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SLC2A9 encodes a member of the SLC2A facilitative glucose transporter family. Zusätzlich bieten wir Ihnen SLC2A9 Antikörper (91) und und viele weitere Produktgruppen zu diesem Protein an.
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In liver-specific Glut9 knockout mice, inosine-induced hyperuricemia was not associated with hypertension despite partial renal deficiency.
intestinal uric acid transporter SLC2A9 has a role in early-onset metabolic syndrome in a mouse model
blocking GLUT9 expression during preimplantation development (zeige MTA2 ELISA Kits) had no effect on glucose transport or apoptosis but transfer of these embryos resulted in increased pregnancy loss, suggesting that GLUT9 is critical for early preimplantation development (zeige MTA2 ELISA Kits).
Characterize in more detail the transport properties of mouse GLUT9 and provide evidence that it functions as a urate uniporter.
Glut9 is a major regulator of urate homeostasis and its genetic inactivation induces hyperuricosuria and urate nephropathy.
This meta-analysis shows that the rs12510549, rs16890979, and rs1014290 polymorphisms of SLC2A9 protect against the development of gout in Caucasians and/or Asians.
The results of the study confirmed the presence of GLUT-1 (zeige SLC2A1 ELISA Kits), GLUT-4 (zeige SLC2A4 ELISA Kits) and GLUT-9 (zeige SLC2A6 ELISA Kits) proteins in the trophoblast from both, uncomplicated and diabetic pregnancies. In addition, insulin (zeige INS ELISA Kits) therapy may increase placental expression of GLUT-4 (zeige SLC2A4 ELISA Kits) and GLUT-9 (zeige SLC2A6 ELISA Kits), and partially GLUT-1 (zeige SLC2A1 ELISA Kits), in women with pregestational and gestational diabetes mellitus.
Meta-analysis. This study demonstrated that the genetic susceptibility for gout is associated with the SLC2A9 gene polymorphisms. Four of them except for the rs3733591 are protective SNPs in Caucasians, and rs16890979 and rs1014290 are protective SNPs in both Caucasians and Asians, while rs3733591 may be susceptibility SNP in Asians.
Each A-allele of the SLC2A9 rs7442295 was associated with 9% higher plasma urate and hazard ratios of 1.07 (1.01-1.14) for cancer incidence and 1.07 (1.02-1.13) for all-cause mortality.
The present proof-of-principle paper demonstrates that the multilocus profiles of ABCG2 (zeige ABCG2 ELISA Kits), SLC2A9 and SLC22A12 (zeige SLC22A12 ELISA Kits) increase susceptibility to asymptomatic hyperuricaemia, gout and tophi.
Immunostaining and highly-sensitive in situ hybridization was used to assess the distribution of UA transporters: GLUT9/URATv1, ABCG2 (zeige ABCG2 ELISA Kits), and URAT1 (zeige SLC22A12 ELISA Kits). Immunostaining for GLUT9 (zeige SLC2A6 ELISA Kits) was observed in ependymal cells, neurons, and brain capillaries. Immunostaining for ABCG2 (zeige ABCG2 ELISA Kits) was observed in the choroid plexus epithelium and brain capillaries, but not in ependymal cells. These results were validated by in situ hybridization.
The first genome-wide association study for serum uric acid level in Indians revealed association of SLC2A9, SLC22A11 (zeige SLC22A11 ELISA Kits) and ABCG2 (zeige ABCG2 ELISA Kits) gene variants at genome wide significance level in Type 2 diabetes patients.
the exon 9 of SLC2A9 gene 109C/T polymorphism is not associated with HUA and diabetes
Demonstrate a significant association between rs2231142 in the ABCG2 (zeige ABCG2 ELISA Kits) gene and gout and identified novel SNPs, c.881A>G and c.1002+78G>A, in the SLC2A9 gene that may be associated with gout in a Korean population.
GLUT9 (zeige SLC2A6 ELISA Kits) gene polymorphism predicts higher risk for cardiovascular diseases in patient diagnosed with hyperuricemia.
This gene encodes a member of the SLC2A facilitative glucose transporter family. Members of this family play a significant role in maintaining glucose homeostasis. The encoded protein may play a role in the development and survival of chondrocytes in cartilage matrices. Two transcript variants encoding distinct isoforms have been identified for this gene.
solute carrier family 2 (facilitated glucose transporter), member 9
, solute carrier family 2, member 9 protein
, Solute carrier family 2, facilitated glucose transporter member 9
, glucose transporter type 9
, human glucose transporter-like protein-9
, solute carrier family 2, facilitated glucose transporter member 9
, urate voltage-driven efflux transporter 1
, facilitated glucose transporter, type 9
, solute carrier family 2, member 9