anti-Sirtuin 5 (SIRT5) Antikörper

SIRT5 encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Zusätzlich bieten wir Ihnen Sirtuin 5 Proteine (18) und Sirtuin 5 Kits (16) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
SIRT5 23408 Q9NXA8
SIRT5 68346 Q8K2C6
SIRT5 306840 Q68FX9
Direkt bei antikoerper-online bestellen
  • +49 (0)241 95 163 153
  • +49 (0)241 95 163 155
  • Online bestellen
  • orders@antikoerper-online.de

Top anti-Sirtuin 5 Antikörper auf antikoerper-online.de

Showing 10 out of 177 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB <b>WB Suggested Anti-SIRT5 Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB <b>WB Suggested Anti-SIRT5 Antibody Titration: </b>1.0-2.0ug/ml<br><b>Positive Control: </b>Jurkat cell lysate 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
288,68 €
Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-SIRT5 <br /> Antibody Titration: 5.0 µg/mL ELISA Titer: 1:.2500 <br /> Positive Control: Human heart 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
288,68 €
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Human Kaninchen Unkonjugiert IHC (fro), IF (p), IHC (p), WB Mouse splenocytes probed with Rabbit Anti-SIRT5 Polyclonal Antibody, Unconjugated . Image provided by One World Lab validation program. PC3 cells probed with SIRT5 Polyclonal Antibody  at 1:50 for 60 minutes at room temperature followed by Goat Anti-Rabbit IgG (H+L) Alexa Fluor 488 Conjugated secondary antibody. 100 μL Anmelden zum Anzeigen 9 bis 12 Tage
315,94 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma Western blot analysis of anti-SIRT5 Pab (ABIN390180) in Jurkat cell line lysate (35 µg/lane). SIRT5(arrow) was detected using the purified polyclonal antibody. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of SIRT5 in A) human, B) mouse and C) rat intestine cell lysate using ABIN252349 at 2 ug/ml. 0.1 mg Anmelden zum Anzeigen 2 bis 4 Tage
291,00 €
Details
Human Maus Unkonjugiert FACS, IF, IHC, WB Anti-SIRT5 mouse monoclonal antibody (ABIN2454822) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SIRT5 (RC200189). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SIRT5 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-SIRT5. 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
366,67 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
517,00 €
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 11 bis 14 Tage
583,17 €
Details

SIRT5 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Human , , , ,
, , ,
,
, , , , , , , , , , , , , , , ,
Mouse (Murine) ,
,

, , , , , , , , , , , , ,
Rat (Rattus) ,
,
,
, , , , , , , , , , , , ,

Am meisten referenzierte anti-Sirtuin 5 Antikörper

  1. Human Polyclonal SIRT5 Primary Antibody für IHC (p), WB - ABIN390180 : Wang, Yi, Li, Cai, He, Ni, Zhou, Cheng, Jin, Fan, Qiu: Down-regulation of sirtuin 3 is associated with poor prognosis in hepatocellular carcinoma after resection. in BMC cancer 2014 (PubMed)

  2. Human Polyclonal SIRT5 Primary Antibody für IHC, IHC (p) - ABIN4353920 : Lv, Liu, Cheng, Yu, Xiong, Hu, Tang, Zeng, Sang: SUN2 exerts tumor suppressor functions by suppressing the Warburg effect in lung cancer. in Scientific reports 2015 (PubMed)

  3. Human Polyclonal SIRT5 Primary Antibody für IHC (fro), IF (p) - ABIN1387080 : Takumida, Takumida, Anniko: Localization of sirtuins in the mouse inner ear. in Acta oto-laryngologica 2014 (PubMed)

  4. Human Polyclonal SIRT5 Primary Antibody für WB - ABIN252349 : Alhazzazi, Kamarajan, Joo, Huang, Verdin, DSilva, Kapila: Sirtuin-3 (SIRT3), a novel potential therapeutic target for oral cancer. in Cancer 2011 (PubMed)

  5. Cow (Bovine) Polyclonal SIRT5 Primary Antibody für WB - ABIN2778619 : Mahlknecht, Ho, Letzel, Voelter-Mahlknecht: Assignment of the NAD-dependent deacetylase sirtuin 5 gene (SIRT5) to human chromosome band 6p23 by in situ hybridization. in Cytogenetic and genome research 2006 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen Sirtuin 5 Interaktionspartner

Human Sirtuin 5 (SIRT5) Interaktionspartner

  1. Our study uncovers a SIRT5-dependent mechanism that regulates cellular NADPH (zeige NQO1 Antikörper) homeostasis and redox potential by promoting IDH2 (zeige IDH2 Antikörper) desuccinylation and G6PD (zeige G6PD Antikörper) deglutarylation.

