anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 2 (SMARCA2) Antikörper

The protein encoded by SMARCA2 is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Zusätzlich bieten wir Ihnen SMARCA2 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
SMARCA2 6595 P51531
SMARCA2 67155 Q6DIC0
SMARCA2 361745  
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Top anti-SMARCA2 Antikörper auf antikoerper-online.de

Showing 10 out of 51 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB <b>WB Suggested Anti-SMARCA2 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB Host: Rabbit Target Name: SMARCA2 Sample Type: Jurkat Whole Cell lysates Antibody Dilution: 1.0ug/ml 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB Western blot analysis of BRM expression in HepG2 (A), HeLa (B), THP1 (C), NIH3T3 (D) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Huhn Maus Unkonjugiert IF, IP, IHC, WB Western blot analysis of Brm on a HeLa cell lysate (Human cervical epitheloid carcinoma, ATCC CCL-2.2). Lane 1: 1:250, lane 2: 1:500, lane 3: 1:1000 dilution of the mouse anti-Brm antibody. Immunofluorescence staining of a rabbit lung section. 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
$168.74
Details
Human Ratte Unkonjugiert ChIP, ICC, IF, WB SMARCA2 / BRM antibody (mAb) tested by ChIP. Chromatin IP performed using the ChIP-IT® Express Kit (Catalog No. 53008) and HeLa Chromatin (1.5 x 106 cell equivalents per ChIP) using 10 µg of SMARCA2 / BRM antibody or the equivalent amount of rat IgG as a negative control. Real time, quantitative PCR (RT-qPCR) was performed on DNA purified from each of the ChIP reactions using a primer pair specific for the CD44 gene. Data are presented as Fold Enrichment of the ChIP antibody signal versus the negative control IgG using the ddCT method. SMARCA2 / BRM antibody (mAb) tested by Immunofluorescence. Formaldehyde fixed HeLa cells stained with SMARCA2 / BRM antibody at a 0.5 µg/ml dilution. 100 μg Anmelden zum Anzeigen 1 bis 2 Tage
$495.83
Details
Human Kaninchen Unkonjugiert ELISA, WB 100 μL Anmelden zum Anzeigen 16 Days
$181.73
Details
Fledermaus Kaninchen Unkonjugiert IHC (p), WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p) Immunocytochemistry/Immunofluorescence: BRM Antibody [NBP1-90015] - Staining of human cell line U-2 OS shows positivity in nucleus but not nucleoli & vesicles. Immunohistochemistry-Paraffin: BRM Antibody [NBP1-90015] - Staining of human cerebral cortex shows strong nuclear positivity in neuronal cells. 0.1 mL Anmelden zum Anzeigen 14 bis 17 Tage
$491.63
Details
Human Kaninchen Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Hund Kaninchen Unkonjugiert IHC, ELISA, WB 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$446.88
Details

SMARCA2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-SMARCA2 Antikörper

  1. Chicken Monoclonal SMARCA2 Primary Antibody für IF, IP - ABIN967938 : Muchardt, Yaniv: A human homologue of Saccharomyces cerevisiae SNF2/SWI2 and Drosophila brm genes potentiates transcriptional activation by the glucocorticoid receptor. in The EMBO journal 1993 (PubMed)
    Show all 3 Pubmed References

  2. Chicken Monoclonal SMARCA2 Primary Antibody für IF, IP - ABIN967939 : Singh, Coe, Hong: A role for retinoblastoma protein in potentiating transcriptional activation by the glucocorticoid receptor. in Nature 1995 (PubMed)
    Show all 3 Pubmed References

  3. Human Polyclonal SMARCA2 Primary Antibody für ICC, IF - ABIN4285267 : Van Houdt, Nowakowska, Sousa, van Schaik, Seuntjens, Avonce, Sifrim, Abdul-Rahman, van den Boogaard, Bottani, Castori, Cormier-Daire, Deardorff, Filges, Fryer, Fryns, Gana, Garavelli et al.: Heterozygous missense mutations in SMARCA2 cause Nicolaides-Baraitser syndrome. ... in Nature genetics 2012 (PubMed)
    Show all 2 Pubmed References

  4. Human Monoclonal SMARCA2 Primary Antibody für ChIP, ICC - ABIN2668505 : Okada, Harada, Saiwai, Nakamura, Ohkawa: Generation of a rat monoclonal antibody specific for Brm. in Hybridoma (2005) 2009 (PubMed)

Weitere Antikörper gegen SMARCA2 Interaktionspartner

Human SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 2 (SMARCA2) Interaktionspartner

  1. Two BRM promoter polymorphisms were strongly associated with hepatocellular carcinoma (HCC (zeige FAM126A Antikörper)) prognosis but were not associated with increased HCC (zeige FAM126A Antikörper) susceptibility.

  2. This de novo SMARCA2 missense mutation c.3721C>G, p.Gln1241Glu is the only reported mutation on exon 26 outside the ATPase (zeige DNAH8 Antikörper) domain of SMARCA2 to be associated with Nicolaides-Baraitser syndrome and adds to chromatin remodeling as a pathway for epileptogenesis.

  3. We conclude that their features better resemble Coffin-Siris syndrome, rather than Nicolaides-Baraitser syndrome and that these features likely arise from SMARCA2 over-dosage. Pure 9p duplications (not caused by unbalanced translocations) are rare. Copy number analysis in patients with features that overlap with Coffin-Siris syndrome is recommended to further determine their genetic aspects.

