Small Conductance Calcium-Activated Potassium Channel Protein 3 (KCNN3) ELISA Kits

Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Zusätzlich bieten wir Ihnen KCNN3 Antikörper (19) und KCNN3 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
Anti-Ratte KCNN3 KCNN3 54263 P70605
Anti-Human KCNN3 KCNN3 3782 Q9UGI6
Anti-Maus KCNN3 KCNN3 140493  
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Weitere ELISA Kits für KCNN3 Interaktionspartner

Human Small Conductance Calcium-Activated Potassium Channel Protein 3 (KCNN3) Interaktionspartner

  1. Analyses of tissue microarray from colorectal cancer patients showed higher SigmaR1 (zeige SIGMAR1 ELISA Kits) expression levels in cancer samples and a correlation with tumor grade. Moreover, the exploration of a cohort of 4937 breast cancer patients indicated that high expression of SigmaR1 (zeige SIGMAR1 ELISA Kits) and Orai1 (zeige ORAI1 ELISA Kits) channels was significantly correlated to a lower overall survival

  2. Edelfosine is able to effectively inhibit migration and invasion of UC cells in vitro and in vivo in an SK3-dependent way, pointing towards a possible role for Edelfosine as an antiinvasive drug to effectively inhibit UC cell invasion and metastasis.

  3. KCNN3 gene encodes small conductance calcium-activated potassium (SK) channel 3

  4. Patients with Dilated Cardiomyopathy and Sustained Monomorphic Ventricular Tachycardia Show Up-Regulation of KCNN3 and KCNJ2 (zeige KCNJ2 ELISA Kits) Genes and CACNG8 (zeige CACNG8 ELISA Kits)-Linked Left Ventricular Dysfunction

  5. Decreased SK3 expression in ganglionic bowel may explain the basis of persistent bowel symptoms in some patients following a properly performed pull-through operation for Hirschsprung's disease.

  6. KCNN3 single-nucleotide polymorphism rs13376333 significantly increases the risk of Atrial Fibrillation.

  7. SK3 channel and mitochondrial ROS (zeige ROS1 ELISA Kits) mediate NADPH oxidase (zeige NOX1 ELISA Kits)-independent NETosis induced by calcium influx.

  8. Reduced SK3 expression attenuates endometrial cell migration and is associated with unsuccessful pregnancy outcomes.

  9. Intermediate conductance Ca2 (zeige CA2 ELISA Kits)+-activated K+ channels modulate human placental trophoblast syncytialization.

  10. Differentiated dopaminergic neurons expressed low levels of SK2 channels and high levels of SK1 and SK3 channels.

Pig (Porcine) Small Conductance Calcium-Activated Potassium Channel Protein 3 (KCNN3) Interaktionspartner

  1. SK channels (KCNN1 (zeige KCNN1 ELISA Kits) and KCNN3) provide a mechanism for sensing changes in intracellular Ca(2 (zeige CA2 ELISA Kits)+) near the apical membrane, evoking hyperpolarization necessary for increasing the driving force for anion efflux following P2Y (zeige P2RY1 ELISA Kits) receptor activation [KCNN1 (zeige KCNN1 ELISA Kits)].

Cow (Bovine) Small Conductance Calcium-Activated Potassium Channel Protein 3 (KCNN3) Interaktionspartner

  1. Small conductance family member KCNN3 channel subtypes are activated in response to basolateral ATP challenge, essential in driving chloride secretion and thus fluid formation in the oviduct.

Mouse (Murine) Small Conductance Calcium-Activated Potassium Channel Protein 3 (KCNN3) Interaktionspartner

  1. Dynamic coupling between TRPV4 (zeige TRPV4 ELISA Kits) and Ca(2 (zeige CA2 ELISA Kits)+)-activated SK1 (zeige SPHK1 ELISA Kits)/3 and IK1 (zeige KCNN4 ELISA Kits) K(+) channels plays a critical role in regulating the K(+)-secretory BK channel KCNMA1 (zeige KCNMA1 ELISA Kits) in kidney collecting duct cells.

  2. SK3 signaling microdomain modulates endothelial Ca(2+) dynamics, vascular tone, and blood pressure. SK3 knockout mice are hypertensive.

  3. The data of this study implicated the family of KCNN genes in alcohol, nicotine, and drug addiction, and identify KCNN3 as a mediator of voluntary and excessive alcohol consumption

  4. ovariectomy leads to a reduction in endothelial SK3 channel activity thereby reducing the SK3 contribution to endothelium-dependent hyperpolarization vasorelaxation.

  5. Atrial SK2 and SK3 are significantly down-regulated from accelerated turnover in diabetic mice, resulting in action potential prolongation and arrhythmias.

  6. Pulmonary hypertension in wild type mice and animals with genetic deficit in KCa2.3 and KCa3.1 (zeige KCNN4 ELISA Kits) channels

  7. SK3 channel modulates placental vascular development and fetal health by altering VEGF signaling.

  8. SK3 is functionally expressed in the distal nephron and collecting ducts where induction of TRPV4 (zeige TRPV4 ELISA Kits)-mediated Ca2 (zeige CA2 ELISA Kits)+ influx activates the channel.

  9. Reduced SK3 expression attenuates endometrial cell migration and is associated with unsuccessful pregnancy outcomes.

  10. SK3 channel contributes importantly towards atrial action potential repolarization.

KCNN3 Antigen-Profil

Beschreibung des Gens

Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. This gene belongs to the KCNN family of potassium channels. It encodes an integral membrane protein that forms a voltage-independent calcium-activated channel, which is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. This gene contains two CAG repeat regions in the coding sequence. It was thought that expansion of one or both of these repeats could lead to an increased susceptibility to schizophrenia or bipolar disorder, but studies indicate that this is probably not the case. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit KCNN3

  • potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 (Kcnn3) Antikörper
  • potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 (KCNN3) Antikörper
  • hSK3 Antikörper
  • KCa2.3 Antikörper
  • SK3 Antikörper
  • SKCA3 Antikörper

Bezeichner auf Proteinebene für KCNN3

SKCa 3 , SKCa3 , small conductance calcium-activated potassium channel protein 3 , small-conductance Ca2+-activated K+ channel 3 , SK3 , calcium activated potassium channel SK3 , small conductance calcium-activated potassium channel 3

GENE ID SPEZIES
54263 Rattus norvegicus
3782 Homo sapiens
490441 Canis lupus familiaris
397045 Sus scrofa
534180 Bos taurus
140493 Mus musculus
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