anti-Small Conductance Calcium-Activated Potassium Channel Protein 3 (KCNN3) Antikörper

Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Zusätzlich bieten wir Ihnen KCNN3 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
KCNN3 54263 P70605
KCNN3 3782 Q9UGI6
KCNN3 140493  
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Top anti-KCNN3 Antikörper auf antikoerper-online.de

Showing 10 out of 19 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB WB Suggested Anti-KCNN3 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Daudi cell lysate 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Maus Unkonjugiert ELISA, WB KCNN3 polyclonal antibody (A01), Lot # 050921JC01 Western Blot analysis of KCNN3 expression in Y-79 . Western Blot detection against Immunogen (38.21 KDa) . 50 μL Anmelden zum Anzeigen 7 bis 8 Tage
241,60 €
Details
Hund Kaninchen Unkonjugiert ELISA, WB 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
459,65 €
Details
Fledermaus Kaninchen Unkonjugiert IHC (p), WB Human Prostate (formalin-fixed, paraffin-embedded) stained with KCNN3 antibody ABIN214788 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Skin (formalin-fixed, paraffin-embedded) stained with KCNN3 antibody ABIN214788 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
801,43 €
Details
Human Kaninchen Unkonjugiert IHC Immunohistochemistry (IHC) analysis of paraffin-embedded Rat Brain Tissue using KCNN3(SK3) Rabbit Polyclonal Antibody diluted at 1:200. 100 μL Anmelden zum Anzeigen 13 Days
154,33 €
Details
Human Kaninchen Unkonjugiert IHC, WB Immunohistochemical analysis of KCNN3 staining in human gastric cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated w Western blot analysis of KCNN3 expression in Raji (A), mouse heart (B), mouse livere (C), rat brain (D) whole cell lysates. 200 μL Anmelden zum Anzeigen 11 bis 13 Tage
464,29 €
Details
Human Kaninchen Unkonjugiert IHC, IHC (p) Immunohistochemistry: KCNN3 Antibody [NBP2-14144] - Staining of human urinary bladder shows moderate cytoplasmic and membranous positivity in urothelial cells. 0.1 mL Anmelden zum Anzeigen 5 bis 8 Tage
335,00 €
Details
Human Kaninchen Unkonjugiert ICC, IF Immunocytochemistry/Immunofluorescence: KCNN3 Antibody  - Staining of human cell line PC-3 shows localization to nucleoplasm. 100 μL Anmelden zum Anzeigen 5 bis 8 Tage
335,00 €
Details
Human Kaninchen Unkonjugiert WB KCNN3 antibody used at 2.5 ug/ml to detect target protein. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
379,93 €
Details
Human Kaninchen Unkonjugiert IHC, WB   100 μL Anmelden zum Anzeigen 10 bis 12 Tage
433,02 €
Details

KCNN3 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
Rat (Rattus) ,


Human , , ,
,

Mouse (Murine)


Am meisten referenzierte anti-KCNN3 Antikörper

  1. Human Polyclonal KCNN3 Primary Antibody für IHC, WB - ABIN350425 : Chandy, Fantino, Wittekindt, Kalman, Tong, Ho, Gutman, Crocq, Ganguli, Nimgaonkar, Morris-Rosendahl, Gargus: Isolation of a novel potassium channel gene hSKCa3 containing a polymorphic CAG repeat: a candidate for schizophrenia and bipolar disorder? in Molecular psychiatry 1998 (PubMed)
    Zeige alle 5 Referenzen für 350425

  2. Cow (Bovine) Polyclonal KCNN3 Primary Antibody für IHC, WB - ABIN2776146 : Kolski-Andreaco, Tomita, Shakkottai, Gutman, Cahalan, Gargus, Chandy: SK3-1C, a dominant-negative suppressor of SKCa and IKCa channels. in The Journal of biological chemistry 2004 (PubMed)

  3. Human Polyclonal KCNN3 Primary Antibody für ELISA, WB - ABIN561588 : Coyle, ODonnell, Puri: Altered distribution of small-conductance calcium-activated potassium channel SK3 in Hirschsprung's disease. in Journal of pediatric surgery 2015 (PubMed)

Weitere Antikörper gegen KCNN3 Interaktionspartner

Human Small Conductance Calcium-Activated Potassium Channel Protein 3 (KCNN3) Interaktionspartner

  1. Analyses of tissue microarray from colorectal cancer patients showed higher SigmaR1 (zeige SIGMAR1 Antikörper) expression levels in cancer samples and a correlation with tumor grade. Moreover, the exploration of a cohort of 4937 breast cancer patients indicated that high expression of SigmaR1 (zeige SIGMAR1 Antikörper) and Orai1 (zeige ORAI1 Antikörper) channels was significantly correlated to a lower overall survival

  2. Edelfosine is able to effectively inhibit migration and invasion of UC cells in vitro and in vivo in an SK3-dependent way, pointing towards a possible role for Edelfosine as an antiinvasive drug to effectively inhibit UC cell invasion and metastasis.

