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Proton oligopeptide cotransporter. Zusätzlich bieten wir Ihnen SLC15A4 Antikörper (12) und und viele weitere Produktgruppen zu diesem Protein an.
Under a dominant model the rs1385374 (TT+CT) SNP carried a higher risk of Systemic Lupus Erythematosus (SLE) than (CC). Under a codominant model the genotype frequencies of rs3765108 AG and rs7308691 AT were significantly higher in the SLE group than the control group. One SLC15A4 haplotype (TA), which consists of 2 SNPs (rs959989 and rs983492), was associated with SLE
Mutations in SLC15A4,a peptide transporter in NFkB signaling pathway, have been implicated in Systemic Lupus Erythematosus development in susceptible individuals.
Report role of SLC15A4 genetic variants in confering risk of systemic lupus erythematosus in Chinese population.
LNCaP expresses high levels of PEPT2 (zeige SLC15A2 ELISA Kits) and PHT1.PC-3 (zeige PCSK1 ELISA Kits) demonstrates strong expression of PEPT1 (zeige SLC15A1 ELISA Kits) and PHT1.
PEPT1,PEPT2, PHT1, and PHT2 are expressed in human nasal epithelium.
Significant associations were found for the single nucleotide polymorphism rs10847697 of SLC15A4 with discoid rash in patients with systemic lupus erythematosus
Slc15a4 is required for intact function of TLR9 (zeige TLR9 ELISA Kits)-expressing cells and for effective antibody isotype switching to IgG2c.
SLC15A4-mediated optimization of the endolysosomal state is integral to a Toll-like receptor 7 (zeige TLR7 ELISA Kits)-triggered, mTOR (zeige FRAP1 ELISA Kits)-dependent interferon regulatory factor 7 (zeige IRF7 ELISA Kits)-type I interferon (zeige IFNA ELISA Kits) circuit that leads to autoantibody production.
We found marked changes in protein expression and functional activity of PhT1 and PepT2 (zeige SLC15A2 ELISA Kits), the former predominating in adult and the latter in neonate
the feeble mutation (Slc15a4) affecting Plasmacytoid dendritic cells is dispensable for immunity during an acute infection; however, data show that feeble mice failed to control a chronic infection
results demonstrate pDCs and the production of type I IFNs by these cells are critical contributors to the pathogenesis of lupus-like autoimmunity in these models. IRF8 (zeige IRF8 ELISA Kits) and SLC15A4 may provide important targets for therapeutic intervention in human lupus
SLC15A4 promotes colitis through Toll-like receptor 9 (zeige TLR9 ELISA Kits) and NOD1 (zeige NOD1 ELISA Kits)-dependent innate immune responses.
The identification of the feeble mutation led to our subsequent observations that AP-3 (zeige AP3B1 ELISA Kits), as well as the BLOC-1 (zeige PLDN ELISA Kits) and BLOC-2 (zeige HPS6 ELISA Kits) are essential for plasmacytoid dendritic cells signaling through TLR7 (zeige TLR7 ELISA Kits) and TLR9 (zeige TLR9 ELISA Kits).
Proton oligopeptide cotransporter. Transports free histidine and certain di- and tripeptides (By similarity).
solute carrier family 15 member 4
, bZ1L10.1 (novel peptide transporter)
, solute carrier family 15, member 4
, peptide transporter 4
, solute carrier family 15 member 4-like
, peptide-histidine transporter 4
, peptide/histidine transporter 1