anti-Solute Carrier Family 6 (Neurotransmitter Transporter, Glycine), Member 5 (SLC6A5) Antikörper

SLC6A5 encodes a sodium- and chloride-dependent glycine neurotransmitter transporter. Zusätzlich bieten wir Ihnen SLC6A5 Proteine (7) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
SLC6A5 104245  
SLC6A5 9152 Q9Y345
SLC6A5 171148 P58295
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Top anti-SLC6A5 Antikörper auf antikoerper-online.de

Showing 10 out of 17 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-SLC6A5 Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>PANC1 cell lysate WB Suggested Anti-SLC6A5 <br /> Antibody Titration: 0.2-1 µg/mL <br /> Positive Control: PANC1 cell lysate <br /> SLC6A5 is supported by BioGPS gene expression data to be expressed in PANC1 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
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Rind (Kuh) Kaninchen Unkonjugiert IHC, WB 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
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Ratte Kaninchen Unkonjugiert IP, IHC, WB 50 μg Anmelden zum Anzeigen 1 bis 2 Tage
341,00 €
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Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
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Human Kaninchen Unkonjugiert ELISA, WB   50 μL Anmelden zum Anzeigen 11 bis 14 Tage
775,24 €
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Human Kaninchen Unkonjugiert WB   100 μL Anmelden zum Anzeigen 12 Days
261,90 €
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Human Maus Unkonjugiert ELISA, WB Western Blot detection against Immunogen (36.74 KDa) . 100 μg Anmelden zum Anzeigen 7 bis 8 Tage
369,60 €
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Ratte Kaninchen Unkonjugiert ELISA, WB   50 μg Anmelden zum Anzeigen 11 bis 14 Tage
792,70 €
Details
Fledermaus Kaninchen Unkonjugiert WB   50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
Details
Human Maus Unkonjugiert ELISA, WB Western Blot detection against Immunogen (37.11 KDa) . 50 μL Anmelden zum Anzeigen 7 bis 8 Tage
241,60 €
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SLC6A5 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
Mouse (Murine)


Human
,
,
Rat (Rattus)


Am meisten referenzierte anti-SLC6A5 Antikörper

  1. Rat (Rattus) Polyclonal SLC6A5 Primary Antibody für IP, IHC - ABIN1742533 : Sunagawa, Shimizu-Okabe, Kim, Kobayashi, Kosaka, Yanagawa, Matsushita, Okabe, Takayama: Distinct development of the glycinergic terminals in the ventral and dorsal horns of the mouse cervical spinal cord. in Neuroscience 2016 (PubMed)

Weitere Antikörper gegen SLC6A5 Interaktionspartner

Mouse (Murine) Solute Carrier Family 6 (Neurotransmitter Transporter, Glycine), Member 5 (SLC6A5) Interaktionspartner

  1. that the deletion of VIAAT (zeige SLC32A1 Antikörper) in GlyT2-Cre expressing neurons also strongly affects GABAergic transmission

  2. Results suggest that the excessive GAT-1 (zeige SLC6A1 Antikörper) and GlyT-1 (zeige GLYT1 Antikörper)/2 heterotransporter-mediated Glu (zeige GCG Antikörper) release, in the spinal cord of SOD1 (zeige SOD1 Antikörper)(G93A) mice, is due to the heterotransporter over-expression at the nerve terminal membrane, promoted by the excessive Glu (zeige GCG Antikörper) exocytosis

  3. Report that in the presence of a GlyT2 mechanism-based toxicity, reversible inhibitors might allow a tolerable balance between efficacy and toxicity.

  4. These alterations in the activities and expression profiles of the GlyTs suggest that the contributions of GlyT1 (zeige GLYT1 Antikörper) and GlyT2 to the regulation of extracellular glycine concentrations at glycinergic synapses changes during development.

  5. Data show that the GlyT2 protein is undetectable in homozygous mutants, indicating a null allele.

  6. In the first postnatal week, loss of the glycine transporter 2 is neither compensated by glycine de-novo synthesis nor by up-regulation of the GABAergic transmission in GlyT2(-/-) mice.

