anti-Sodium Channel, Nonvoltage-Gated 1 alpha (SCNN1A) Antikörper

Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. Zusätzlich bieten wir Ihnen SCNN1A Kits (11) und SCNN1A Proteine (7) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
SCNN1A 6337 P37088
SCNN1A 20276 Q61180
SCNN1A 25122 P37089
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Showing 10 out of 143 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert FACS, IF, IHC (p), WB Western blot analysis of SCNN1A Antibody (Center) (ABIN652752) in WiDr cell line lysates (35 µg/lane). SCNN1A (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human lung carcinoma reacted with SCNN1A Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p) Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000; TMB staining; Read the data in MicroplateReader by 450 Formalin-fixed and paraffin embedded rat kidney labeled with Anti-Alpha-ENaC Polyclonal Antibody, Unconjugated (ABIN682243) at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Anmelden zum Anzeigen 9 bis 12 Tage
315,94 €
Details
Human Kaninchen Unkonjugiert FACS, ICC, IF, WB Western Blot: epithelial Sodium Channel alpha Antibody [ABIN2614667] - Analysis of 25 ug of Daudi (lane 1) and mouse brain (lane 2) cell lysates onto an SDS polyacrylamide gel. 0.1 mg Anmelden zum Anzeigen 2 bis 4 Tage
341,00 €
Details
Maus Kaninchen Unkonjugiert ICC, IF, IHC, WB ENaC alpha, rat kidney tissue. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
423,84 €
Details
Hamster Kaninchen Unkonjugiert ICC, IF, IP, IHC, WB ENaC beta, rat kidney tissue. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
423,84 €
Details
Human Kaninchen Unkonjugiert EIA, WB   0.4 mL Anmelden zum Anzeigen 8 bis 11 Tage
357,50 €
Details
Maus Kaninchen HRP ICC, IF, IHC, WB Western blot analysis of Rat kidney tissue lysates showing detection of ENaC protein using Rabbit Anti-ENaC Polyclonal Antibody . Primary Antibody: Rabbit Anti-ENaC Polyclonal Antibody  at 1:1000. Western blot analysis of Mouse kidney tissue lysates showing detection of ENaC protein using Rabbit Anti-ENaC Polyclonal Antibody . Primary Antibody: Rabbit Anti-ENaC Polyclonal Antibody  at 1:1000. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
465,74 €
Details
Maus Kaninchen FITC ICC, IF, IHC, WB Western blot analysis of Rat kidney tissue lysates showing detection of ENaC protein using Rabbit Anti-ENaC Polyclonal Antibody . Primary Antibody: Rabbit Anti-ENaC Polyclonal Antibody  at 1:1000. Western blot analysis of Mouse kidney tissue lysates showing detection of ENaC protein using Rabbit Anti-ENaC Polyclonal Antibody . Primary Antibody: Rabbit Anti-ENaC Polyclonal Antibody  at 1:1000. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
470,53 €
Details
Maus Kaninchen Alkaline Phosphatase (AP) ICC, IF, IHC, WB Western blot analysis of Rat kidney tissue lysates showing detection of ENaC protein using Rabbit Anti-ENaC Polyclonal Antibody . Primary Antibody: Rabbit Anti-ENaC Polyclonal Antibody  at 1:1000. Western blot analysis of Mouse kidney tissue lysates showing detection of ENaC protein using Rabbit Anti-ENaC Polyclonal Antibody . Primary Antibody: Rabbit Anti-ENaC Polyclonal Antibody  at 1:1000. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
472,92 €
Details
Maus Kaninchen Biotin ICC, IF, IHC, WB Western blot analysis of Rat kidney tissue lysates showing detection of ENaC protein using Rabbit Anti-ENaC Polyclonal Antibody . Primary Antibody: Rabbit Anti-ENaC Polyclonal Antibody  at 1:1000. Western blot analysis of Mouse kidney tissue lysates showing detection of ENaC protein using Rabbit Anti-ENaC Polyclonal Antibody . Primary Antibody: Rabbit Anti-ENaC Polyclonal Antibody  at 1:1000. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
475,32 €
Details

