Solute Carrier Family 26, Member 3 Proteine (SLC26A3)

The protein encoded by SLC26A3 is a transmembrane glycoprotein that transports chloride ions across the cell membrane in exchange for bicarbonate ions. Zusätzlich bieten wir Ihnen SLC26A3 Antikörper (16) und SLC26A3 Kits (1) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
SLC26A3 1811 P40879
Ratte SLC26A3 SLC26A3 114629 Q924C9
SLC26A3 13487 Q9WVC8
Direkt bei antikoerper-online bestellen
  • +49 (0)241 95 163 153
  • +49 (0)241 95 163 155
  • Online bestellen
  • orders@antikoerper-online.de

Top SLC26A3 Proteine auf antikoerper-online.de

Showing 4 out of 12 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 56 bis 61 Tage
8.202,81 €
Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 56 bis 61 Tage
5.753,97 €
Details
HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
Details
HOST_Escherichia coli (E. coli) Human His tag   50 μg Anmelden zum Anzeigen 15 bis 16 Tage
324,76 €
Details

SLC26A3 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine)

Weitere Proteine zu Solute Carrier Family 26, Member 3 (SLC26A3) Interaktionspartnern

Zebrafish Solute Carrier Family 26, Member 3 (SLC26A3) Interaktionspartner

Human Solute Carrier Family 26, Member 3 (SLC26A3) Interaktionspartner

  1. Genetic variations of the SLC26A3 rs2108225 is associated with enhance the risk of ulcerative colitis.

  2. We report the first Tunisian case of SLC26A3 gene mutation in congenital chloride diarrhea. Our patient was homozygous for G187X mutation. Both parents were heterozygous for the same mutation.

  3. Expression of NHE3 and DRA was reduced with high tacrolimus levels and impaired renal function after intestinal transplantation.

  4. A variety of mutations in SLC26A3 are responsible for CCD (zeige RUNX2 Proteine). A total of 55 mutations in SLC26A3 have been reported

  5. Data demonstrate an upregulation of SLC26A3 via activation of the ERK1/2 pathway that may underlie potential antidiarrheal effects of Bifidobacterium sp.

  6. Efficacy of lactobacillus acidophilus or its secreted soluble factors in alleviating inflammation and inflammation-associated dysregulation of DRA activity could justify their therapeutic potential in inflammatory diarrheal diseases.

  7. The SLC26A3-NHERF4 (zeige PDZD3 Proteine) interaction was modulated by phosphorylation; serine 329 of NHERF4 (zeige PDZD3 Proteine)-PDZ3 played a critical role in modulating binding selectivity.

  8. few patients develop illnesses because of SLC26A3 mutations.

  9. Slc26a3 contributes to sulfate secretion via DIDS-senstive bicarbonate-sulfate exchange in addition to being the principal DIDS-resistant chloride-bicarbonate exchanger (zeige SLC4A2 Proteine).

  10. these data indicate that N-glycosylation of SLC26A3 is important for cell surface expression and for protection from proteolytic degradation that may contribute to the understanding of pathogenesis of congenital disorders of glycosylation.

Mouse (Murine) Solute Carrier Family 26, Member 3 (SLC26A3) Interaktionspartner

  1. This study showed that transepithelial sulfate fluxes across the mouse distal ileum demonstrating that DRA (and to a lesser extent, PAT1) secretes sulfate with significant implications for intestinal sulfate absorption and overall homeostasis.

  2. DRA surface expression was reduced partly via an increase in DRA endocytosis and a decrease in exocytosis

  3. Both PAT-1 and DRA significantly contribute to intestinal fluid absorption and enterocyte acid/base balance but are activated by different ion gradients.

  4. Data demonstrate an upregulation of SLC26A3 via activation of the ERK1/2 pathway that may underlie potential antidiarrheal effects of Bifidobacterium sp.

  5. Data indicate that solute carrier (zeige SERTAD2 Proteine) family 26, member 3 protein (Slc26a3) is expressed in male reproductive tract, and its expression pattern is related to the function.

  6. Deletion of DRA results in severely reduced colonic HCO3 (-) secretory rate, a loss of colonic fluid absorption, a lack of a firmly adherent mucus layer and a severely reduced colonic mucosal resistance to dextran sodium sulphate damage.

  7. Efficacy of lactobacillus acidophilus or its secreted soluble factors in alleviating inflammation and inflammation-associated dysregulation of DRA activity could justify their therapeutic potential in inflammatory diarrheal diseases.

  8. DRA mediates a predominance of the apical uptake of oxalate and Cl(-) absorbed in the small and large intestine of mice under short-circuit conditions.

  9. Endogenous and recombinant human/mouse Slc26a3 do not exhibit electrogenic 2Cl-/1HCO- exchange. Acute induction of Slc26a3 Cl-/HCO3- exchange is associated with secondary membrane potential changes representing homeostatic responses.

  10. This study showed a functionally active CFTR (zeige CFTR Proteine) is an absolute requirement for Slc26-mediated duodenal bicarbonate secretion, but not for Slc26-mediated fluid absorption.

SLC26A3 Protein Überblick

Protein Überblick

The protein encoded by this gene is a transmembrane glycoprotein that transports chloride ions across the cell membrane in exchange for bicarbonate ions. It is localized to the mucosa of the lower intestinal tract, particularly to the apical membrane of columnar epithelium and some goblet cells. The protein is essential for intestinal chloride absorption, and mutations in this gene have been associated with congenital chloride diarrhea.

Genbezeichner und Symbole assoziert mit SLC26A3

  • solute carrier family 26, member 3 (SLC26A3)
  • si:dkey-31f5.1 (si:dkey-31f5.1)
  • solute carrier family 26, member 3 (slc26a3)
  • solute carrier family 26 (anion exchanger), member 3 (SLC26A3)
  • solute carrier family 26 (anion exchanger), member 3 (Slc26a3)
  • solute carrier family 26, member 3 (Slc26a3)
  • 9030623B18Rik Protein
  • 9130013M11Rik Protein
  • AV376035 Protein
  • CLD Protein
  • Dra Protein
  • si:dkey-31f5.2 Protein
  • SLC26A3 Protein
  • zgc:136981 Protein

Bezeichner auf Proteinebene für SLC26A3

solute carrier family 26, member 3 , down-regulated in adenoma protein , chloride anion exchanger-like , chloride anion exchanger , down-regulated in adenoma , solute carrier family 26 member 3 , down-regulated in adenoma DRA

GENE ID SPEZIES
417700 Gallus gallus
472483 Pan troglodytes
563896 Danio rerio
563962 Danio rerio
701873 Macaca mulatta
100010561 Monodelphis domestica
100399461 Callithrix jacchus
100582611 Nomascus leucogenys
1811 Homo sapiens
114629 Rattus norvegicus
483261 Canis lupus familiaris
100170644 Sus scrofa
512856 Bos taurus
100008798 Oryctolagus cuniculus
13487 Mus musculus
Ausgewählte Anbieter für SLC26A3 Proteine (SLC26A3)
Haben Sie etwas anderes gesucht?