Snail Homolog 2 (Drosophila) (SNAI2) ELISA Kits

SNAI2 encodes a member of the Snail family of C2H2-type zinc finger transcription factors.

list all ELISA KIts Gen GeneID UniProt
Anti-Human SNAI2 SNAI2 6591 O43623
Anti-Ratte SNAI2 SNAI2 25554 O08954
Anti-Maus SNAI2 SNAI2 20583 P97469
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Weitere ELISA Kits für Snail Homolog 2 (Drosophila) Interaktionspartner

Xenopus laevis Snail Homolog 2 (Drosophila) (SNAI2) Interaktionspartner

  1. Interaction with Snail1 (zeige SNAI1 ELISA Kits)/2, and Twist function more generally, is regulated by GSK-3-beta (zeige GSK3b ELISA Kits)-mediated phosphorylation of conserved sites in the WR domain.

  2. The Slug controls epithelial-mesenchymal transitions during both embryonic development and tumor metastasis.

  3. These results identify Snail2 as a key regulator of the signals involved in mesodermal induction of neural crest.

  4. A dinucleotide TGTGT/ACACA (zeige ACACA ELISA Kits) repeat in the cis (zeige CISH ELISA Kits)-element of Snail2 (previously 'Slug') gene contributes to repression of neural crest cell differentiation and migration by all-trans retinoic acid in Xenopus laevis embryos.

Human Snail Homolog 2 (Drosophila) (SNAI2) Interaktionspartner

  1. UCA1 overexpression promoted cell epithelial-mesenchymal transition (EMT) in hepatocellular carcinoma via effectively sponging to miR-203 and thereby activating the expression of transcription factor Snail2.

  2. High SLUG expression is associated with lung metastasis in ovarian cancer.

  3. overexpression of miR (zeige MLXIP ELISA Kits)-218 in H1299 increased chemosensitivity of cells to cisplatin treatment through suppression of Slug and ZEB2 (zeige ZEB2 ELISA Kits). These findings highlight an important role of miR (zeige MLXIP ELISA Kits)-218 in the regulation of EMT (zeige ITK ELISA Kits)-related traits and metastasis of lung cancer in part by modulation of Slug/ZEB2 (zeige ZEB2 ELISA Kits) signaling, and provide a potential therapeutic strategy by targeting miR (zeige MLXIP ELISA Kits)-218 in lung cancer.

  4. regulation of cancer stem cell via SLUG-SOX9 (zeige SOX9 ELISA Kits) regulatory axis

  5. our current findings highlight how Slug functions as an important transcriptional repressor that finely regulates the SCF (zeige KITLG ELISA Kits)/c-Kit (zeige KIT ELISA Kits) signaling pathway.

  6. we infer that Slug enhances MMP1 (zeige MMP1 ELISA Kits) transcription via directly binding to the promoter region in breast cancer cells, which is a previously unrecognized mechanism in the development of multi-drug resistance.

  7. The findings demonstrate that miR (zeige MLXIP ELISA Kits)-203a plays an essential role in keratinocyte proliferation and differentiation caused by extracellular calcium by targeting the SNAI2 and DeltaNp63 genes.

  8. Slug expression was higher in cyclosporine A (CsA)-induced gingival overgrowth specimens than in clinical healthy gingiva. In addition, knockdown of Slug significantly suppressed CsA-induced cell proliferation in human gingival fibroblasts (HGFs). Upregulation of Slug in HGFs stimulated by CsA may play an important role in the pathogenesis of CsA-induced gingival overgrowth.

  9. gastrointestinal stromal tumour (GIST) patients with high tumour SLUG expression have unfavourable recurrence-free survival. SLUG may mediate pro-survival signalling in GISTs.

  10. Slug emerges as a key transcription factor driving smooth muscle cell towards a proliferative phenotype.

Mouse (Murine) Snail Homolog 2 (Drosophila) (SNAI2) Interaktionspartner

  1. our current findings highlight how Slug functions as an important transcriptional repressor that finely regulates the SCF (zeige KITLG ELISA Kits)/c-Kit (zeige KIT ELISA Kits) signaling pathway.

  2. Slug emerges as a key transcription factor driving smooth muscle cell towards a proliferative phenotype.

  3. both Snail (zeige SNAI1 ELISA Kits) and Slug are able to form binary complexes with either YAP (zeige YAP1 ELISA Kits) or TAZ (zeige TAZ ELISA Kits) that, together, control YAP (zeige YAP1 ELISA Kits)/TAZ (zeige TAZ ELISA Kits) transcriptional activity and function throughout mouse development.

