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SPARC Related Modular Calcium Binding 1 Proteine (SMOC1)

SMOC1 encodes a multi-domain secreted protein that may have a critical role in ocular and limb development. Zusätzlich bieten wir Ihnen SMOC1 Antikörper (35) und SMOC1 Kits (1) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
Ratte SMOC1 SMOC1 314280  
SMOC1 64093 Q9H4F8
SMOC1 64075 Q8BLY1
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Showing 5 out of 6 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_Human Cells Human His tag 100 μg Anmelden zum Anzeigen 18 bis 20 Tage
450,00 €
Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 56 Days
7.380,00 €
Details
HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 6 bis 8 Tage
748,00 €
Details

SMOC1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , ,
, ,
Mouse (Murine)

Am meisten referenzierte SMOC1 Proteine

  1. Human SMOC1 Protein expressed in Human Cells - ABIN2004985 : Vannahme, Smyth, Miosge, Gösling, Frie, Paulsson, Maurer, Hartmann: Characterization of SMOC-1, a novel modular calcium-binding protein in basement membranes. in The Journal of biological chemistry 2002 (PubMed)

Weitere Proteine zu SPARC Related Modular Calcium Binding 1 (SMOC1) Interaktionspartnern

Human SPARC Related Modular Calcium Binding 1 (SMOC1) Interaktionspartner

  1. SMOC binds to Pro-EGF (zeige EGF Proteine), but does not induce Erk (zeige EPHB2 Proteine) phosphorylation via the EGFR (zeige EGFR Proteine).

  2. IL-17A (zeige IL17A Proteine) but not IL-22 (zeige IL22 Proteine) suppresses the replication of hepatitis B virus by inducing the expression of MxA (zeige MX1 Proteine) and OAS.

  3. SMOC1 provides a link between prenatal hormone exposure and digit ratio.

  4. Homozygosity mapping and subsequent targeted mutation analysis of a locus on 14q24.2 identified homozygous mutations in SMOC1 (SPARC-related modular calcium binding 1) in eight unrelated families with Waardenburg Anophthalmia syndrome.

  5. The present study thus identified SPARC related modular calcium binding 1 as a new cancer-associated protein capable of interacting with tenascin-C (zeige TNC Proteine) in vitro

  6. these findings indicate that SMOC1/Smoc1 is essential for ocular and limb development in both humans and mice.

  7. Waardenburg anophthalmia syndrome is genetically heterogeneous; a second was locus found on chromosome 14, and mutations in SMOC1 were shown also cause this syndrome.

  8. Analyzed the secretory protein profiles of BMSCs grown in osteogenic medium (OSM (zeige OSM Proteine)) and identified SPARC-related modular calcium-binding protein 1 (SMOC1), a member of the SPARC (zeige SPARC Proteine) family, as a regulator of osteoblast differentiation of BMSCs.

  9. isolation of the novel gene SMOC-1 encoding a secreted modular protein containing an EF-hand calcium-binding domain; localization within basement membranes in kidney and skeletal muscle and expression in the zona pellucida surrounding the oocyte

  10. SMOC-1 is of physiological interest because it codes a secreted glycoprotein with five domains, each containing regions homologous to those on other proteins that mediate cell-matrix interactions.

Mouse (Murine) SPARC Related Modular Calcium Binding 1 (SMOC1) Interaktionspartner

  1. SMOC1 is an activin-like kinase antagonist produced by endothelial cells that tips TGF-beta (zeige TGFB1 Proteine) signalling towards ALK1 (zeige ACVRL1 Proteine) activation

  2. The heparin-binding activity of secreted modular calcium-binding protein 1 (SMOC-1) modulates its cell adhesion properties.

  3. these findings indicate that SMOC1/Smoc1 is essential for ocular and limb development in both humans and mice.

  4. SMOC1 and SMOC2 (zeige SMOC2 Proteine) may mediate intercellular signaling and cell type-specific differentiation during gonad and reproductive tract development

  5. expression of SMOC-1 examined in the early embryo day 7, as well as in following embryonic stages on days 12, 14, 16 & 18; broad and organ-specific distribution suggests multifunctional roles of SMOC-1 during mouse embryogenesis

SMOC1 Protein Überblick

Protein Überblick

This gene encodes a multi-domain secreted protein that may have a critical role in ocular and limb development. Mutations in this gene are associated with microphthalmia and limb anomalies. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit SMOC1

  • SPARC related modular calcium binding 1 (Smoc1)
  • SPARC related modular calcium binding 1 (SMOC1)
  • SPARC related modular calcium binding 1 (smoc1)
  • 2600002F22Rik Protein
  • AI848508 Protein
  • OAS Protein
  • SMOC-1 Protein
  • SMOC1 Protein
  • SRG Protein
  • XSMOC-1 Protein

Bezeichner auf Proteinebene für SMOC1

SPARC-related modular calcium binding protein 1 , SPARC-related modular calcium-binding protein 1 , SPARC related modular calcium binding 1 , secreted modular calcium-binding protein 1 , secreted modular calcium-binding 1 , SMOC-1 , SPARC-related gene protein , SPARC-related protein , secreted modular calcium binding protein 1

GENE ID SPEZIES
314280 Rattus norvegicus
453002 Pan troglodytes
480373 Canis lupus familiaris
508379 Bos taurus
768688 Gallus gallus
100145733 Xenopus (Silurana) tropicalis
100529120 Danio rerio
64093 Homo sapiens
64075 Mus musculus
Ausgewählte Anbieter für SMOC1 Proteine (SMOC1)
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