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Sodium Channel, Nonvoltage-Gated 1, beta Proteine (SCNN1B)

Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. Zusätzlich bieten wir Ihnen SCNN1B Antikörper (163) und SCNN1B Kits (4) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
SCNN1B 6338 P51168
SCNN1B 20277 Q9WU38
Ratte SCNN1B SCNN1B 24767 P37090
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Showing 5 out of 7 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 46 bis 51 Tage
5.743,80 €
Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 46 bis 51 Tage
4.032,65 €
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HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
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Hefe Hund His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.035,88 €
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Hefe Schaf His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.430,48 €
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SCNN1B Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
, ,
Mouse (Murine)
,

Weitere Proteine zu Sodium Channel, Nonvoltage-Gated 1, beta (SCNN1B) Interaktionspartnern

Human Sodium Channel, Nonvoltage-Gated 1, beta (SCNN1B) Interaktionspartner

  1. hENaC incorporating the Liddle-mutated beta-subunit lacks one or more PKC phosphorylation sites, thereby significantly reducing the inhibitory effect of PKC on Na(+) channel activity, whereas hENaC incorporating Liddle-mutated gamma-subunits remains as susceptible to PKC as wild-type hENaC.

  2. deltabetagamma-ENaC (zeige SCNN1A Proteine) is inhibited by CFTR (zeige CFTR Proteine) but activated by cyclic AMP (zeige APRT Proteine).

  3. Results identify SCNN1B as a tumor-suppressive function that triggers UPR in gastric cancer cells, with implications for its potential clinical applications as a survival biomarker in gastric cancer patients.

  4. These results indicated a significant association between EH and SCNN1B methylation, which was affected by age, gender and antihypertensive therapy.

  5. Three nonsynonymous amino acid variants in SCNN1B in nonwhite Cystic fibrosis (zeige S100A8 Proteine) patients with non-diagnostic CFTR (zeige CFTR Proteine) genotypes was

  6. These results do not suggest an important role for the T594M variant of the ENaC (zeige SCNN1A Proteine) gene contributing to either the development or severity of hypertension in subjects of Indo (zeige IDO1 Proteine)-Aryan ancestry.

  7. The transcriptional expression of alpha, beta, and gamma subunits of ENaC (zeige SCNN1A Proteine) was elevated in nasal polyp compared to nasal mucosa

  8. causative mutation for Liddle's syndrome (LS) in this patient was identified to be a novel frameshift mutation. DNA sequencing resulted in exon 13 of SCNN1B gene: SCNN1B NM_000336.2:c.1 724_1730dupGGCCCAC [p.Pro5 75Argfs*17].

  9. analysis of a novel frameshift mutation in the betaENaC gene in an isolated case of Liddle syndrome

  10. Suggest that SCNN1B gene has important roles in blood pressure regulation in the Han Chinese population.

Mouse (Murine) Sodium Channel, Nonvoltage-Gated 1, beta (SCNN1B) Interaktionspartner

  1. Nedd4-2 (zeige NEDD4L Proteine)-mediated ubiquitination of beta-ENaC leading to endocytosis and degradation of apical Na(+) channels is a key feature of hypoxia-induced inhibition of transepithelial alveolar Na(+) transport.

  2. Data indicate that insulin receptor (InsR (zeige INSR Proteine)) is important for epithelial sodium channel (ENaC (zeige SCNN1A Proteine)) activity.

  3. Our findings are consistent with the role of betaENaC as a vascular smooth muscle cell mechanosensor and function of evolutionarily related nematode degenerin (zeige ACCN1 Proteine) proteins.

  4. These data suggest that adenylyl cyclase VI mediates vasopressin (zeige AVP Proteine)-stimulated ENaC (zeige SCNN1A Proteine) activity in the kidney.

  5. Cys (zeige DNAJC5 Proteine) substitutions at sites in the wrist domains of the beta and gamma subunits alter the Na+ self-inhibition response.

  6. ENaC (zeige SCNN1A Proteine) is not a passive passenger in regulated epithelial vesicle trafficking, but plays a role in establishing and maintaining the pool of vesicles that respond to cAMP stimulation.

  7. These findings demonstrate that myogenic constriction in afferent arterioles is dependent on normal expression of betaENaC

  8. loss of beta-ENaC associated with early signs of renal injury and increased mean arterial pressure

  9. generation of transgenic mice with airway-specific overexpression of the epithelial Na(+) channel (ENaC (zeige SCNN1A Proteine)) is an alternative approach to mimic cystic fibrosis (zeige S100A8 Proteine) ion transport pathophysiology in the lung

  10. Airway surface liquid volume regulation determines different airway phenotypes in liddle compared with betaENaC-overexpressing mice.

SCNN1B Protein Überblick

Protein Überblick

Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the beta subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), and Liddle syndrome.

Genbezeichner und Symbole assoziert mit SCNN1B

  • sodium channel, non-voltage-gated 1, beta subunit (SCNN1B)
  • sodium channel, non-voltage-gated 1, beta subunit (scnn1b)
  • sodium channel, nonvoltage-gated 1, beta (SCNN1B)
  • sodium channel, nonvoltage-gated 1 beta (Scnn1b)
  • sodium channel, nonvoltage-gated 1, beta (Scnn1b)
  • BESC1 Protein
  • BETA-ENAC Protein
  • ENaCb Protein
  • ENaCbeta Protein
  • RNENACB Protein
  • SCNEB Protein
  • SCNN1B Protein

Bezeichner auf Proteinebene für SCNN1B

sodium channel, nonvoltage-gated 1, beta , sodium channel, nonvoltage-gated 1, beta (Liddle syndrome) , amiloride-sensitive sodium channel subunit beta , amiloride-sensitive sodium channel subunit beta 1 , beta-ENaC , beta-NaCH , epithelial Na(+) channel subunit beta , epithelial sodium channel beta-2 subunit , epithelial sodium channel beta-3 subunit , nasal epithelial sodium channel beta subunit , nonvoltage-gated sodium channel 1 subunit beta , Amiloride-sensitive sodium channel subunit beta , epithelial amiloride-sensitive sodium channel beta subunit , SCNEB , epithelial sodium channel ENaC beta subunit , epithelial sodium channel, beta subunit , amiloride sensitive epithelial sodium ion channel beta subunit , epithelium sodium channel beta subunit , ENaC beta , amiloride sensitive sodium channel beta1 subunit , sodium channel, nonvoltage-gated, type I, beta

GENE ID SPEZIES
100069008 Equus caballus
453984 Pan troglodytes
700093 Macaca mulatta
779891 Xenopus (Silurana) tropicalis
100476005 Ailuropoda melanoleuca
100590266 Nomascus leucogenys
6338 Homo sapiens
489972 Canis lupus familiaris
100009564 Oryctolagus cuniculus
100627971 Sus scrofa
100170325 Ovis aries
20277 Mus musculus
100270805 Cavia porcellus
24767 Rattus norvegicus
533355 Bos taurus
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