SCNN1A Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-SCNN1A Antikörper

  1. Mouse (Murine) Polyclonal SCNN1A Primary Antibody für ICC, IF - ABIN863202 : Jia, Liu, Sun, Kakizoe, Guan, Zhang, Zhou, Yang: mPGES-1-derived PGE2 mediates dehydration natriuresis. in American journal of physiology. Renal physiology 2013 (PubMed)
    Zeige alle 22 Referenzen für 863202

  2. Hamster Polyclonal SCNN1A Primary Antibody für ICC, IF - ABIN863203 : Gu: Effect of [Cl(-)]i on ENaC activity from mouse cortical collecting duct cells. in Journal of cellular physiology 2008 (PubMed)
    Zeige alle 22 Referenzen für 863203

  3. Mouse (Murine) Polyclonal SCNN1A Primary Antibody für ICC, IF - ABIN2486343 : Elias, Rafii, Rahman, Otulakowski, Cutz, OBrodovich: The role of alpha-, beta-, and gamma-ENaC subunits in distal lung epithelial fluid absorption induced by pulmonary edema fluid. in American journal of physiology. Lung cellular and molecular physiology 2007 (PubMed)
    Zeige alle 6 Referenzen für 2486343

  4. Mouse (Murine) Polyclonal SCNN1A Primary Antibody für ICC, IF - ABIN2486344 : Kakizoe, Kitamura, Ko, Wakida, Maekawa, Miyoshi, Shiraishi, Adachi, Zhang, Masilamani, Tomita: Aberrant ENaC activation in Dahl salt-sensitive rats. in Journal of hypertension 2009 (PubMed)
    Zeige alle 6 Referenzen für 2486344

  5. Mouse (Murine) Polyclonal SCNN1A Primary Antibody für ICC, IF - ABIN2486341 : Bruns, Hu, Ahn, Sheng, Hughey, Kleyman: Multiple epithelial Na+ channel domains participate in subunit assembly. in American journal of physiology. Renal physiology 2003 (PubMed)
    Zeige alle 6 Referenzen für 2486341

  6. Mouse (Murine) Polyclonal SCNN1A Primary Antibody für ICC, IF - ABIN2486345 : Mauro, Guitard, Behne, Oda, Crumrine, Komuves, Rassner, Elias, Hummler: The ENaC channel is required for normal epidermal differentiation. in The Journal of investigative dermatology 2002 (PubMed)
    Zeige alle 6 Referenzen für 2486345

  7. Human Polyclonal SCNN1A Primary Antibody für FACS, ICC - ABIN261466 : Williams, Chamarthi, Goodarzi, Pojoga, Sun, Garza, Raby, Adler, Hopkins, Brown, Jeunemaitre, Ferri, Fang, Leonor, Cui, Guo, Taylor, Ida Chen, Xiang, Raffel, Buchanan, Rotter, Williams, Shi: Lysine-specific demethylase 1: an epigenetic regulator of salt-sensitive hypertension. in American journal of hypertension 2012 (PubMed)
    Zeige alle 2 Referenzen für 261466

  8. Human Polyclonal SCNN1A Primary Antibody für IF (p), IHC (p) - ABIN682243 : Yamamoto, Hotta, Maeda, Kataoka, Maeda, Hamakawa, Sasaki, Yasui, Asai, Kimura: Mineralocorticoid receptor stimulation induces urinary storage dysfunction via upregulation of epithelial sodium channel expression in the rat urinary bladder epithelium. in Journal of pharmacological sciences 2016 (PubMed)

  9. Human Polyclonal SCNN1A Primary Antibody für FACS, IF - ABIN652752 : Azad, Rauh, Vermeulen, Jaspers, Korbmacher, Boissier, Bassinet, Fichou, des Georges, Stanke, De Boeck, Dupont, Balascáková, Hjelte, Lebecque: Mutations in the amiloride-sensitive epithelial sodium channel in patients with cystic fibrosis-like disease. in Human mutation 2009 (PubMed)

Weitere Antikörper gegen SCNN1A Interaktionspartner

Rabbit Sodium Channel, Nonvoltage-Gated 1 alpha (SCNN1A) Interaktionspartner

Human Sodium Channel, Nonvoltage-Gated 1 alpha (SCNN1A) Interaktionspartner

  1. The derlin-1 (zeige DERL1 Antikörper) pathway therefore may represent a significant early checkpoint in the recognition and degradation of ENaC in mammalian cells.

