anti-Selectin P Ligand (SELPLG) Antikörper

SELPLG encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. Zusätzlich bieten wir Ihnen SELPLG Kits (32) und SELPLG Proteine (13) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
SELPLG 6404 Q14242
SELPLG 20345  
SELPLG 363930  
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Top anti-SELPLG Antikörper auf antikoerper-online.de

Showing 10 out of 264 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-SELPLG Antibody Titration: 1.0 ug/ml Positive Control: Fetal Heart 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$275.00
Details
Human Kaninchen Unkonjugiert FACS, WB SELPLG Antibody (C-term)  western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the SELPLG antibody detected the SELPLG protein (arrow). SELPLG Antibody (C-term)  flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Maus FITC FACS   1 mL Anmelden zum Anzeigen 6 bis 8 Tage
$253.00
Details
Human Kaninchen Unkonjugiert EIA, FACS, WB flow cytometric analysis of Jurkat cells using SELPLG Antibody (C-term) Cat.-No AP53840PU-N (Right histogram) compared to a negative control cell (Left histogram). FITC-conjugated Goat-anti-Rabbit secondary antibodies were used for the analysis. Western blot analysis of SELPLG Antibody (C-term) Cat.-No AP53840PU-N in Jurkat cell line lysates (35ug/lane). This demonstrates the SELPLG antibody detected the SELPLG protein (arrow). 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Ratte Unkonjugiert CyTOF, ELISA, FACS, IHC, IHC (fro), IHC (p), WB Human peripheral blood lymphocytes stained with purified HECA-452, followed by anti-mouse IgG FITC Flow (Cell Surface): Cutaneous Lymphocyte Antigen (CLA) Antibody (HECA-452) [ABIN2629479] - A cell surface stain was performed on CD14+ hPBMCs with Cutaneous Lymphocyte Antigen (CLA) antibody (HECA-452) ABIN2629479 and a matched isotype control NBP2-31379. Cells were incubated in an antibody dilution of 1 ug/mL for 20 minutes at room temperature, followed by rat-Dylight 488 conjugated secondary antibody. A co-stain was performed using CD14 antibody ABIN2629478AF488. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$415.44
Details
Human Maus Unkonjugiert IHC (fro), IHC (p), WB   0.2 mg Anmelden zum Anzeigen 6 bis 8 Tage
$632.50
Details
Human Maus Unkonjugiert Func, FACS   25 μg Anmelden zum Anzeigen 6 bis 8 Tage
$176.00
Details
Human Kaninchen Unkonjugiert WB WB Suggested Anti-SELPLG Antibody Titration: 1.0 ug/ml Positive Control: Fetal Heart 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Maus APC FACS Surface staining of human peripheral blood cells with anti-human CD162 (clone TC2). 100 Tests Anmelden zum Anzeigen 5 bis 7 Tage
$366.85
Details

SELPLG Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-SELPLG Antikörper

  1. Mouse (Murine) Monoclonal SELPLG Primary Antibody für BR, FACS - ABIN1177261 : Borges, Eytner, Moll, Steegmaier, Campbell, Ley, Mossmann, Vestweber: The P-selectin glycoprotein ligand-1 is important for recruitment of neutrophils into inflamed mouse peritoneum. in Blood 1997 (PubMed)
    Show all 12 Pubmed References

  2. Human Monoclonal SELPLG Primary Antibody für CyTOF, ELISA - ABIN262947 : Walcheck, Leppanen, Cummings, Knibbs, Stoolman, Alexander, Mattila, McEver: The monoclonal antibody CHO-131 binds to a core 2 O-glycan terminated with sialyl-Lewis x, which is a functional glycan ligand for P-selectin. in Blood 2002 (PubMed)
    Show all 8 Pubmed References

  3. Human Monoclonal SELPLG Primary Antibody für Func, FACS - ABIN610433 : Connolly, Chait, Duncan, Taylor: CT-guided percutaneous needle biopsy of small lung nodules in children. in Pediatric radiology 1999 (PubMed)
    Show all 3 Pubmed References

  4. Human Monoclonal SELPLG Primary Antibody für BR, FACS - ABIN967489 : Snapp, Ding, Atkins, Warnke, Luscinskas, Kansas: A novel P-selectin glycoprotein ligand-1 monoclonal antibody recognizes an epitope within the tyrosine sulfate motif of human PSGL-1 and blocks recognition of both P- and L-selectin. in Blood 1998 (PubMed)

  5. Human Monoclonal SELPLG Primary Antibody für CyTOF, FACS - ABIN4348165 : Wake, Mori, Liu, Morioka, Teshigawara, Sakaguchi, Kuroda, Gao, Takahashi, Ohtsuka, Yoshino, Morimatsu, Nishibori: Histidine-Rich Glycoprotein Prevents Septic Lethality through Regulation of Immunothrombosis and Inflammation. in EBioMedicine 2016 (PubMed)

Weitere Antikörper gegen SELPLG Interaktionspartner

Human Selectin P Ligand (SELPLG) Interaktionspartner

  1. Results suggest that PSGL-1 may play an oncogenic role in the development of intestinal tumors, and this is likely mediated through activation of NFkB signaling by MIP (zeige TNPO1 Antikörper)-1g.

  2. c-Myc (zeige MYC Antikörper) regulates P-selectin glycoprotein ligand-1 expression in monocytes during HIV-1 infection.

