Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
SLC35C1 encodes a GDP-fucose transporter that is found in the Golgi apparatus. Zusätzlich bieten wir Ihnen SLC35C1 Antikörper (8) und und viele weitere Produktgruppen zu diesem Protein an.
two Turkish siblings with a novel mutation in GDP-fucose transporter and features of congenital disorder of glycosylation IIc
Fx enzyme and GDP-L-Fuc (zeige FUT8 ELISA Kits) Tr overexpression in the tumur tissue of colorectal cancer (CRC (zeige CALR ELISA Kits)) patients suggests that GDP-L-Fuc (zeige FUT8 ELISA Kits) transport to the Golgi apparatus may be an important factor associated with increased alpha(1,6)fucosylation in CRC (zeige CALR ELISA Kits).
In the rare LAD (zeige DLD ELISA Kits)-II disease, the fucosylation of selectin ligands is disturbed, caused by mutations in SLC35C1, the gene that encodes a GDP-fucose transporter of the Golgi system. (Review)
the conserved glycine residues at positions 180 and 277 of SLC35C1 have significant impacts on lectin binding
In the GDP-fucose transporter a new single nucleotide deletion produced an open-reading frame shift & polypeptide truncation. Overexpression of the mutant protein in fibroblasts did not rescue fucosylation. The deletion ablated transporter activity.
Leukocyte adhesion deficiency II patients display dual defect in functoin ang Golgi expression of FUCT1.
the upregulation of GDP-Fuc Tr plays a pivotal role in increased fucosylation in hepatocellular carcinoma
Slc35c1(-/-) mice show strongly defective leukocyte trafficking but normal lymphocyte homing to the spleen, which may explain normal lymphocyte functions in LAD II.
Slc35c1 overexpression causes elevated N-linked fucosylation and disrupts embryonic patterning in a transporter activity dependent manner.
This gene encodes a GDP-fucose transporter that is found in the Golgi apparatus. Mutations in this gene result in congenital disorder of glycosylation type IIc. Multiple transcript variants encoding different isoforms have been found for this gene.
GDP-fucose transporter 1
, solute carrier family 35, member C1
, multispan transmembrane protein fuct1
, GDP-fucose transporter
, solute carrier family 35 member C1
, GDP-fucose transporter 1-like
, golgi GDP-fucose translocator