  7. These data indicate that the C-terminal PDZ (zeige INADL Antikörper)-ligand motif of GlyT2 plays an important role in transporter trafficking to and/or stabilization at synaptic sites.

  8. Glyt2-mediated release of glycine from axon terminals involves exocytosis triggered by intraterminal mitochondrial Ca2 (zeige CA2 Antikörper)+ ions.

  9. our results demonstrate the central role played by GlyT2 in determining inhibitory phenotype and therefore in the physiology and pathology of inhibitory circuits.

Human Solute Carrier Family 6 (Neurotransmitter Transporter, Glycine), Member 5 (SLC6A5) Interaktionspartner

  1. analysis of the human SLC6A5 (zeige SLC6A2 Antikörper) gene mutation associated with hyperekplexia

  2. Report that in the presence of a GlyT2 mechanism-based toxicity, reversible inhibitors might allow a tolerable balance between efficacy and toxicity.

  3. Constitutive endocytosis and turnover of the neuronal glycine transporter GlyT2 is dependent on ubiquitination of a C-terminal lysine cluster.

  4. A novel dominant hyperekplexia mutation Y705C alters trafficking and biochemical properties of the presynaptic glycine transporter GlyT2.

  5. This study firmly establishes the combination of missense, nonsense, frameshift, and splice site mutations in the GlyT2 gene as the second major cause of startle disease.

  6. A transgenic cell line is studied in which green fluorescent protein (GFP) is expressed under the control of the promoter for the glycine transporter GlyT2 during zebrafish development.

  7. Inspiratory-modulated neurons with pacemaker properties are present in the preBotzinger complex of newborn transgenic mice and express the glycine tranporter (GlyT)2 protein.

  8. SLC6A5 (zeige SLC6A2 Antikörper) mutations result in defective subcellular GlyT2 localization, decreased glycine uptake or both, with selected mutations affecting predicted glycine and Na+ binding sites.

  9. results are consistent with GLYT2 being a disease gene in human hyperekplexia

  10. SLC6A5 (zeige SLC6A2 Antikörper) gene is associated with schizophrenia.

SLC6A5 Antigen-Profil

Protein Überblick

This gene encodes a sodium- and chloride-dependent glycine neurotransmitter transporter. This integral membrane glycoprotein is responsible for the clearance of extracellular glycine during glycine-mediated neurotransmission. This protein is found in glycinergic axons and maintains a high presynaptic pool of neurotransmitter at glycinergic synapses. Mutations in this gene cause hyperekplexia\; a heterogenous neurological disorder characterized by exaggerated startle responses and neonatal apnea.

Genbezeichner und Symbole assoziert mit SLC6A5

  • solute carrier family 6 (neurotransmitter transporter, glycine), member 5 (SLC6A5) Antikörper
  • solute carrier family 6 (neurotransmitter transporter, glycine), member 5 (LOC100339626) Antikörper
  • solute carrier family 6 (neurotransmitter transporter, glycine), member 5 (Slc6a5) Antikörper
  • solute carrier family 6 (neurotransmitter transporter), member 5 (SLC6A5) Antikörper
  • solute carrier family 6 (neurotransmitter transporter), member 5 (Slc6a5) Antikörper
  • GLYT-2 Antikörper
  • GLYT2 Antikörper
  • HKPX3 Antikörper
  • NET1 Antikörper
  • prestin Antikörper
  • SLC6A5 Antikörper

Bezeichner auf Proteinebene für SLC6A5

solute carrier family 6 (neurotransmitter transporter, glycine), member 5 , sodium- and chloride-dependent glycine transporter 2-like , glyT-2 , glycine transporter 2 , sodium- and chloride-dependent glycine transporter 2 , solute carrier family 6 member 5

GENE ID SPEZIES
422974 Gallus gallus
466470 Pan troglodytes
612095 Canis lupus familiaris
704703 Macaca mulatta
100339626 Oryctolagus cuniculus
100431924 Pongo abelii
100585180 Nomascus leucogenys
104245 Mus musculus
9152 Homo sapiens
171148 Rattus norvegicus
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