anti-Sestrin 2 (SESN2) Antikörper

SESN2 encodes a member of the sestrin family of PA26-related proteins. Zusätzlich bieten wir Ihnen Sestrin 2 Kits (17) und Sestrin 2 Proteine (7) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
SESN2 83667 P58004
SESN2 230784 P58043
SESN2 502988  
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Top anti-Sestrin 2 Antikörper auf antikoerper-online.de

Showing 10 out of 53 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-SESN2 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: MCF7 cell lysate 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
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Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
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Human Kaninchen Unkonjugiert FACS, WB Western blot analysis of Sestrin-2 Antibody (Center) (ABIN652222) in 293 cell line lysates (35 µg/lane). Sestrin-2 (arrow) was detected using the purified polyclonal antibody. Sestrin-2 Antibody (Center) (ABIN652222) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
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Human Kaninchen Unkonjugiert EIA, WB (LEFT) Western blot analysis of Sestrin-2 Antibody (Center) in 293 cell line lysates (35ug/lane). Sestrin-2 (arrow) was detected using the purified Pab. (RIGHT) Western blot analysis of SESN2 (arrow) using rabbit polyclonal Sestrin-2 Antibody (Center) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the SESN2 gene (Lane 2). 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
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Rind (Kuh) Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
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Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p) Immunocytochemistry/Immunofluorescence: SESN2 Antibody [NBP1-85029] - Immunofluorescent staining of human cell line A-431 shows positivity in cytoplasm. Immunohistochemistry-Paraffin: SESN2 Antibody [NBP1-85029] - Staining of human colon shows strong cytoplasmic positivity in glandular cells. 0.1 mL Anmelden zum Anzeigen 5 bis 8 Tage
335,00 €
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Human Maus Unkonjugiert IF, IHC (p), IP, ELISA, WB Immunoperoxidase of monoclonal antibody to SESN2 on formalin-fixed paraffin-embedded human ovary, clear cell carcinoma. [antibody concentration 3 ug/ml] SESN2 monoclonal antibody (M03), clone 3B8 Western Blot analysis of SESN2 expression in K-562 100 μg Anmelden zum Anzeigen 7 bis 8 Tage
369,60 €
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Human Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
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Human Kaninchen Unkonjugiert WB Western Blot: SESN2 Antibody [NBP2-20317] - A. 30 ug Raji whole cell lysate/extract B. 30 ug K562 whole cell lysate/extract10 % SDS-PAGE SESN2 antibody dilution: 1:1000. 0.1 mL Anmelden zum Anzeigen 3 bis 6 Tage
341,00 €
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Human Maus Unkonjugiert IF, WB Immunofluorescence of to SES2 on HeLa cell . SESN2 monoclonal antibody (M03), clone 3B8 Western Blot analysis of SESN2 expression in K-562. 0.1 mg Anmelden zum Anzeigen 12 bis 16 Tage
454,76 €
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SESN2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Sestrin 2 Antikörper

  1. Human Monoclonal Sestrin 2 Primary Antibody für IF, IHC (p) - ABIN566510 : Liu, Lee, Lee: Association of platelet-derived growth factor receptor ? accumulation with increased oxidative stress and cellular injury in sestrin 2 silenced human glioblastoma cells. in FEBS letters 2011 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal Sestrin 2 Primary Antibody für ICC, IF - ABIN4353033 : Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013 (PubMed)

Weitere Antikörper gegen Sestrin 2 Interaktionspartner

Human Sestrin 2 (SESN2) Interaktionspartner

  1. The data are the first to indicate that SESN2 might be a novel prognostic marker for hepatocellular carcinoma

  2. The up-regulation of SESN2 by mitochondrial dysfunction requires binding to ATF4 (zeige ATF4 Antikörper).

  3. Sesn2 has two subdomains. The N-terminal domain reduces alkylhydroperoxide radicals through its helix-turn-helix oxidoreductase (zeige TXNRD1 Antikörper) motif, and the C-terminal domain interacts with GATOR2 and subsequently inhibits mTORC1.

  4. SESN2-AMPK (zeige PRKAA1 Antikörper) signaling could exert a protective effect against glucose deprivation-induced cell death and that this effect is mediated by restoration of mitochondrial function.

  5. Sesn2 is a potential tumor suppressor in lung epithelial cells. The expression level of Sesn2 may serve as a prognostic marker for Chinese lung cancer patients in the clinic.

  6. The findings suggested that a decreased expression of sestrin 2 is associated with an unfavorable prognosis, which suggests that it is a novel and crucial predictor for colorectal cancer metastasis.

  7. an AMPK (zeige PRKAA1 Antikörper)-independent mechanism of mTORC1 inhibition by Sestrins mediated by their interaction with GATOR2, is reported.

