anti-SP110 Nuclear Body Protein (SP110) Antikörper

The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. Zusätzlich bieten wir Ihnen SP110 Nuclear Body Protein Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
SP110 3431 Q9HB58
SP110 109032 Q8BVK9
SP110 301570 Q3KRF1
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Top anti-SP110 Nuclear Body Protein Antikörper auf antikoerper-online.de

Showing 10 out of 67 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Hund Kaninchen Unkonjugiert WB <b>WB Suggested Anti-SP110 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>MCF7 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Pferd Kaninchen Unkonjugiert WB <b>WB Suggested Anti-SP110 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert WB <b>WB Suggested Anti-SP110 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>HT1080 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB   100 μg Anmelden zum Anzeigen 15 bis 19 Tage
$466.62
Details
Human Kaninchen Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 15 bis 19 Tage
$466.62
Details
Hund Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB   0.1 mg Anmelden zum Anzeigen 12 bis 15 Tage
$375.38
Details
Human Kaninchen Unkonjugiert EIA, WB   0.1 mg Anmelden zum Anzeigen 12 bis 15 Tage
$375.38
Details
Human Ziege Unkonjugiert IHC (p) Spleen, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) Tonsil, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$451.00
Details
Human Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$507.83
Details

SP110 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
Human , ,
, ,
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Mouse (Murine)


Rat (Rattus)


Am meisten referenzierte anti-SP110 Nuclear Body Protein Antikörper

  1. Human Polyclonal SP110 Primary Antibody für IHC, ELISA - ABIN1002686 : Bloch, Nakajima, Gulick, Chiche, Orth, de La Monte, Bloch: Sp110 localizes to the PML-Sp100 nuclear body and may function as a nuclear hormone receptor transcriptional coactivator. in Molecular and cellular biology 2000 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal SP110 Primary Antibody für ELISA, WB - ABIN1002687 : Pan, Yan, Rojas, Shebzukhov, Zhou, Kobzik, Higgins, Daly, Bloom, Kramnik: Ipr1 gene mediates innate immunity to tuberculosis. in Nature 2005 (PubMed)
    Show all 3 Pubmed References

Weitere Antikörper gegen SP110 Nuclear Body Protein Interaktionspartner

Cow (Bovine) SP110 Nuclear Body Protein (SP110) Interaktionspartner

  1. SP110 as a novel susceptibility gene for Mycobacterium avium subspecies paratuberculosis infection in cattle.

Horse (Equine) SP110 Nuclear Body Protein (SP110) Interaktionspartner

  1. Novel splice variants of SP110 in the horse have an activation effect on macrophages.

Human SP110 Nuclear Body Protein (SP110) Interaktionspartner

  1. Using mouse models and genetic characteristics of human patients the role of SP110b was studied to determine its role in controlling host immunity and susceptibility to TB by modulating nuclear factor-kappaB (NF-kappaB (zeige NFKB1 Antikörper)) activity resulting in down regulation of TNF-alpha (zeige TNF Antikörper) production and upregulation of NF-kappaB (zeige NFKB1 Antikörper)-induced antipoptotic gene expression suppressing IFN-gamma (zeige IFNG Antikörper)-mediated monocyte and/or macrophage cell death.

  2. The results indicated that both the heterozygous genotype GC and homozygous genotype CC in rs3809849 in MYBBP1A (zeige MYBBP1A Antikörper) had significant effects on the risk of pulmonary tuberculosis, and heterozygous genotype CT in rs9061 in SP110 also had similar effects.

  3. Results show that SP110 variants were associated with increased susceptibility to both pulmonary and extra-pulmonary tuberculosis in the Vietnamese patients. Those variants may influence macrophage signaling responses and apoptosis during the infection.

  4. Study suggests that a combination of SP110 and MYBBP1A gene polymorphisms may serve as a novel marker for identifying the risk of developing TB in the Chinese Han population.

