anti-Sialic Acid Binding Ig-Like Lectin 5 (SIGLEC5) Antikörper

SIGLEC5 encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. Zusätzlich bieten wir Ihnen SIGLEC5 Proteine (19) und SIGLEC5 Kits (6) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
SIGLEC5 8778 O15389
SIGLEC5 233186 Q920G3
SIGLEC5 292843  
Direkt bei antikoerper-online bestellen
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Online bestellen
  • orders@antikoerper-online.de

Top anti-SIGLEC5 Antikörper auf antikoerper-online.de

Showing 10 out of 167 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert EIA, WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Maus Unkonjugiert CyTOF, ELISA (Capture), FACS, Neut Cell Adhesion Mediated by Siglec-5 and Neutralization by Human Siglec-5/14 Antibody. Recombinant Human Siglec-5 Fc Chimera. The ND50 is typically 0.04-0.2 ug/mL. Detection of Siglec-5/14 in Human Monocytes by Flow Cytometry. Human blood derived monocytes were stained with Mouse Anti-Human Siglec-5/14 Monoclonal Antibody. 500 μg Anmelden zum Anzeigen 8 bis 9 Tage
$346.50
Details
Human Ziege Unkonjugiert CyTOF, FACS, IHC, Neut, WB Cell Adhesion Mediated by Siglec-5 and Neutralization by Human Siglec-5/14 Antibody. Recombinant Human Siglec-5 Fc Chimera. The ND50 is typically 0.5-2.0 ug/mL. Detection of Siglec-5/14 in Human Monocytes by Flow Cytometry. Human whole blood monocytes were stained with Human Siglec-5/14 Antigen Affinity-purified Polyclonal Antibody. 100 μg Anmelden zum Anzeigen 8 bis 9 Tage
$393.75
Details
Human Kaninchen Unkonjugiert EIA, WB Western blot analysis of CD170 / SIGLEC5 Antibody  in NCI-H460 cell line lysates (35ug/lane).This demonstrates the SIGLEC5 antibody detected the SIGLEC5 protein (arrow). 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of CD170 expression in L929 (A), mouse lung (B) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Maus Fluorescein FACS Detection of Siglec-5/Siglec-14 in Human Monocytes by Flow Cytometry. Human monocytes were stained with Mouse Anti-Human Siglec-5/Siglec-14 Fluorescein-conjugated Monoclonal Antibody. Detection of Siglec-5/Siglec-14 in Human Monocytes by Flow Cytometry. Human monocytes were stained with Mouse Anti-Human Siglec-5/Siglec-14 Fluorescein-conjugated Monoclonal Antibody. 100 Tests Anmelden zum Anzeigen 8 bis 9 Tage
$262.50
Details
Human Maus Allophycocyanin FACS Detection of Siglec-5/Siglec-14 in Human Monocytes by Flow Cytometry. Human monocytes were stained with Mouse Anti-Human Siglec-5/Siglec-14 APC-conjugated Monoclonal Antibody. 100 Tests Anmelden zum Anzeigen 8 bis 9 Tage
$357.00
Details
Human Ziege Biotin FACS, WB Detection of Siglec-5 and Siglec-14 in Human Monocytes and Granulocytes by Flow Cytometry. Human whole blood monocytes and granulocytes were stained with Human Siglec-5/14 Biotinylated Antigen Affinity-purified Polyclonal Antibody. Detection of Siglec-5 and Siglec-14 in Human Monocytes and Granulocytes by Flow Cytometry. Human whole blood monocytes and granulocytes were stained with Human Siglec-5/14 Biotinylated Antigen Affinity-purified Polyclonal Antibody. 50 μg Anmelden zum Anzeigen 8 bis 9 Tage
$399.00
Details
Human Kaninchen Unkonjugiert IHC (p), WB The anti-Siglec5 N-term Pab (ABIN388414) is used in Western blot to detect Siglec5 in mouse liver tissue lysate. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details

SIGLEC5 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Human , , , ,
, ,
,
, , , , , , , , , , , , , , , , , , ,
Mouse (Murine) , , ,
,
,
, , , , , , , , , , , , , , , ,
Rat (Rattus) ,