  2. Results demonstrated presence of endogenous SIRT5 in mitochondria of cultured SH-EP cells, identified down-regulation of cellular oxidative stress by SIRT5 as one of the possible mechanisms mediating the anti-apoptotic effect of SIRT5 in SH-EP cells.

  3. Data (including data from studies using knockout mice) suggest that SIRT5 is targeted to protein complexes on the inner mitochondrial membrane via affinity for cardiolipin to promote respiratory chain function, particularly Complex I and Complex II; SIRT5 expression is observed in inner mitochondrial membrane of periportal hepatocytes.

  4. a side chain-to-side chain cyclic pentapeptide harboring a central N(epsilon)-carboxyethyl-thiocarbamoyl-lysine residue behaved as a strong and selective (versus human SIRT1 (zeige SIRT1 Antikörper)/2/3/6) inhibitor against human SIRT5-catalyzed deacylation reaction.

  5. Data indicate that compared to non-neoplastic endometria (NNE (zeige ENO1 Antikörper)), endometrial cancer (EC) showed SIRT7 (zeige SIRT7 Antikörper) mRNA overexpression, whereas SIRT1 (zeige SIRT1 Antikörper), SIRT2 (zeige SIRT2 Antikörper), SIRT4 (zeige SIRT4 Antikörper) and SIRT5 were underexpressed, and no significant differences were observed for SIRT3 (zeige SIRT3 Antikörper) and SIRT6 (zeige SIRT6 Antikörper).

  6. Use of a pan (zeige SUPT6H Antikörper)-sirtuin (zeige SIRT1 Antikörper) inhibitor and shRNA-mediated protein knockdown led us to uncover a role for the NAD(+)-dependent family of sirtuins, and in particular for SIRT2 (zeige SIRT2 Antikörper) and SIRT5, in the regulation of the necroptotic cell death program

  7. mutual cooperation between Y102 and R105 residues in promoting the desuccinylation versus deacetylation reaction in SIRT5.

  8. Data showed that SIRT5 was involved in protein post-translational modifications through its potent demalonylase, desuccinylase, and deglutarylase activities. Also, the protein was found in the mitochondrial, cytoplasmic, and nuclear compartments. [review]

  9. Results show that mitochondrial sirtuins SIRT3 (zeige SIRT3 Antikörper), SIRT4 (zeige SIRT4 Antikörper), and SIRT5 can promote increased mitochondrial respiration and cellular metabolism and respond to excess glucose by inducing a coordinated increase of glycolysis and respiration.

  10. Results suggest a role for SIRT5 in influencing oocyte quality and in vitro fertilization outcomes.

Cow (Bovine) Sirtuin 5 (SIRT5) Interaktionspartner

  1. Association analysis of individual SIRT5 SNPs and haplotype combinations reveal that the 4 loci are significantly associated with some body measurement and ultrasound traits in Qinchuan cattle.

Mouse (Murine) Sirtuin 5 (SIRT5) Interaktionspartner

  1. Deletion of Sirt5 in starved mouse embryonic fibroblasts increased levels of mitochondrial dynamics leading to mitochondrial accumulation of the pro-fission Drp1 (zeige CRMP1 Antikörper) and to mitochondrial fragmentation.

  2. Our study uncovers a SIRT5-dependent mechanism that regulates cellular NADPH (zeige FDXR Antikörper) homeostasis and redox potential by promoting IDH2 (zeige IDH2 Antikörper) desuccinylation and G6PD (zeige G6PD Antikörper) deglutarylation.