  2. Data show that the expression of aquaporin (AQP) 1 (zeige AQP1 Antikörper), AQP3 (zeige AQP3 Antikörper), AQP5 (zeige AQP5 Antikörper), epithelial Na+ channel (ENaC) and sodium potassium ATPase (zeige DNAH8 Antikörper) (Na-K-ATPase (zeige ATP1A1 Antikörper)) are altered in patients with acute respiratory failure (ARF (zeige CDKN2A Antikörper)) due to diffuse alveolar damage (DAD), and the cause of DAD does not seem to influence the level of impairment of these channels.

  3. The data indicate that the Lhs1 chaperone selectively recognizes an immature form of alphaENaC, one which has failed to correctly assemble with the other channel subunits via its transmembrane domain.

  4. LEFTY2 (zeige LEFTY2 Antikörper) regulates the expression and activity of ENaC in endometrial epithelial cells via SGK1 (zeige SGK1 Antikörper).

  5. Carriage of the p.W493R-SCNN1A polymorphism has been identified as a risk factor for bronchiectasis, but it is not invariably associated with the phenotype of a hyperactive ENaC channel in the lung.

  6. although subgroup analysis showed alpha-ENaC T663A polymorphism was associated with essential hypertension in North American individuals, these meta-analysis results did not confirm such association overall; conclude that Alpha-ENaC T663A polymorphism might not be a risk factor for essential hypertension

  7. Four nonsynonymous amino acid variants in SCNN1A in nonwhite Cystic fibrosis (zeige S100A8 Antikörper) patients with non-diagnostic CFTR (zeige CFTR Antikörper) genotypes was identified.

  8. The rs4149570 and rs7956915 polymorphisms of SCNN1A might play important roles in the susceptibility to respiratory distress syndrome, particularly in term infants.

  9. These results indicate that ENaC functions as a sensor for external Cd2 (zeige CD2 Antikörper)+.

  10. The transcriptional expression of alpha, beta, and gamma subunits of ENaC was elevated in nasal polyp compared to nasal mucosa

Xenopus laevis Sodium Channel, Nonvoltage-Gated 1 alpha (SCNN1A) Interaktionspartner

Mouse (Murine) Sodium Channel, Nonvoltage-Gated 1 alpha (SCNN1A) Interaktionspartner

  1. The derlin-1 (zeige DERL1 Antikörper) pathway therefore may represent a significant early checkpoint in the recognition and degradation of ENaC in mammalian cells.

  2. ENaC activity is regulated by calpain-2 (zeige CAPN2 Antikörper) proteolysis of MARCKS (zeige MARCKS Antikörper).

  3. nonselective cation channels ( channels consist of at least one alpha-ENaC and one or more acid-sensing ion channel (zeige ACCN2 Antikörper) 1a (ASIC1a (zeige ACCN2 Antikörper)) proteins.

  4. ENaC and ROMK (zeige KCNJ1 Antikörper) channel activity in kidney tubules are inhibited in TgWnk4(pseudoaldosteronism type II) mice. Wnk4 (zeige WNK4 Antikörper)(PHAII)-induced inhibition of ENaC and ROMK (zeige KCNJ1 Antikörper) may contribute to the suppression of K(+) secretion in the tubules.

  5. Exosomal GAPDH (zeige GAPDH Antikörper) from Proximal Tubule Cells Regulate ENaC Activity

  6. depletion of Kir4.1 (zeige KCNJ10 Antikörper) stimulates the expression of ENaCbeta (zeige SCNN1B Antikörper) and -gamma subunits in the cortical collecting duct

  7. LEFTY2 (zeige LEFTY2 Antikörper) regulates the expression and activity of ENaC in endometrial epithelial cells via SGK1 (zeige SGK1 Antikörper).