  3. KCNN3 gene encodes small conductance calcium-activated potassium (SK) channel 3

  4. Patients with Dilated Cardiomyopathy and Sustained Monomorphic Ventricular Tachycardia Show Up-Regulation of KCNN3 and KCNJ2 (zeige KCNJ2 Antikörper) Genes and CACNG8 (zeige CACNG8 Antikörper)-Linked Left Ventricular Dysfunction

  5. Decreased SK3 expression in ganglionic bowel may explain the basis of persistent bowel symptoms in some patients following a properly performed pull-through operation for Hirschsprung's disease.

  6. KCNN3 single-nucleotide polymorphism rs13376333 significantly increases the risk of Atrial Fibrillation.

  7. SK3 channel and mitochondrial ROS (zeige ROS1 Antikörper) mediate NADPH oxidase (zeige NOX1 Antikörper)-independent NETosis induced by calcium influx.

  8. Reduced SK3 expression attenuates endometrial cell migration and is associated with unsuccessful pregnancy outcomes.

  9. Intermediate conductance Ca2 (zeige CA2 Antikörper)+-activated K+ channels modulate human placental trophoblast syncytialization.

  10. Differentiated dopaminergic neurons expressed low levels of SK2 channels and high levels of SK1 and SK3 channels.

Pig (Porcine) Small Conductance Calcium-Activated Potassium Channel Protein 3 (KCNN3) Interaktionspartner

  1. SK channels (KCNN1 (zeige KCNN1 Antikörper) and KCNN3) provide a mechanism for sensing changes in intracellular Ca(2 (zeige CA2 Antikörper)+) near the apical membrane, evoking hyperpolarization necessary for increasing the driving force for anion efflux following P2Y (zeige P2RY1 Antikörper) receptor activation [KCNN1 (zeige KCNN1 Antikörper)].

Cow (Bovine) Small Conductance Calcium-Activated Potassium Channel Protein 3 (KCNN3) Interaktionspartner

  1. Small conductance family member KCNN3 channel subtypes are activated in response to basolateral ATP challenge, essential in driving chloride secretion and thus fluid formation in the oviduct.

Mouse (Murine) Small Conductance Calcium-Activated Potassium Channel Protein 3 (KCNN3) Interaktionspartner

  1. Dynamic coupling between TRPV4 (zeige TRPV4 Antikörper) and Ca(2 (zeige CA2 Antikörper)+)-activated SK1 (zeige SPHK1 Antikörper)/3 and IK1 (zeige KCNN4 Antikörper) K(+) channels plays a critical role in regulating the K(+)-secretory BK channel KCNMA1 (zeige KCNMA1 Antikörper) in kidney collecting duct cells.

  2. SK3 signaling microdomain modulates endothelial Ca(2+) dynamics, vascular tone, and blood pressure. SK3 knockout mice are hypertensive.

  3. The data of this study implicated the family of KCNN genes in alcohol, nicotine, and drug addiction, and identify KCNN3 as a mediator of voluntary and excessive alcohol consumption

  4. ovariectomy leads to a reduction in endothelial SK3 channel activity thereby reducing the SK3 contribution to endothelium-dependent hyperpolarization vasorelaxation.

  5. Atrial SK2 and SK3 are significantly down-regulated from accelerated turnover in diabetic mice, resulting in action potential prolongation and arrhythmias.

  6. Pulmonary hypertension in wild type mice and animals with genetic deficit in KCa2.3 and KCa3.1 (zeige KCNN4 Antikörper) channels

  7. SK3 channel modulates placental vascular development and fetal health by altering VEGF signaling.

  8. SK3 is functionally expressed in the distal nephron and collecting ducts where induction of TRPV4 (zeige TRPV4 Antikörper)-mediated Ca2 (zeige CA2 Antikörper)+ influx activates the channel.

  9. Reduced SK3 expression attenuates endometrial cell migration and is associated with unsuccessful pregnancy outcomes.

  10. SK3 channel contributes importantly towards atrial action potential repolarization.

KCNN3 Antigen-Profil

Protein Überblick

Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. This gene belongs to the KCNN family of potassium channels. It encodes an integral membrane protein that forms a voltage-independent calcium-activated channel, which is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. This gene contains two CAG repeat regions in the coding sequence. It was thought that expansion of one or both of these repeats could lead to an increased susceptibility to schizophrenia or bipolar disorder, but studies indicate that this is probably not the case. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit KCNN3

  • potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 (Kcnn3) Antikörper
  • potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 (KCNN3) Antikörper
  • hSK3 Antikörper
  • KCa2.3 Antikörper
  • SK3 Antikörper
  • SKCA3 Antikörper

Bezeichner auf Proteinebene für KCNN3

SKCa 3 , SKCa3 , small conductance calcium-activated potassium channel protein 3 , small-conductance Ca2+-activated K+ channel 3 , SK3 , calcium activated potassium channel SK3 , small conductance calcium-activated potassium channel 3

GENE ID SPEZIES
54263 Rattus norvegicus
3782 Homo sapiens
490441 Canis lupus familiaris
397045 Sus scrofa
534180 Bos taurus
140493 Mus musculus
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