Am meisten referenzierte anti-SIGLEC5 Antikörper

  1. Human Monoclonal SIGLEC5 Primary Antibody für CyTOF, ELISA (Capture) - ABIN4899350 : Gunnarsson, Fornander, Påhlsson, Grenegård: Sialic acid residues play a pivotal role in alpha(1)-acid glycoprotein (AGP)-induced generation of reactive oxygen species in chemotactic peptide pre-activated neutrophil granulocytes. in Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2010 (PubMed)
    Show all 4 Pubmed References

  2. Human Monoclonal SIGLEC5 Primary Antibody für FACS - ABIN4895978 : Soto, Stein, Hurtado-Ziola, Hedrick, Varki: Relative over-reactivity of human versus chimpanzee lymphocytes: implications for the human diseases associated with immune activation. in Journal of immunology (Baltimore, Md. : 1950) 2010 (PubMed)
    Show all 3 Pubmed References

  3. Mouse (Murine) Monoclonal SIGLEC5 Primary Antibody für IHC (fro), FACS - ABIN2689902 : Angata, Hingorani, Varki, Varki: Cloning and characterization of a novel mouse Siglec, mSiglec-F: differential evolution of the mouse and human (CD33) Siglec-3-related gene clusters. in The Journal of biological chemistry 2001 (PubMed)
    Show all 2 Pubmed References

  4. Human Polyclonal SIGLEC5 Primary Antibody für FACS, WB - ABIN4899349 : Zou, Chastain, Moir, Ford, Trandem, Martinelli, Cicala, Crocker, Arthos, Sun: Siglecs facilitate HIV-1 infection of macrophages through adhesion with viral sialic acids. in PLoS ONE 2011 (PubMed)
    Show all 2 Pubmed References

  5. Human Polyclonal SIGLEC5 Primary Antibody für CyTOF, FACS - ABIN4899306 : Costelloe, Watson, Murphy, McQuillan, Loscher, Armstrong, Garlanda, Mantovani, ONeill, Mills, Lynch: IL-1F5 mediates anti-inflammatory activity in the brain through induction of IL-4 following interaction with SIGIRR/TIR8. in Journal of neurochemistry 2008 (PubMed)
    Show all 2 Pubmed References

  6. Human Monoclonal SIGLEC5 Primary Antibody für FACS - ABIN4895979 : Ali, Fong, Carlin, Busch, Linden, Angata, Areschoug, Parast, Varki, Murray, Nizet, Varki: Siglec-5 and Siglec-14 are polymorphic paired receptors that modulate neutrophil and amnion signaling responses to group B Streptococcus. in The Journal of experimental medicine 2014 (PubMed)

Weitere Antikörper gegen SIGLEC5 Interaktionspartner

Human Sialic Acid Binding Ig-Like Lectin 5 (SIGLEC5) Interaktionspartner

  1. An unbiased screen revealed Hsp70 (zeige HSP70 Antikörper) as a ligand for Siglec-5 and Siglec-14 (zeige SIGLEC14 Antikörper). Hsp70 (zeige HSP70 Antikörper) stimulation through Siglec-5 delivers an anti-inflammatory signal, while stimulation through Siglec-14 (zeige SIGLEC14 Antikörper) is pro-inflammatory.

  2. Data indicate that the Siglec-5/14 genotype influences neutrophil responses to group B Streptococcus.

  3. we found that secretory IgA is taken up by M cells via the Dectin-1 (zeige CLEC7A Antikörper) receptor, with the possible involvement of Siglec-5 acting as a co-receptor.

  4. These studies demonstrate the Siglec5 carbohydrate recognition domain alone is sufficient for binding sialylated carbohydrates and provide a foundation for further investigation of Siglec5 structure and function.

  5. Siglec-5 expression protects T cells from HIV-1- and apoptosis-induced cell death and contributes to the different outcomes of HIV-1 infection in humans and chimpanzees.

  6. Human Siglec-5 inhibitory receptor and immunoglobulin A (IgA) have separate binding sites in streptococcal beta protein.

  7. Siglec-5 expression correlates with lack of proliferation in a subset of human cells, and is upregulated by activation of chimpanzee but not human lymphocytes.

  8. expression of Siglec-5 on cells of the myelomonocytic lineage and alteration of its expression by inflammatory stimuli suggest a role for this protein in cell/cell interactions following microbial exposure.

  9. Siglec-5 can be classified as an inhibitory receptor with the potential to mediate SHP-1 and/or SHP-2-dependent signaling in the absence of tyrosine phosphorylation.

