chromosome in an oligozoospermic man. in Human reproduction (Oxford, England) 2010 (PubMed)
    Zeige alle 2 Referenzen für 4355473

  2. Cow (Bovine) Polyclonal SPACA1 Primary Antibody für IHC (fro), WB - ABIN126105 : Hao, Wolkowicz, Shetty, Klotz, Bolling, Sen, Westbrook, Coonrod, Flickinger, Herr: SAMP32, a testis-specific, isoantigenic sperm acrosomal membrane-associated protein. in Biology of reproduction 2002 (PubMed)

Weitere Antikörper gegen Sperm Acrosome Associated 1 Interaktionspartner

Human Sperm Acrosome Associated 1 (SPACA1) Interaktionspartner

  1. Spaca1 role in male infertility.Distribution of SPACA1 in the sperm affects the outcomes of conventional in vitro fertilization.

  2. Human posterior head 20 (hPH20) and homo sapiens sperm acrosome associated 1 (hSPACA1) immunocontraceptive epitopes reduced fertility in male/female mice.

  3. SAMP32 was associated with the inner acrosomal membrane and recombinant SAMP32 reacted with serum from an infertile man suggesting that it is isoantigenic

Mouse (Murine) Sperm Acrosome Associated 1 (SPACA1) Interaktionspartner

  1. SPACA1-deficient male mice are infertile with abnormally shaped sperm heads reminiscent of globozoospermia.

Sperm Acrosome Associated 1 (SPACA1) Antigen-Profil

Protein Überblick

The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from infertile males. Furthermore, antibodies generated against the recombinant protein block in vitro fertilization. This protein localizes to the acrosomal membrane of spermatids and mature spermatozoa where it is thought to play a role in acrosomal morphogenesis and in sperm-egg binding and fusion, respectively.

Genbezeichner und Symbole assoziert mit SPACA1

  • sperm acrosome associated 1 (SPACA1) Antikörper
  • sperm acrosome associated 1 (Spaca1) Antikörper
  • 1700124L11Rik Antikörper
  • 4930540L03Rik Antikörper
  • SAMP32 Antikörper

Bezeichner auf Proteinebene für SPACA1

sperm acrosomal membrane-associated protein 32 , sperm acrosome membrane-associated protein 1

GENE ID SPEZIES
81833 Homo sapiens
67652 Mus musculus
614884 Bos taurus
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