Sclerostin (SOST) ELISA Kits

Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Zusätzlich bieten wir Ihnen Sclerostin Antikörper (128) und Sclerostin Proteine (18) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
SOST 50964 Q9BQB4
SOST 74499 Q99P68
SOST 80722 Q99P67
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Top Sclerostin ELISA Kits auf antikoerper-online.de

Showing 10 out of 57 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 7.8 pg/mL 31.25-2000 pg/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 11 bis 15 Tage
874,71 €
Details
Maus 2.79 pg/mL 6.25-400 pg/mL 96 Tests Anmelden zum Anzeigen 11 bis 15 Tage
609,52 €
Details
Ratte 32 pg/mL 78-5.000 pg/mL 96 Tests Anmelden zum Anzeigen 11 bis 15 Tage
643,39 €
Details
Rind (Kuh) 15.63 pg/mL   96 Tests Anmelden zum Anzeigen 13 bis 17 Tage
874,71 €
Details
Human 0.1 ng/mL 0.312-20 ng/mL   96 Tests Anmelden zum Anzeigen 6 bis 8 Tage
554,19 €
Details
Meerschweinchen 0.1 ng/mL 0.5-10 ng/mL   96 Tests Anmelden zum Anzeigen 13 bis 17 Tage
673,47 €
Details
Kaninchen 0.1 ng/mL 0.5-10 ng/mL   96 Tests Anmelden zum Anzeigen 13 bis 17 Tage
673,47 €
Details
Ratte
0.312-20 ng/mL   96 Tests Anmelden zum Anzeigen 6 bis 8 Tage
575,14 €
Details
Affe 0.1 ng/mL 1.0-25 ng/mL   96 Tests Anmelden zum Anzeigen 13 bis 17 Tage
673,47 €
Details
Maus
0.15-10.0 ng/mL   96 Tests Anmelden zum Anzeigen 6 bis 8 Tage
679,90 €
Details

Am meisten referenzierte Sclerostin ELISA Kits

  1. Human Sclerostin ELISA Kit für Sandwich ELISA - ABIN457071 : Cidem, Usta, Karacan, Kucuk, Uludag, Gun: Effects of sex steroids on serum sclerostin levels during the menstrual cycle. in Gynecologic and obstetric investigation 2013 (PubMed)
    Show all 5 Pubmed References

  2. Human Sclerostin ELISA Kit für Sandwich ELISA - ABIN415155 : Brabnikova Maresova, Pavelka, Stepan: Acute effects of glucocorticoids on serum markers of osteoclasts, osteoblasts, and osteocytes. in Calcified tissue international 2013 (PubMed)
    Show all 3 Pubmed References

  3. Mouse (Murine) Sclerostin ELISA Kit für Sandwich ELISA - ABIN426039 : Yorgan, Peters, Jeschke, Benisch, Jakob, Amling, Schinke: The Anti-Osteoanabolic Function of Sclerostin Is Blunted in Mice Carrying a High Bone Mass Mutation of Lrp5. in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2015 (PubMed)
    Show all 2 Pubmed References

  4. Rat (Rattus) Sclerostin ELISA Kit für Sandwich ELISA - ABIN416496 : Kim, Lee, Jo, Song, Lim, Park, Bonewald, Kim: Exendin-4 increases bone mineral density in type 2 diabetic OLETF rats potentially through the down-regulation of SOST/sclerostin in osteocytes. in Life sciences 2013 (PubMed)
    Show all 2 Pubmed References

  5. Rat (Rattus) Sclerostin ELISA Kit für Sandwich ELISA - ABIN585201 : Ferreira, Ferrari, Neves, Cavallari, Dominguez, Dos Reis, Graciolli, Oliveira, Liu, Sabbagh, Jorgetti, Schiavi, Moysés: Effects of dietary phosphate on adynamic bone disease in rats with chronic kidney disease--role of sclerostin? in PLoS ONE 2013 (PubMed)

Weitere ELISA Kits für Sclerostin Interaktionspartner

Human Sclerostin (SOST) Interaktionspartner

  1. observed an association between sclerostin levels with fasting insulin (zeige INS ELISA Kits) levels and homoeostatic model assessment-insulin (zeige INS ELISA Kits) resistance, but there was no clear association with type 2 diabetes risk.

  2. Sclerostin levels in KTR are normal and influenced more by bone turnover than by eGFR (zeige EGFR ELISA Kits). Its involvement with other hormones of mineral homeostasis (FGF23 (zeige FGF23 ELISA Kits)/Klotho (zeige KL ELISA Kits) and Vitamin D) is part of the sophisticated cross-talk between bone and the kidney

  3. In chronic kidney disease, serum levels of the Wnt (zeige WNT2 ELISA Kits) inhibitors DKK1 (zeige DKK1 ELISA Kits) and sclerostin are unrelated, indicating different sites of origin and/ or different regulatory mechanisms. Sclerostin, as opposed to DKK1 (zeige DKK1 ELISA Kits), may qualify as a biomarker of chronic kidney disease-mineral and bone and mineral disorder (CKD-MBD (zeige DPEP1 ELISA Kits)), particularly in dialysis patients.

