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Solute Carrier Family 13 Member 2 Proteine (SLC13A2)

facilitates sodium dependent transport of Krebs cycle intermediates including citrate, succinate, alpha-ketoglutarate, and oxaloacetate [RGD, Feb 2006].. Zusätzlich bieten wir Ihnen Solute Carrier Family 13 Member 2 Antikörper (29) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
SLC13A2 100508689  
SLC13A2 20500 Q9ES88
Ratte SLC13A2 SLC13A2 65202  
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Showing 4 out of 5 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 46 bis 51 Tage
5.743,80 €
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Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 46 bis 51 Tage
4.032,65 €
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HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
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HOST_Escherichia coli (E. coli) Human Unkonjugiert   50 μg Anmelden zum Anzeigen 6 bis 8 Tage
304,76 €
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SLC13A2 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
,
Mouse (Murine)

Weitere Proteine zu Solute Carrier Family 13 Member 2 (SLC13A2) Interaktionspartnern

Human Solute Carrier Family 13 Member 2 (SLC13A2) Interaktionspartner

  1. NaDC1 is present throughout the entire proximal tubule, but was not detected in kidney tumors.

  2. cyclophilin (zeige PPIA Proteine) isoform B is likely responsible for down-regulation of carrier expression by CsA (zeige ERCC8 Proteine) and that it does so via its chaperone activity on NaDC1 (by direct interaction) rather than its rotamase (zeige FKBP1B Proteine) activity.

  3. study concludes most of the naturally occurring nonsynonymous SNPs affect protein processing of NaDC1; several also affect functional properties; mutations are predicted to decrease transport activity

  4. This paper describes the cloning and functional characterization of the human Na(+)-coupled citrate transporter (NaCT).

  5. Data show that the sodium-dependent dicarboxylate co-transporter protein (zeige HNRNPU Proteine) 1 is located in renal proximal tubule lumenal membranes, and that the C-terminal sequence is required for delivery and targeting and may contain the signal sequence.

  6. The Ser (zeige SIGLEC1 Proteine) or Thr (zeige TRH Proteine) at position 509 is the most important determinant of functional differences in apparent affinity for substrate and cations. The cation and substrate binding sites are located in close proximity to one another.

Rabbit Solute Carrier Family 13 Member 2 (SLC13A2) Interaktionspartner

  1. Data show that NaDC1 F336C had increased transport activity due to an increased Vmax for succinate.

Mouse (Murine) Solute Carrier Family 13 Member 2 (SLC13A2) Interaktionspartner

  1. Slc26a6 (zeige SLC26A6 Proteine)-null mice exhibit increased renal and intestinal sodium-dependent succinate uptake, as well as urinary hyperoxaluria and hypocitraturia, but no change in urinary pH, indicating enhanced transport activity of NaDC-1.

  2. The acid-activated pathway mediating stimulation of kidney NaDC-1 activity requires a functional ET(B (zeige EDNRB Proteine)) receptor in vivo and in vitro.

  3. Substrate-dependent inward currents, measured using two-electrode voltage clamp, were similar for glutarate & succinate in Xenopus oocytes expressing mouse NaDC1. Currents evoked by glutarate in rabbit NaDC1 were about 5% of succinate-dependent currents.

  4. Sodium dicarboxylate cotransporter is involved in regulating levels of various Krebs cycle intermediates in the kidney, although impaired uptake of these intermediates does not significantly affect renal function under normal or ischemic stress.

Solute Carrier Family 13 Member 2 (SLC13A2) Protein Überblick

Protein Überblick

facilitates sodium dependent transport of Krebs cycle intermediates including citrate, succinate, alpha-ketoglutarate, and oxaloacetate

Genbezeichner und Symbole assoziert mit SLC13A2

  • solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 (SLC13A2)
  • deleted in malignant brain tumors 1 (DMBT1)
  • mucin (LOC100508689)
  • solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 (Slc13a2)
  • INDY Protein
  • mNaDC-1 Protein
  • mucin Protein
  • NaCT Protein
  • NaDC-1 Protein
  • Nadc1 Protein
  • SDCT1 Protein

Bezeichner auf Proteinebene für SLC13A2

solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 , gall-bladder mucin , Na(+)-coupled citrate transporter , Na(+)/dicarboxylate cotransporter 1 , renal sodium/dicarboxylate cotransporter , solute carrier family 13 member 2 , solute carrier family 13, member 2 , sodium/dicarboxylate cotransporter , naDC-1 , sodium/dicarboxylate co-transporter , intestinal sodium/dicarboxylate cotransporter , sodium-dependent dicarboxylate transporter

GENE ID SPEZIES
454528 Pan troglodytes
491167 Canis lupus familiaris
404104 Bos taurus
100508689 Homo sapiens
9058 Homo sapiens
505069 Bos taurus
100009593 Oryctolagus cuniculus
20500 Mus musculus
65202 Rattus norvegicus
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