Scavenger Receptor Class B, Member 2 Proteine (SCARB2)

The protein encoded by SCARB2 is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Zusätzlich bieten wir Ihnen SCARB2 Antikörper (71) und SCARB2 Kits (6) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
SCARB2 950 Q14108
SCARB2 12492 O35114
Ratte SCARB2 SCARB2 117106 P27615
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Showing 10 out of 14 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 46 bis 51 Tage
4.032,65 €
Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
Details
HOST_HEK-293 Cells Human Fc Tag Human recombinant SCARB2 / CD36L2 / LIMP2. The purity of rh SCARB2 /CD36L2 /LlMP2 was determined by DTT-reduced (+) SDSPAGE and staining overnight with Coomassie Blue. 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
768,26 €
Details
HOST_HEK-293 Cells Human Fc Tag Human SCARB2, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
314,29 €
Details
HOST_Human Cells Human Fc Tag,His tag 100 μg Anmelden zum Anzeigen 18 bis 20 Tage
450,00 €
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HOST_Human Cells Maus His tag 100 μg Anmelden zum Anzeigen 18 bis 20 Tage
450,00 €
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HOST_Human Human His tag   10 μg Anmelden zum Anzeigen 13 bis 15 Tage
285,71 €
Details
HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 6 bis 8 Tage
748,00 €
Details
HOST_HEK-293 Human Fc Tag   0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
538,22 €
Details

SCARB2 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , , ,
, , , , ,
Mouse (Murine) ,
,

Weitere Proteine zu Scavenger Receptor Class B, Member 2 (SCARB2) Interaktionspartnern

Zebrafish Scavenger Receptor Class B, Member 2 (SCARB2) Interaktionspartner

  1. This work describes a novel function for the Scarb2 receptor as an essential glycoprotein for notochord development.

Human Scavenger Receptor Class B, Member 2 (SCARB2) Interaktionspartner

  1. The binding of a monoclonal antibody to the apical region of SCARB2 blocks EV71 infection.

  2. The findings identify SR-BII as a functional SAA (zeige SAA1 Proteine) receptor that mediates SAA (zeige SAA1 Proteine) uptake and contributes to its proinflammatory signaling via the MAPK (zeige MAPK1 Proteine)-mediated signaling pathways.

  3. In this paper we provide an updated overview of the clinical and genetic features of SCARB2-related PME (zeige CSTB Proteine) and on the functions of the LIMP2 protein [review]

  4. neutrophils are able to drive a macrophage activation that would regulate the increase in LIMP-2 expression during the early phase of Cer (zeige CBLN1 Proteine)-induced acute pancreatitis

  5. Findings suggested that STX1B (zeige STX1B Proteine) rs4889603, FAM47E rs6812193 and SCARB2 rs6825004 do not confer a significant risk for Parkinson's disease

  6. LIMPII was increased greater than twofold in urinary microvesicles obtained from patients with idiopathic membranous nephropathy compared to microvesicles of patients with idiopathic focal segmental glomerulosclerosis and normal controls.

  7. hSR-BII (zeige CACNA1E Proteine), and to a lesser extent hSR-BI, significantly increase LPS (zeige IRF6 Proteine)-induced inflammation and contribute to LPS (zeige IRF6 Proteine)-induced tissue injury in the liver and kidney, two major organs susceptible to LPS (zeige IRF6 Proteine) toxicity.

  8. Although hrGCase cellular uptake is independent of LIMP-2, its trafficking to the lysosomes is mediated by this receptor.

  9. SNCA and SCARB2 loci are also associated with dementia with Lewy bodies, after a study-wise Bonferroni correction, although these have a different association profile than the associations reported for the same loci in Parkinson's.

  10. a novel mutation in SCARB2 as a cause of progressive myoclonus epilepsy in China

Mouse (Murine) Scavenger Receptor Class B, Member 2 (SCARB2) Interaktionspartner

  1. The findings identify SR-BII as a functional SAA (zeige SAA1 Proteine) receptor that mediates SAA (zeige SAA1 Proteine) uptake and contributes to its proinflammatory signaling via the MAPK (zeige MAPK1 Proteine)-mediated signaling pathways.

  2. AP-3 (zeige AP3B1 Proteine)-dependent LB targeting is facilitated by protein/protein interaction between LIMP-2/SCARB2 and PRDX6 (zeige PRDX6 Proteine) in vitro and in vivo

  3. Heterologous expression of the luminal domain of LIMP-2 in wild-type cells.

  4. In LIMP-2-deficient brains a significant reduction in GC activity led to lipid storage, disturbed autophagic/lysosomal function, and alpha-synuclein accumulation.

  5. absence of Limp-2 reduces inflammation in experimental crescentic glomerulonephritis with decreased macrophage and T-cell infiltration in the kidney.

  6. Limp-2 deficiency leads to a minor increase in circulating renin (zeige REN Proteine). Limp-2, however, is not required for acute or chronic stimulation of renin (zeige REN Proteine) release.

  7. The SR-BII is involved in cholesterol ester uptake for steroidogenesis and spermatogenesis in the testis.

  8. The residues between 144 and 151 are critical for SCARB2 binding to VP1 of EV71 and seven residues from the human receptor could convert murine SCARB2, an otherwise inefficient receptor, to an efficient receptor for EV71 viral infection.

  9. The data suggest that tubular proteinuria in Limp-2(-/-) mice is due to failure of endosomes containing reabsorbed proteins to fuse with lysosomes in the proximal tubule of the kidney. Failure of proteolysis is a novel mechanism for tubular proteinuria.

  10. The coiled-coil structure of LIMP-2 is required for its interaction with beta-glucocerebrosidase (zeige GBA Proteine).

SCARB2 Protein Überblick

Protein Überblick

The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit SCARB2

  • scavenger receptor class B, member 2 (scarb2)
  • scavenger receptor class B, member 2 (SCARB2)
  • scavenger receptor class B, member 2 (Scarb2)
  • 9330185J12Rik Protein
  • AMRF Protein
  • Cd36l2 Protein
  • chunp6914 Protein
  • EPM4 Protein
  • fi13c07 Protein
  • HLGP85 Protein
  • LGP85 Protein
  • LIMP-2 Protein
  • LimpII Protein
  • MLGP85 Protein
  • scarb2 Protein
  • SR-BII Protein
  • wu:fi13c07 Protein

Bezeichner auf Proteinebene für SCARB2

CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2 , CD36 antigen-like 2 , lysosome membrane protein 2 , scavenger receptor class B, member 2 , lysosome membrane protein 2-like , putative lysosomal integral membrane protein II , 85 kDa lysosomal membrane sialoglycoprotein , 85 kDa lysosomal sialoglycoprotein scavenger receptor class B, member 2 , CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2 (lysosomal integral membrane protein II) , LIMP II , lysosome membrane protein II

GENE ID SPEZIES
192340 Danio rerio
422638 Gallus gallus
461239 Pan troglodytes
549311 Xenopus (Silurana) tropicalis
699990 Macaca mulatta
100026052 Monodelphis domestica
100455864 Pongo abelii
100190617 Taeniopygia guttata
100397594 Callithrix jacchus
100470627 Ailuropoda melanoleuca
100593903 Nomascus leucogenys
533177 Bos taurus
950 Homo sapiens
12492 Mus musculus
117106 Rattus norvegicus
478435 Canis lupus familiaris
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