  5. Several SNPs in Sp110 are risk factors for susceptibility to tuberculosis in Chongqing Han People.

  6. In a pooled analysis of 10,624 cases of tuberculosis, there was not a significant association between polymorphisms in the SP110 gene and disease susceptibility. [Meta-analysis]

  7. Genotyped 20 SNPs located in the SP110 gene, for the first time in a South East Asian cohort from Indonesia.Our study did not reveal any statistically significant associations between SP110 SNPs and pulmonary TB.

  8. a range of mutations in SP110 that cause decreased SP110 protein levels and impaired late B-cell differentiation cause veno-occlusive disease with immunodeficiency syndrome.

  9. the results might indicate a role of SP110 variants in extrapulmonary tuberculosis rather than PTB (zeige PTBP1 Antikörper).

  10. This study demonstrates that genotypes and haplotypes of SP110 might be associated with susceptibility to tuberculosis in Chinese population.

Mouse (Murine) SP110 Nuclear Body Protein (SP110) Interaktionspartner

  1. mechanistic studies revealed that an arginine/lysine-rich element within the DNA-binding domain (SAND domain) is critical for Ipr1 binding to the importin protein receptor NPI-1 (zeige KPNA1 Antikörper), demonstrating that this element plays an essential role in mediating the nuclear localization of Ipr1 protein

  2. Using mouse models and genetic characteristics of human patients the role of SP110b was studied to determine its role in controlling host immunity and susceptibility to TB by modulating nuclear factor-kappaB (NF-kappaB (zeige NFKB1 Antikörper)) activity resulting in down regulation of TNF-alpha (zeige TNF Antikörper) production and upregulation of NF-kappaB (zeige NFKB1 Antikörper)-induced antipoptotic gene expression suppressing IFN-gamma (zeige IFNG Antikörper)-mediated monocyte and/or macrophage cell death.

  3. These findings not only reveal the transcriptional basis of Sp110-mediated macrophage resistance to Mtb (zeige NCAPG2 Antikörper), but also suggest potential regulatory roles for Sp110 related to inflammatory responses, miRNA profiles, and the intracellular growth of Mtb (zeige NCAPG2 Antikörper).

  4. Ipr1 might be involved in apoptosis pathway via MYBBP1A (zeige MYBBP1A Antikörper).

  5. identification and analysis of the genes Sp100 (zeige SP100 Antikörper), Csprs, and Ifi75 in two members of the genus Mus (zeige TRPV6 Antikörper), M. musculus and M. caroli

  6. data indicate that the Ipr1 gene product might have a previously undocumented function in integrating signals generated by intracellular pathogens with mechanisms controlling innate immunity, cell death and pathogenesis

SP110 Nuclear Body Protein (SP110) Antigen-Profil

Protein Überblick

The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. This gene is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation. Alternative splicing has been observed for this gene and three transcript variants, encoding distinct isoforms, have been identified.

Genbezeichner und Symbole assoziert mit SP110

  • SP110 nuclear body protein (SP110) Antikörper
  • Sp110 nuclear body protein (Sp110) Antikörper
  • SP110 nuclear body protein (Sp110) Antikörper
  • 52kDa Antikörper
  • 5031415C07Rik Antikörper
  • 5830484A20Rik Antikörper
  • ENSMUSG00000075603 Antikörper
  • IFI41 Antikörper
  • Ifi75 Antikörper
  • Ipr1 Antikörper
  • SP110 Antikörper
  • VODI Antikörper

Bezeichner auf Proteinebene für SP110

SP110 nuclear body protein , sp110 nuclear body protein-like , interferon-induced protein 41, 30kD , interferon-induced protein 41/75 , interferon-induced protein 75, 52kD , phosphoprotein 41 , phosphoprotein 75 , sp110 nuclear body protein , speckled 110 kDa , transcriptional coactivator Sp110 , intracellular pathogen resistance 1 , intracellular pathogen resistance protein 1

GENE ID SPEZIES
470728 Pan troglodytes
515204 Bos taurus
100056977 Equus caballus
100391349 Callithrix jacchus
100452909 Pongo abelii
100585660 Nomascus leucogenys
3431 Homo sapiens
100686387 Canis lupus familiaris
109032 Mus musculus
301570 Rattus norvegicus
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