  4. results demonstrate that skeletal stem/stromal cell mobilize Snail (zeige SNAI1 ELISA Kits)/Slug-YAP (zeige YAP1 ELISA Kits)/TAZ (zeige TAZ ELISA Kits) complexes to control stem cell function

  5. The data presented here demonstrate that Snai2 and Snai3 (zeige SNAI3 ELISA Kits) transcriptionally regulate the cellular fitness and functionality of not only CD4 (zeige CD4 ELISA Kits)(+) regulatory T cells but effector CD8(alpha+) and CD4 (zeige CD4 ELISA Kits)(+) conventional T cells as well.

  6. TGFbeta3 increases IRF6 (zeige IRF6 ELISA Kits) expression and subsequently regulates SNAI2 expression; IRF6 (zeige IRF6 ELISA Kits) appears to regulate epithelial mesenchymal transition during palatal fusion via SNAI2.

  7. Our work demonstrates the participation of SNAI2 in the pathogenesis of luminal breast cancer, and reveals an unexpected connection between the processes of postlactational involution and breast tumorigenesis in Snai2-null mutant mice.

  8. SNAI2-driven BIM (zeige BCL2L11 ELISA Kits)-induced apoptosis may temper metastasis by governing the survival of disseminating breast tumor cells.

  9. Data indicate that deletion of snail (zeige SNAI1 ELISA Kits) family transcription factors Snai2 and Snai3 (zeige SNAI3 ELISA Kits) in bone marrow-derived cells is sufficient to induce autoantibody generation.

  10. Loss of Snail2 favors skin tumor progression by promoting the recruitment of myeloid progenitors.

Zebrafish Snail Homolog 2 (Drosophila) (SNAI2) Interaktionspartner

  1. Snail (zeige SNAI1 ELISA Kits) genes lie in regions of extensive paralogy, revealing their common origin through segmental or chromosomal duplication

Snail Homolog 2 (Drosophila) (SNAI2) Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects.

Genbezeichner und Symbole assoziert mit SNAI2

  • snail homolog 2 (Drosophila) (SNAI2) Antikörper
  • snail family zinc finger 2 (snai2) Antikörper
  • snail family zinc finger 2 (snai2-b) Antikörper
  • snail family zinc finger 2 (SNAI2) Antikörper
  • snail family zinc finger 2 (Snai2) Antikörper
  • snail family zinc finger 2 (snai2-a) Antikörper
  • snail homolog 2 (Drosophila) (Snai2) Antikörper
  • snail homolog 2 (Drosophila) (snai2) Antikörper
  • cb147 Antikörper
  • cb355 Antikörper
  • id:ibd5003 Antikörper
  • sb:cb355 Antikörper
  • sb:cb569 Antikörper
  • Slug Antikörper
  • Slugh Antikörper
  • SLUGH1 Antikörper
  • snai2 Antikörper
  • SNAIL2 Antikörper
  • WS2D Antikörper
  • wu:fb83e12 Antikörper
  • wu:fd19g11 Antikörper
  • xSlu Antikörper
  • xslug Antikörper
  • xsna Antikörper
  • XSnail2 Antikörper
  • zgc:92564 Antikörper

Bezeichner auf Proteinebene für SNAI2

snail 2 , Protein snail-like protein 2 , zinc finger protein SNAI2 , snail homolog 2 , zinc finger transcription factor slug , zinc finger transcription factor slug beta , neural crest transcription factor SLUG , protein snail homolog 2 , slug (chicken homolog), zinc finger protein , Slug, chicken homolog , neural crest transcription factor Slug , protein slug-alpha , slug alpha , snail protein homolog Slug , xSlu , slug , zinc finger transcription factor snail 2 , zinc-finger transcription factor SLUG , slug, chicken homolog

GENE ID SPEZIES
464169 Pan troglodytes
708962 Macaca mulatta
395065 Xenopus (Silurana) tropicalis
100023459 Monodelphis domestica
398235 Xenopus laevis
6591 Homo sapiens
25554 Rattus norvegicus
379440 Xenopus laevis
432368 Gallus gallus
486940 Canis lupus familiaris
641345 Sus scrofa
520631 Bos taurus
20583 Mus musculus
494038 Danio rerio
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