  3. The percentage of CXCR3 (zeige CXCR3 Antikörper)(+) CD4 (zeige CD4 Antikörper)(+) TEM (zeige CYLD Antikörper) cells negatively correlated with the severity of the cutaneous disease in psoriasis patients. Importantly CLA(+) CD4 (zeige CD4 Antikörper)(+) TCM cells expressing CCR6 (zeige CCR6 Antikörper)(+) or CCR4 (zeige CCR4 Antikörper)(+)CXCR3 (zeige CXCR3 Antikörper)(+) negatively correlated with psoriasis severity suggesting recruitment to the skin compartment.

  4. Platelet-leukocyte aggregations increased in acute ischemic stroke patients rapidly within 3h. The I allele of PSGL-1 M62I was associated with risk of developing acute ischemic stroke, especially large artery atherosclerosis stroke and small artery occlusion stroke. Small artery occlusion stroke patients with the II genotype of PSGL-1 M62I have the higher level of platelet-neutrophil aggregates.

  5. The significant presence of CLA+ T cells and E-selectin (zeige SELE Antikörper) expressions in the OLPG suggests their involvement in the etiopathogenesis of OLP; however, only a weak correlation between CLA+ T cells and E-selectin (zeige SELE Antikörper) was observed.

  6. PSGL-1 is a novel receptor for S. pneumoniae that contributes to protection against invasive pneumococcal disease.

  7. This study provides a better understanding of the biology of P-selectin (zeige SELP Antikörper) and PSGL-1 and their roles in dissemination and resensitization of Multiple myeloma treatment.

  8. Report influence of SELPLG variation on leukocyte-platelet interactions in cardiovascular disease.

  9. E-selectin (zeige SELE Antikörper) interactions with glycoprotein ligands (CD44 (zeige CD44 Antikörper)/hematopoietic cell E-/L-selectin (zeige SELL Antikörper) ligand and PSGL-1) mediate the initial capturing of cells out of flow.

  10. CD162 staining and the staining degree, with the other standard immunohistochemical stains, were shown to be beneficial in the diagnosis of multiple myeloma disease.

Mouse (Murine) Selectin P Ligand (SELPLG) Interaktionspartner

  1. results indicate that P-selectin (zeige SELP Antikörper) deletion significantly decreases tumor stiffness in Rip1 (zeige RALBP1 Antikörper)-Tag2 mice by inhibiting LOX (zeige LOX Antikörper) expression.

  2. this study shows that PSGL-1 plays a fundamental role in balancing viral control and immunopathology and also functions to regulate T cell responses in the tumor microenvironment

  3. Psgl-1 deficiency accelerates bleomycin-induced lung fibrosis and inflammation in mice through activating the PI3K/AKT (zeige AKT1 Antikörper) axis.

  4. Circulating soluble P-selectin (zeige SELP Antikörper) must dimerize to promote inflammation and thrombosis in mice.

  5. The results from the present study suggest that activated platelets secrete Pselectin to promote cardiac inflammation and fibrosis in Ang (zeige ANG Antikörper) IIinduced hypertension.

  6. These findings indicate a novel pathway in tumor metastasis, i.e., tumor cell mediated activation of P-selectin (zeige SELP Antikörper) in platelets, followed by activation and secretion of Asm (zeige SMPD1 Antikörper) and in turn release of ceramide and tumor metastasis. The data suggest that p38 MAPK (zeige MAPK14 Antikörper) acts downstream from P-selectin (zeige SELP Antikörper) and is necessary for the secretion of Asm (zeige SMPD1 Antikörper).

  7. Psgl-1 deficiency is protective against the prothrombotic effects of IL-1beta (zeige IL1B Antikörper) .

  8. PSGL-1, CD43, and CD44 moved normally to the uropods of chemokine-stimulated C1galt1(-/-) neutrophils

  9. these results demonstrate that P-selectin (zeige SELP Antikörper) expression on ECs is regulated in part by glycosylation mechanisms and that glycosylation inhibitors efficiently reduce the adhesion of sRBCs and leukocytes to ECs.

  10. endothelial colony-forming cells interact with activated neutrophils via PSGL-1 and L-selectin (zeige SELL Antikörper)

SELPLG Antigen-Profil

Protein Überblick

This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit SELPLG

  • selectin P ligand (SELPLG) Antikörper
  • selectin, platelet (p-selectin) ligand (Selplg) Antikörper
  • selectin P ligand (Selplg) Antikörper
  • CD162 Antikörper
  • CLA Antikörper
  • Psgl-1 Antikörper
  • Psgl1 Antikörper
  • Selp1 Antikörper
  • SELPG Antikörper
  • Selpl Antikörper
  • SELPLG Antikörper

Bezeichner auf Proteinebene für SELPLG

P-selectin glycoprotein ligand 1 , cutaneous lymphocyte-associated associated antigen , selectin P ligand , P-selectin glycoprotein ligand 1 propeptide , P-selectin glycoprotein ligand-1 , leukocyte cell surface adhesion molecule , selectin, platelet (p-selectin) ligand

GENE ID SPEZIES
6404 Homo sapiens
452211 Pan troglodytes
611673 Canis lupus familiaris
617434 Bos taurus
100034025 Equus caballus
100125963 Sus scrofa
20345 Mus musculus
363930 Rattus norvegicus
100712957 Cavia porcellus
Ausgewählte Anbieter für anti-SELPLG (SELPLG) Antikörper
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