  10. Siglecs-5 did not interact with sulfate derivatives of LacNAc and sulfated (zeige SULF1 Antikörper) oligosaccharides containing sialic acid.

Mouse (Murine) Sialic Acid Binding Ig-Like Lectin 5 (SIGLEC5) Interaktionspartner

  1. The Siglec-E-deficient dendritic cells were defective for TRIF (zeige RNF138 Antikörper)-mediated IFN-beta (zeige IFNB1 Antikörper) production in response to E. coli infection.

  2. This study demonstrated that virulent parasite Leishmania donovani (AG83+Sias) establish a unique sialic acids-mediated binding and subsequent phagocytosis in the host cell through the selective exploitation of siglec-1 (zeige SIGLEC1 Antikörper).

  3. Immunohistochemical analysis of the Peyer's patches (PPs (zeige INPP5K Antikörper)) tissue sections shows that Siglec-F is expressed on the surface of the Intestinal microfold (M) cell membrane exposed to the intestinal lumen.

  4. new data relating to the structure and function of Siglec-E, the major CD33 (zeige CD33 Antikörper)-related Siglec expressed on mouse neutrophils, monocytes, macrophages, and dendritic cells.

  5. indicate that Siglec-9 (zeige SIGLEC9 Antikörper) affects several different signaling pathways in IL-4 (zeige IL4 Antikörper)-stimulated macrophages, which resulted in enhanced induction of Arg1 (zeige ARG1 Antikörper) in Siglec-9 (zeige SIGLEC9 Antikörper)-expressing RAW264 cells

  6. Competitive ELISA assays confirmed the involvement of sulfated (zeige SULF1 Antikörper) epitopes in the affinity between Siglec-E and cruzipain, probably modified by natural protein environment

  7. These data identify a previously unrecognized endogenous anti-inflammatory property of airway mucins by which their glycans can control lung eosinophilia through engagement of Siglec-F.

  8. Data indicate a role for neuraminidase 1 (Neu1 (zeige NEU1 Antikörper)) in regulating Siglec E protein-toll-like receptor 4 (TLR4 (zeige TLR4 Antikörper)) interaction and endotoxemia.

  9. Siglec-E-deficient macrophages showed a propensity toward a tumor-promoting M2 polarization, indicating a secondary role of CD33 (zeige CD33 Antikörper)-related Siglecs in limiting cancer-promoting inflammation and tumor growth.

  10. depending on the nature of the allergy model used, the negative regulatory role of siglec-F on eosinophilia may be overridden.

SIGLEC5 Antigen-Profil

Protein Überblick

This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion.

Genbezeichner und Symbole assoziert mit SIGLEC5

  • sialic acid binding Ig-like lectin 5 (SIGLEC5) Antikörper
  • sialic acid binding Ig-like lectin 5 (Siglec5) Antikörper
  • sialic acid binding Ig-like lectin E (Siglece) Antikörper
  • CD33L2 Antikörper
  • Cd170 Antikörper
  • mSiglec-E Antikörper
  • mSiglec-F Antikörper
  • OB-BP2 Antikörper
  • OBBP2 Antikörper
  • SIGLEC-5 Antikörper
  • Siglec5 Antikörper
  • Siglec9 Antikörper
  • Siglec12 Antikörper
  • Siglecf Antikörper
  • Siglecl1 Antikörper

Bezeichner auf Proteinebene für SIGLEC5

sialic acid binding Ig-like lectin 5 , CD33 antigen-like 2 , OB-binding protein 2 , obesity-binding protein 2 , sialic acid-binding Ig-like lectin 5 , sialic acid-binding immunoglobulin-like lectin 5 , sialic acid binding Ig-like lectin F , sialic acid-binding Ig-like lectin F , sialic acid-binding lectin Siglec-F , siglec-5 , siglec-F , MIS , SIGLEC-like 1 , myeloid inhibitory siglec , sialic acid-binding Ig-like lectin 12 , sialic acid-binding Ig-like lectin E , sialic acid-binding Ig-like lectin-like 1 , sialic acid-binding immunoglobulin-like lectin E , siglec-12 , siglec-E , siglec-L1

GENE ID SPEZIES
100597560 Nomascus leucogenys
8778 Homo sapiens
233186 Mus musculus
292843 Rattus norvegicus
83382 Mus musculus
Ausgewählte Anbieter für anti-SIGLEC5 (SIGLEC5) Antikörper
Haben Sie etwas anderes gesucht?