Septin 4 Proteine (SEPT4)

SEPT4 is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Zusätzlich bieten wir Ihnen Septin 4 Antikörper (64) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
Ratte SEPT4 SEPT4 287606  
SEPT4 5414 O43236
SEPT4 18952 P28661
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Showing 4 out of 6 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 56 Days
7.380,00 €
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Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 56 Days
7.380,00 €
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HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 16 Days
748,00 €
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HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
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SEPT4 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine)

Weitere Proteine zu Septin 4 (SEPT4) Interaktionspartnern

Human Septin 4 (SEPT4) Interaktionspartner

  1. The data suggest that Sept4_i1 induces hepatic stellate cell apoptosis by inhibiting Akt (zeige AKT1 Proteine) and Bcl-2 (zeige BCL2 Proteine) expression and up-regulating PPAR-gamma (zeige PPARG Proteine) expression.

  2. Bradeion/SEPT4 transcript levels are significantly increased in patients with transitional cell bladder cancer.We hypothesize that Bradeion is directly involved in bladder cancer pathogenesis with the highest expression at early cancer stages.

  3. Identification of a novel anti-apoptotic E3 ubiquitin ligase (zeige MUL1 Proteine) that ubiquitinates antagonists of inhibitor of apoptosis proteins SMAC (zeige DIABLO Proteine), HtrA2 (zeige HTRA2 Proteine), and ARTS.

  4. these data suggests a tumor suppressor role of SEPT4_i1 in HCC (zeige FAM126A Proteine) through regulating hepatocellular carcinoma cell apoptosis.

  5. SEPT4 is a Notch (zeige NOTCH1 Proteine) target gene.

  6. The expression of SEPT4 is significantly decreased in the ejaculated sperm of idiopathic asthenozoospermia patients.

  7. role of Bradeion in colorectal neoplasms

  8. Sept4 is involved in the formation of cytoplasmic inclusions as well as induction of cell death in alpha-synuclein-associated neurodegenerative disorders.

  9. Data suggest that ARTS induces apoptosis by antagonizing IAPs, including XIAP (zeige XIAP Proteine).

  10. SEPT8 (zeige SEPT8 Proteine) and SEPT4 are localized surrounding alpha-granules. Activation of platelets by agonists resulted in the translocation of SEPT4 and SEPT8 (zeige SEPT8 Proteine) to the platelet surface indicating a possible functional role of these proteins in platelet granular secretion

Mouse (Murine) Septin 4 (SEPT4) Interaktionspartner

  1. Adenovirus-Sept4 can attenuate the development of liver fibrosis induced by S. japonicum through apoptosis.

  2. The inhibition of the expression of the SEPT4 by praziquantel might be due to alleviation of the inflammatory response at the chronic and advanced stage of S. japonicum infection.

  3. The hypothetical pathogenicity by the chronic overload of SEPT4 alone, if any, is insufficient to trigger neurodegenerative process in the mouse brain.

  4. Sept4/ARTS(-/-) mice display marked improvement in wound healing and regeneration of hair follicles.

  5. Identification of a novel anti-apoptotic E3 ubiquitin ligase (zeige MUL1 Proteine) that ubiquitinates antagonists of inhibitor of apoptosis proteins SMAC (zeige DIABLO Proteine), HtrA2 (zeige HTRA2 Proteine), and ARTS.

  6. Report SEPT4/5/7 expression in mouse cochlea and roles in auditory function.

  7. Sept4 and alpha-SMA (zeige SMN1 Proteine) may interact together in hepatic stellate cells (HSCs). Sept4 seems to be involved in the formation of inflammatory granulomata and subsequent liver fibrosis by regulating HSCs activation.

  8. ARTS (Septin 4) promotes apoptosis mainly through binding and antagonizing XIAP (zeige XIAP Proteine).

  9. Loss of Sept4 is associated with myofibroblastic transformation of hepatic stellate cells and results in liver fibrosis.

  10. Findings suggest that Sept4-null mice develop malignancies due to increased resistance of their HSPCs to apoptosis.

Septin 4 (SEPT4) Protein Überblick

Protein Überblick

This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. One of the isoforms (known as ARTS) is distinct\; it is localized to the mitochondria, and has a role in apoptosis and cancer.

Genbezeichner und Symbole assoziert mit Septin 4 Proteine (SEPT4)

  • septin 4 (Sept4)
  • septin 4 (SEPT4)
  • septin 4 (PAAG_00317)
  • septin 4 (PGTG_11810)
  • septin 4 (LOC100354312)
  • ARTS Protein
  • Bh5 Protein
  • BRADEION Protein
  • CE5B3 Protein
  • DKFZp459F1329 Protein
  • DKFZp459I029 Protein
  • EG3-1RVC Protein
  • EG3RVC Protein
  • Gm11492 Protein
  • H5 Protein
  • hCDCREL-2 Protein
  • MART Protein
  • OTTMUSG00000001265 Protein
  • PNUTL2 Protein
  • RP23-168C20.1 Protein
  • SEP4 Protein
  • SEPT4 Protein

Bezeichner auf Proteinebene für Septin 4 Proteine (SEPT4)

expression gene 3 in rat visual cortex , expression gene 3-1 in rat visual cortex , peanut-like 2 , septin-4 , septin 4 , CE5B3 beta , apoptosis-related protein in the TGF-beta signaling pathway , bradeion beta , brain protein H5 , cell division control-related protein 2 , cerebral protein 7 , peanut-like protein 2 , septin-M , M-Septin , cell division control-related protein 2b , peanut-like 2 homolog , septin H5

GENE ID SPEZIES
287606 Rattus norvegicus
455160 Pan troglodytes
9100863 Paracoccidioides sp. 'lutzii' Pb01
10544005 Puccinia graminis f. sp. tritici CRL 75-36-700-3
100012173 Monodelphis domestica
100173213 Pongo abelii
100354312 Oryctolagus cuniculus
5414 Homo sapiens
18952 Mus musculus
480571 Canis lupus familiaris
538801 Bos taurus
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