  8. GAA (zeige GAA Antikörper) promotes FoxO3 (zeige FOXO3 Antikörper) nuclear translocation and binding to the SESN2 enhancer.

  9. Data indicate that inactivation of Sestrin 2 (Sesn2) or nuclear factor erythroid 2-related factor 2 (Nrf2 (zeige NFE2L2 Antikörper)) induced reactive oxygen species-mediated proteasomal inhibition and platelet-derived growth factor receptor beta (zeige PDGFRB Antikörper) (Pdgfrbeta) accumulation.

  10. Sesn2 is oncogenic in skin squamous cell carcinoma and melanoma.

Mouse (Murine) Sestrin 2 (SESN2) Interaktionspartner

  1. Decreased Sesn2 levels in aging lead to a blunted ischemic AMPK (zeige PRKAA1 Antikörper) activation, alterations in substrate metabolism, and an increased sensitivity to ischemic insults.

  2. p53 (zeige TP53 Antikörper)-dependent coordination with SESN2 regulates AMPK (zeige PRKAA1 Antikörper) and mTORC1 signaling and controls parturition timing

  3. Our findings further revealed that Sesn2-induced autophagy contributed to restore the impaired insulin (zeige INS Antikörper) signaling through the activation of AMPK (zeige PRKAA1 Antikörper) signal. Even in the presence of palmitate, Sesn2 up-regulation maintained insulin (zeige INS Antikörper) sensitivity and glucose metabolism via AMPK (zeige PRKAA1 Antikörper)-dependent autophagic activation.

  4. Oleanolic acid can attenuate hepatic ischemia reperfusion injury via HO-1 (zeige HMOX1 Antikörper)/Sesn2 signaling pathway.

  5. suggest that TLR-mediated Sesn2 induction is dependent on AP-1 (zeige JUN Antikörper), Nrf2 (zeige NFE2L2 Antikörper), and the inhibition of ubiquitin-mediated degradation of Sesn2 and might protect cells against endotoxin toxicity

  6. an AMPK (zeige PRKAA1 Antikörper)-independent mechanism of mTORC1 inhibition by Sestrins mediated by their interaction with GATOR2, is reported.

  7. Study found that Sestrins (1,2 and 3) can inhibit mTORC1 signaling in the absence of AMPK (zeige PRKAA1 Antikörper) or TSC2 (zeige TSC2 Antikörper). Surprisingly, when coexpressed with a GTP (zeige AK3 Antikörper)-bound constitutively active form of RagB (zeige RRAGB Antikörper) (RagBQ99L), Sestrins potentiate mTORC1 signaling in the absence of amino acids.

  8. Sestrin2 plays an important role in cardioprotection against I/R injury, serving as an LKB1 (zeige STK11 Antikörper)-AMPK (zeige PRKAA1 Antikörper) scaffold to initiate AMPK (zeige PRKAA1 Antikörper) activation during ischemic insults

  9. Data indicate that sestrin2 expression is upregulated by dopamine D2 receptor (zeige DRD2 Antikörper).

  10. this study identifies ULK1 as a new p62 Ser403 kinase and establishes Sestrin2 as a promoter of ULK1-mediated p62 phosphorylation.

Sestrin 2 (SESN2) Antigen-Profil

Protein Überblick

This gene encodes a member of the sestrin family of PA26-related proteins. The encoded protein may function in the regulation of cell growth and survival. This protein may be involved in cellular response to different stress conditions.

Genbezeichner und Symbole assoziert mit anti-Sestrin 2 (SESN2) Antikörper

  • sestrin 2 (sesn2) Antikörper
  • sestrin 2 (SESN2) Antikörper
  • sestrin 2 (LOC100353543) Antikörper
  • sestrin 2 (Sesn2) Antikörper
  • HI95 Antikörper
  • MGC81239 Antikörper
  • RGD1566319 Antikörper
  • Ses2 Antikörper
  • SESN2 Antikörper
  • SEST2 Antikörper
  • Sestrin-2 Antikörper

Bezeichner auf Proteinebene für anti-Sestrin 2 (SESN2) Antikörper

sestrin 2 , sestrin-2 , sestrin-2-like , hypoxia induced gene 95

GENE ID SPEZIES
414641 Xenopus laevis
469167 Pan troglodytes
487335 Canis lupus familiaris
558966 Danio rerio
716904 Macaca mulatta
733499 Xenopus (Silurana) tropicalis
100056552 Equus caballus
100172219 Pongo abelii
100353543 Oryctolagus cuniculus
100397149 Callithrix jacchus
100469808 Ailuropoda melanoleuca
100592235 Nomascus leucogenys
83667 Homo sapiens
230784 Mus musculus
502988 Rattus norvegicus
509863 Bos taurus
Ausgewählte Anbieter für anti-Sestrin 2 (SESN2) Antikörper
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