  4. BRM could activate JAK2 (zeige JAK2 Antikörper)/STAT3 (zeige STAT3 Antikörper) pathway to promote pancreatic cancer growth and chemoresistance.

  5. BRM gene mutation, chromosome 9 monosomy or BRM deletion and CpG methylation contribute collectively to the loss of BRM expression in poorly differentiated clear cell renal cell carcinoma (zeige MOK Antikörper)

  6. BRM-741 and BRM-1321 insertion polymorphisms are associated with susceptibility to cancer.

  7. BRG1 (zeige SMARCA4 Antikörper)/BRM and c-MYC (zeige MYC Antikörper) have an antagonistic relationship regulating the expression of cardiac conduction genes that maintain contractility, which is reminiscent of their antagonistic roles as a tumor suppressor and oncogene (zeige RAB1A Antikörper) in cancer.

  8. Two functional promoter BRM polymorphisms were not associated with pancreatic adenocarcinoma risk, but are strongly associated with survival.

  9. SMARCA4 (zeige SMARCA4 Antikörper) and SMARCA2 deficiency is observed in 5.1% and 4.8% of non-small cell lung cancer

  10. our data suggest that concomitant loss of SMARCA2 and SMARCA4 (zeige SMARCA4 Antikörper) is another hallmark of small cell carcinoma of the ovary, hypercalcemic type-a finding that offers new opportunities for therapeutic interventions.

Mouse (Murine) SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 2 (SMARCA2) Interaktionspartner

  1. BRG1 (zeige SMARCA4 Antikörper)/BRM and c-MYC (zeige MYC Antikörper) have an antagonistic relationship regulating the expression of cardiac conduction genes that maintain contractility, which is reminiscent of their antagonistic roles as a tumor suppressor and oncogene (zeige RAB1A Antikörper) in cancer.

  2. SWI (zeige SMARCA1 Antikörper)/SNF (zeige SNRPA Antikörper) chromatin remodeler subunits Brg1 (zeige SMARCA4 Antikörper) and Brm are expressed differentially during drug-induced liver injury and regeneration in a mouse model.

  3. these findings described a role for BRG1 (zeige SMARCA4 Antikörper) and BRM in mitochondrial quality control, by regulating mitochondrial number, mitophagy, and mitochondrial dynamics not previously recognized in the adult cardiomyocyte

  4. BRM depletion enhances the proportion of cells expressing markers of osteoblast precursors at the expense of cells able to differentiate along the adipocyte lineage.

  5. Data show that knockdown of component of chromatin remodeling complex Brm or Baf170 (zeige SMARCC2 Antikörper) at different stages promotes reprogramming.

  6. Data reveal stage-specific roles of Brm during skeletal myogenesis, via formation of repressive and activatory SWI (zeige SMARCA1 Antikörper)/SNF (zeige SNRPA Antikörper) complexes.

  7. Brm protects from UV-induced hyperplastic growth in both cutaneous and corneal keratinocytes

  8. Data suggest that Brg1 (zeige SMARCA4 Antikörper) and Brm integrate various proinflammatory cues into cell adhesion molecule (zeige MCAM Antikörper) transactivation in endothelial injury.

  9. A SMARCA2-containing residual SWI (zeige SMARCA1 Antikörper)/SNF (zeige SNRPA Antikörper) complex underlies the oncogenic activity of SMARCA4 (zeige SMARCA4 Antikörper) mutant cancers.

  10. study identifies NO and HDAC2 (zeige HDAC2 Antikörper) nitrosylation as part of a signaling pathway that regulates cortical development and the expression of Brm in neurons

SMARCA2 Antigen-Profil

Protein Überblick

The protein encoded by this gene is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. Two transcript variants encoding different isoforms have been found for this gene, which contains a trinucleotide repeat (CAG) length polymorphism.

Genbezeichner und Symbole assoziert mit SMARCA2

  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 (SMARCA2) Antikörper
  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 L homeolog (smarca2.L) Antikörper
  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 (Smarca2) Antikörper
  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 (smarca2) Antikörper
  • 2610209L14Rik Antikörper
  • BAF190 Antikörper
  • Brahma Antikörper
  • brm Antikörper
  • hBRM Antikörper
  • hSNF2a Antikörper
  • NCBRS Antikörper
  • psa-4 Antikörper
  • SNF2 Antikörper
  • SNF2alpha Antikörper
  • Snf2l2 Antikörper
  • SNF2LA Antikörper
  • Sth1p Antikörper
  • SWI2 Antikörper
  • wu:fa56c07 Antikörper
  • wu:fi27f11 Antikörper
  • zgc:66238 Antikörper

Bezeichner auf Proteinebene für SMARCA2

ATP-dependent helicase SMARCA2 , BAF190B , BRG1-associated factor 190B , SNF2-alpha , SNF2/SWI2-like protein 2 , SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a2 , global transcription activator homologous sequence , probable global transcription activator SNF2L2 , protein brahma homolog , sucrose nonfermenting 2-like protein 2 , SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 , subunit of the SWI/SNF chromatin remodeling complex , phasmid Socket Absent PSA-4

GENE ID SPEZIES
6595 Homo sapiens
403380 Xenopus laevis
396040 Gallus gallus
67155 Mus musculus
334032 Danio rerio
476335 Canis lupus familiaris
540904 Bos taurus
361745 Rattus norvegicus
100126853 Sus scrofa
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