  8. reducing ENaC expression in the connecting tubule induces clear pseudohypoaldosteronism type 1 symptoms during high dietary potassium loading

  9. The findings demonstrated a substantial role of mitochondrial dysfunction in mediating the downregulation of NKCC2 (zeige SLC12A1 Antikörper) and ENaCalpha in obstructive kidney disease, possibly via iNOS (zeige NOS2 Antikörper)-derived nitric oxide and BNP (zeige BNC2 Antikörper).

  10. PCSK9 (zeige PCSK9 Antikörper)(-/-) mice display normal sodium balance and blood pressure regulation despite an increase of cleaved alphaENaC under basal condition

Guinea Pig Sodium Channel, Nonvoltage-Gated 1 alpha (SCNN1A) Interaktionspartner

  1. Different subunits of ENaC expressed in various cell regions of the cochlea and endolymphatic sac (zeige ADCY10 Antikörper) in distinct patterns may form the functional sodium channel to regulate the endolymph and maintain homeostasis in inner ear.

SCNN1A Antigen-Profil

Protein Überblick

Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the alpha subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Genbezeichner und Symbole assoziert mit SCNN1A

  • sodium channel, non-voltage-gated 1 alpha subunit (SCNN1A) Antikörper
  • sodium channel, nonvoltage-gated 1 alpha (SCNN1A) Antikörper
  • sodium channel, nonvoltage-gated 1 alpha (LOC100222046) Antikörper
  • epithelial sodium channel, alpha subunit (ALPHA-ENAC) Antikörper
  • sodium channel, non-voltage-gated 1 alpha subunit (scnn1a) Antikörper
  • sodium channel, nonvoltage-gated 1, delta (SCNN1D) Antikörper
  • sodium channel, nonvoltage-gated 1 alpha (Scnn1a) Antikörper
  • alphaxENaC Antikörper
  • besc2 Antikörper
  • ENAC Antikörper
  • enaca Antikörper
  • ENaCalpha Antikörper
  • mENaC Antikörper
  • SCNEA Antikörper
  • Scnn1 Antikörper
  • SCNN1A Antikörper

Bezeichner auf Proteinebene für SCNN1A

alpha-subunit renal epithelial sodium channel , amiloride-sensitive sodium channel subunit alpha , sodium channel, nonvoltage-gated 1 alpha , alpha ENaC , epithelial sodium channel alpha subunit , epithelium sodium channel alpha subunit , sodium channel, nonvoltage-gated 1, alpha , amiloride-sensitive sodium channel alpha subunit , SCNEA , alpha-NaCH , epithelial Na(+) channel subunit alpha , epithelial sodium channel ENaC alpha subunit , nonvoltage-gated sodium channel 1 subunit alpha , alpha ENaC-2 , alpha-ENaC , amiloride-sensitive epithelial sodium channel alpha subunit , amiloride-sensitive sodium channel subunit alpha 2 , nasal epithelial sodium channel alpha subunit , alpha cENaC 431 , amiloride-sensitve epithelial sodium channel alpha subunit , sodium channel, nonvoltage-gated 1, delta , ENaC alpha , amiloride-sensitive epithelial sodium channel , sodium channel, nonvoltage-gated, type I, alpha polypeptide , sodium channel, nonvoltage-gated, type I, alpha

GENE ID SPEZIES
396608 Sus scrofa
403650 Canis lupus familiaris
443488 Ovis aries
451776 Pan troglodytes
100222046 Taeniopygia guttata
100484947 Ailuropoda melanoleuca
100014763 Monodelphis domestica
100009488 Oryctolagus cuniculus
6337 Homo sapiens
282348 Bos taurus
396050 Gallus gallus
397811 Xenopus laevis
428184 Gallus gallus
20276 Mus musculus
25122 Rattus norvegicus
100135613 Cavia porcellus
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