anti-Solute Carrier Family 10 (Sodium/bile Acid Cotransporter Family), Member 2 (SLC10A2) Antikörper

SLC10A2 encodes a sodium/bile acid cotransporter. Zusätzlich bieten wir Ihnen Solute Carrier Family 10 (Sodium/bile Acid Cotransporter Family), Member 2 Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
SLC10A2 29500 Q62633
SLC10A2 6555 Q12908
SLC10A2 20494 P70172
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Top anti-Solute Carrier Family 10 (Sodium/bile Acid Cotransporter Family), Member 2 Antikörper auf antikoerper-online.de

Showing 10 out of 69 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Hund Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
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Hund Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
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Human Kaninchen Unkonjugiert IF (p), IHC (p) Formalin-fixed and paraffin embedded mouse intestine labeled with Anti ASBT/SLC10A2 Polyclonal Antibody, Unconjugated (ABIN755143) at 1:200 followed by conjugation to the secondary antibody and DAB staining. Formalin-fixed and paraffin embedded mouse intestine labeled with Anti ASBT/SLC10A2 Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Anmelden zum Anzeigen 9 bis 12 Tage
315,94 €
Details
Human Ziege Unkonjugiert IHC (p), IHC, ELISA, WB Immunohistochemistry-Paraffin: SLC10A2 Antibody [NBP1-36987] - 3.8ug/ml Staining of Human Small Intestine. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. 0.1 mg Anmelden zum Anzeigen 2 bis 4 Tage
311,00 €
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Maus Ziege Unkonjugiert ELISA, WB Western Blot: SLC10A2 Antibody [NBP1-20974] - (0.5ug/ml) staining of Mouse Small Intestine lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Anmelden zum Anzeigen 2 bis 4 Tage
311,00 €
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Maus Ziege Unkonjugiert EIA, WB   0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
357,50 €
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Human Ziege Unkonjugiert EIA, IHC (p) <div class= 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
385,00 €
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Human Ziege Unkonjugiert IHC (p), ELISA Anti-SLC10A2 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1104306 concentration 27454 ug/ml. 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
501,70 €
Details
Maus Ziege Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 11 bis 14 Tage
722,86 €
Details
Maus Kaninchen Unkonjugiert WB Mouse Slc10a2 Antibody (N-term)  western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the Mouse Slc10a2 antibody detected the Mouse Slc10a2 protein (arrow). 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
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SLC10A2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Solute Carrier Family 10 (Sodium/bile Acid Cotransporter Family), Member 2 Antikörper

  1. Dog (Canine) Polyclonal SLC10A2 Primary Antibody für WB - ABIN610792 : Kaukonen, Lahtinen, Laine, Alitalo, Palotie: BMX tyrosine kinase gene is expressed in granulocytes and myeloid leukaemias. in British journal of haematology 1996 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal SLC10A2 Primary Antibody für IF (p), IHC (p) - ABIN755143 : Wu, He, Wang, Xue, Ning, Zou, Ye, Li, Wang, Pang: The antihypercholesterolemic effect of jatrorrhizine isolated from Rhizoma Coptidis. in Phytomedicine : international journal of phytotherapy and phytopharmacology 2014 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal SLC10A2 Primary Antibody für IHC (p), IHC - ABIN450070 : Annaba, Sarwar, Kumar, Saksena, Turner, Dudeja, Gill, Alrefai: Modulation of ileal bile acid transporter (ASBT) activity by depletion of plasma membrane cholesterol: association with lipid rafts. in American journal of physiology. Gastrointestinal and liver physiology 2008 (PubMed)

Weitere Antikörper gegen Solute Carrier Family 10 (Sodium/bile Acid Cotransporter Family), Member 2 Interaktionspartner

Human Solute Carrier Family 10 (Sodium/bile Acid Cotransporter Family), Member 2 (SLC10A2) Interaktionspartner

  1. Data (including data from studies in knockout/transgenic mice) suggest that SLC10A2 is a functional receptor for hepatitis D virus in hepatocytes.

  2. Results unravel novel roles for N-glycosylation of ASBT and suggest that high levels of glucose alter the composition of the glycan and may contribute to the increase in ASBT function in diabetes mellitus.

  3. The p.Ser267Phe NTCP (zeige SLC10A1 Antikörper) variant is significantly associated with resistance to chronic hepatitis B and a lower incidence of acute-on-chronic liver failure. Our results support that NTCP (zeige SLC10A1 Antikörper) is a cellular receptor for HBV in human infection

  4. Data indicate that the lipid flippase (ATP8B1 (zeige ATP8B1 Antikörper))-transmembrane protein 30A (CDC50A) heterodimer is essential for the apical localization of sodium-dependent bile acid transporter (SLC10A2/ASBT) in Caco-2 cells.