  3. Data (including data from studies using knockout mice) suggest that SIRT5 is targeted to protein complexes on the inner mitochondrial membrane via affinity for cardiolipin to promote respiratory chain function, particularly Complex I and Complex II; SIRT5 expression is observed in inner mitochondrial membrane of periportal hepatocytes.

  4. Data show that peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1alpha (zeige PPARGC1A Antikörper)) overexpression significantly increased the expression of sirtuin 3 (SIRT3 (zeige SIRT3 Antikörper)) and sirtuin 5 (SIRT5).

  5. In the cochlea, the expression of SIRT1 (zeige SIRT1 Antikörper), 3, and 5 (both mRNA and protein) was decreased in the old mice

  6. These findings establish that regulating heart metabolism and function is a major physiological function of lysine succinylation and SIRT5.

  7. Myocardial ischemic reperfusion injury in Sirt5-/- heart is restored to wild-type levels by pretreatment with dimethyl malonate, a competitive inhibitor of succinate dehydrogenase (SDH (zeige SDHA Antikörper)), implicating alteration in SDH (zeige SDS Antikörper) activity as causative of the injury.

  8. SIRT5 has a role in cellular metabolism with a multiple enzymatic activities

  9. SIRT3 (zeige SIRT3 Antikörper) and SIRT5 regulate the enzyme activity and cardiolipin binding of very long-chain acyl-CoA dehydrogenase (zeige ACADVL Antikörper)

  10. Pathway analysis identified glycolysis as the top SIRT5-regulated pathway. Importantly, glycolytic flux was diminished in primary hepatocytes from Sirt5(-/-) compared to WT mice.

Sirtuin 5 (SIRT5) Antigen-Profil

Protein Überblick

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined\; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class III of the sirtuin family. Alternative splicing of this gene results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit anti-Sirtuin 5 (SIRT5) Antikörper

  • sirtuin (silent mating type information regulation 2 homolog) 5 (S. cerevisiae) (SIRT5) Antikörper
  • sirtuin 5 (CC1G_00083) Antikörper
  • sirtuin 5 (sirt5) Antikörper
  • sirtuin 5 (SIRT5) Antikörper
  • sirtuin (silent mating type information regulation 2 homolog) 5 (S. cerevisiae) (sirt5) Antikörper
  • sirtuin 5 (Sirt5) Antikörper
  • 0610012J09Rik Antikörper
  • 1500032M05Rik Antikörper
  • AV001953 Antikörper
  • SIR2L5 Antikörper
  • SIRT5 Antikörper
  • sirt5-a Antikörper
  • zgc:92288 Antikörper

Bezeichner auf Proteinebene für anti-Sirtuin 5 (SIRT5) Antikörper

sirtuin (silent mating type information regulation 2 homolog) 5 (S. cerevisiae) , sirtuin 5 , NAD-dependent lysine demalonylase and desuccinylase sirtuin-5, mitochondrial , NAD-dependent protein deacylase sirtuin-5, mitochondrial , regulatory protein SIR2 homolog 5 , sirtuin (silent mating type information regulation 2 homolog) 5 , NAD-dependent deacetylase sirtuin-5 , SIR2-like protein 5 , nad-dependent deacetylase sirtuin-5 , silent mating type information regulation 2, S.cerevisiae, homolog 5 , sir2-like 5 , sirtuin type 5 , NAD-dependent lysine demalonylase and desuccinylase sirtuin-5A, mitochondrial , NAD-dependent protein deacylase sirtuin-5A, mitochondrial , regulatory protein SIR2 homolog 5-a , Regulatory protein SIR2 homolog 5

GENE ID SPEZIES
700855 Macaca mulatta
747069 Pan troglodytes
6013501 Coprinopsis cinerea okayama7130
100170199 Xenopus (Silurana) tropicalis
100173543 Pongo abelii
100528250 Ictalurus punctatus
436878 Danio rerio
23408 Homo sapiens
496346 Xenopus laevis
420834 Gallus gallus
478726 Canis lupus familiaris
100125966 Sus scrofa
507347 Bos taurus
68346 Mus musculus
306840 Rattus norvegicus
Ausgewählte Anbieter für anti-Sirtuin 5 (SIRT5) Antikörper
Haben Sie etwas anderes gesucht?