Slingshot Protein Phosphatase 2 (SSH2) ELISA Kits

The ADF (actin-depolymerizing factor)/cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics.

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SSH2 85464 Q76I76
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Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 0.113 ng/mL 0.312-20 ng/mL 96 Tests Anmelden zum Anzeigen 13 bis 16 Tage
875,63 €
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Weitere ELISA Kits für Slingshot Protein Phosphatase 2 Interaktionspartner

Human Slingshot Protein Phosphatase 2 (SSH2) Interaktionspartner

  1. Novel signaling pathway consisting of chemoattractant GPCR/Galphai protein, PLC, PKCbeta and PKDs that regulates SSH2/cofilin activity, F-actin polymerization and directional assembly of actin cytoskeleton in neutrophil chemotaxis was identified.

  2. data indicate that: (a) apoptotic cell death in FLCN (zeige FLCN ELISA Kits)-null cells can be triggered by SSH2 knockdown through cell cycle arrest; (b) SSH2 represents a potential therapeutic target for the development of agents for the treatment of BHD (zeige FLCN ELISA Kits) syndrome related tumors

  3. Expression of phosphatase-dead versions of SSH proteins, SSH1 (zeige SSH1 ELISA Kits), SSH2 & SSH3 (zeige SSH3 ELISA Kits) results in phosphorylation/inactivation of cofilin (zeige CFL1 ELISA Kits), changes in cytoskeleton organization, loss of cell polarity, and assembly of aberrant arrays of laminin-332 in keratinocytes.

Slingshot Protein Phosphatase 2 (SSH2) Antigen-Profil

Beschreibung des Gens

The ADF (actin-depolymerizing factor)/cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1\; MIM 601329). The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo (Niwa et al., 2002

Genbezeichner und Symbole assoziert mit SSH2

  • slingshot protein phosphatase 2 (SSH2) Antikörper
  • SSH-2 Antikörper
  • SSH-2L Antikörper

Bezeichner auf Proteinebene für SSH2

SSH-like protein 2 , protein phosphatase Slingshot homolog 2

GENE ID SPEZIES
85464 Homo sapiens
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