  5. It was conclude that regulation of ASBT expression by resveratrol (RSV) may have clinical relevance with regard to the observed cholesterol-lowering effects of RSV.

  6. Transmembrane domain II of the human bile acid transporter SLC10A2 coordinates sodium translocation.

  7. ASBT evolved from the earliest vertebrates by gaining affinity for modern bile salts while retaining affinity for older bile salts

  8. This study provided novel evidence for the alterations in the activity of ASBT by enteropathogenic Escherichia coli infection.

  9. Presence of multiple functionally relevant variants in SLC10A2 that may influence bile acid homeostasis and physiology.

  10. The human ASBT promoter was activated transcriptionally by CDX1 (zeige CDX1 Antikörper) and CDX2 (zeige CDX2 Antikörper).

Mouse (Murine) Solute Carrier Family 10 (Sodium/bile Acid Cotransporter Family), Member 2 (SLC10A2) Interaktionspartner

  1. data support the concept that under physiological conditions microbiota stimulate Gata4 (zeige GATA4 Antikörper), which suppresses Asbt expression

  2. In Asbt-deficient mice, the lack of bile acid uptake in the distal small intestine, which we recently documented using novel in vivo imaging results in more than 10-fold increased fecal bile acids

  3. ileal ASBT protein is degraded by a ubiquitin-dependent pathway in response to enterobacteria-associated bile acids

  4. Ileal Fibroblast Growth Factor-15 (FGF15) expression was significantly reduced in Asbt(-/-)apoE (zeige APOE Antikörper)(-/-) mice and was inversely correlated with expression of hepatic cholesterol 7-hydroxylase (Cyp7a1 (zeige CYP7A1 Antikörper)).

  5. The functional importance of proline and uncharged polar residues in the highly conserved region of mouse Slc10a2 was determined.

  6. Enterobacteria-mediated bile acid biotransformation modulates intestinal bile acid transport via downregulation of SLC10A2 expression.

  7. These data confirm that bile acids and upregulation of ASBT play a crucial role in NEC pathogenesis and suggest that inhibition of ASBT could be utilized as a therapeutic modality against this disease.

  8. Slc10a2 is essential for efficient intestinal absorption of bile acids

  9. ASBT-mediated bile salt uptake in the distal ileum might also modulate intestinal fluid secretion

  10. The C51A and C106A mutants of Slc10a2 showed significantly reduced TCA uptake, while no apparent difference in TCA uptake was observed for the Slc10a1 (zeige SLC10A1 Antikörper)-C44A (zeige LYPD3 Antikörper) mutant.

Solute Carrier Family 10 (Sodium/bile Acid Cotransporter Family), Member 2 (SLC10A2) Antigen-Profil

Protein Überblick

This gene encodes a sodium/bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism, so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM)\; muatations in this gene may also be associated with other diseases of the liver and intestines, such as familial hypertriglyceridemia (FHTG).

Genbezeichner und Symbole assoziert mit SLC10A2

  • solute carrier family 10 (sodium/bile acid cotransporter family), member 2 (SLC10A2) Antikörper
  • solute carrier family 10 (sodium/bile acid cotransporter family), member 2 (slc10a2) Antikörper
  • solute carrier family 10 (sodium/bile acid cotransporter), member 2 (Slc10a2) Antikörper
  • solute carrier family 10 (sodium/bile acid cotransporter), member 2 (SLC10A2) Antikörper
  • solute carrier family 10, member 2 (Slc10a2) Antikörper
  • ASBT Antikörper
  • IBAT Antikörper
  • ISBAT Antikörper
  • ISBT Antikörper
  • NTCP2 Antikörper
  • PBAM Antikörper
  • zgc:63998 Antikörper

Bezeichner auf Proteinebene für SLC10A2

solute carrier family 10 (sodium/bile acid cotransporter family), member 2 , ileal sodium/bile acid cotransporter , ASBT , IBAT , ISBT , Na(+)-dependent ileal bile acid transporter , apical sodium-dependent bile acid transporter , ileal Na(+)/bile acid cotransporter , ileal sodium-dependent bile acid transporter , sodium/taurocholate cotransporting polypeptide, ileal , solute carrier family 10 member 2 , sodium/taurocholate-cotransporting polypeptide, ileal , solute carrier family 10, member 2 , ileal apical sodium-dependent bile acid transporter

GENE ID SPEZIES
428018 Gallus gallus
467318 Pan troglodytes
525823 Bos taurus
702376 Macaca mulatta
393329 Danio rerio
100171962 Pongo abelii
100009550 Oryctolagus cuniculus
29500 Rattus norvegicus
6555 Homo sapiens
20494 Mus musculus
Ausgewählte Anbieter für anti-Solute Carrier Family 10 (Sodium/bile Acid Cotransporter Family), Member 2 (SLC10A2) Antikörper
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