  4. Vitamin D receptor (zeige VDR ELISA Kits) agonism by paricalcitol causes a moderate increase in serum sclerostin in CKD patients, and this effect is modified by circulating pentosidine levels.

  5. SOST is frequently expressed in skeletal bone- and cartilage-forming tumors. The strong spatial correlation with bone formation and the in vitro expression patterns are in line with the known functions of SOST in nonneoplastic bone, as a feedback inhibitor on osteogenic differentiation.

  6. Intermittent compressive stress regulates Notch (zeige NOTCH1 ELISA Kits) receptor and target gene expression via the TGF-beta (zeige TGFB1 ELISA Kits) signaling pathway. Notch (zeige NOTCH1 ELISA Kits) signaling participates in TGF-beta (zeige TGFB1 ELISA Kits)-induced sclerostin expression in periodontal ligament cells.

  7. Dickkopf-1 (zeige DKK1 ELISA Kits) and sclerostin were never correlated with each other or with bone turnover markers patients with Paget's disease of bone. Sclerostin was positively correlated with age.

  8. These data suggest that sclerostin plays an important role in the bone remodeling of tooth movement.

  9. Circulating sclerostin and Dickkopf-1 (zeige DKK1 ELISA Kits) levels do not change across the menstrual cycle and do not demonstrate any relationship with estradiol in premenopausal women.

  10. SOST is expressed in the aorta and downregulated in human aortic aneurysms and atheros (zeige WNT2 ELISA Kits)clerosis, possibly because of epigenetic silencing.

Mouse (Murine) Sclerostin (SOST) Interaktionspartner

  1. In mice, sclerostin deficiency hastened reparative dentinogenesis after pulp injury, suggesting that the inhibition of sclerostin may constitute a promising therapeutic strategy for improving the healing of damaged pulps.

  2. These data suggest that sclerostin plays an important role in the bone remodeling of tooth movement.

  3. Sclerostin inhibits angiotensin II-induced aortic aneurysm and atherosclerosis via wnt (zeige WNT2 ELISA Kits) signaling pathway inhibition.

  4. Analysis of SOST expression using large minigenes reveals the MEF2C (zeige MEF2C ELISA Kits) binding site in the evolutionarily conserved region (ECR5) enhancer mediates forskolin, but not 1,25-dihydroxyvitamin D3 or TGFbeta1 (zeige TGFB1 ELISA Kits) responsiveness.

  5. removal of sclerostin appears to modestly protect the alveolar bone from resorption in this experimental setting

  6. chronic TNFalpha (tumor necrosis factor alpha (zeige TNF ELISA Kits))-dependent arthritis, fibroblast-like synoviocytes constitute a major source of sclerostin and that either the lack of sclerostin or its antibody-mediated inhibition leads to an acceleration of rheumatoid arthritis (RA)-like disease.

  7. Data show that the phenotype of Notch (zeige NOTCH1 ELISA Kits) activation in osteocytes was prevented in matrix protein 1 (Dmp1 (zeige DMP1 ELISA Kits))-Cre;Rosa(Notch (zeige NOTCH1 ELISA Kits)) mice hemizygous for the Dmp1 (zeige DMP1 ELISA Kits)-sclerostin (SOST) transgene.

  8. Results found that sclerostin enhances adipocyte differentiation in 3T3-L1 cells and reduced TAZ (zeige TAZ ELISA Kits)-responsive transcriptional activity and TAZ (zeige TAZ ELISA Kits)-responsive gene expression, indicating a role for TAZ (zeige TAZ ELISA Kits) as a regulator of adipogenesis by sclerostin.

  9. Our results suggested that sclerostin could be expressed in the liver and sustained successfully at high levels in the blood by using the PhiC31 integrase system, leading to trabecular bone loss.

  10. Sclerostin depletion enhances tibial fracture healing.

Sclerostin (SOST) Antigen-Profil

Beschreibung des Gens

Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease.

Genbezeichner und Symbole assoziert mit Sclerostin (SOST) ELISA Kits

  • sclerostin (LOC100313724) Antikörper
  • sclerostin (SOST) Antikörper
  • sclerostin (Sost) Antikörper
  • sclerostin-like (LOC100513306) Antikörper
  • 5430411E23Rik Antikörper
  • CDD Antikörper
  • LOC100313724 Antikörper
  • VBCH Antikörper

Bezeichner auf Proteinebene für Sclerostin (SOST) ELISA Kits

sclerostin , sclerosteosis

GENE ID SPEZIES
100313724 Saccoglossus kowalevskii
50964 Homo sapiens
74499 Mus musculus
80722 Rattus norvegicus
490948 Canis lupus familiaris
100730713 Cavia porcellus
282880 Bos taurus
429784 Gallus gallus
101114123 Ovis aries
100513306 Sus scrofa
Ausgewählte Anbieter für Sclerostin (SOST) ELISA Kits
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