SIN3 Transcription Regulator Homolog B (Yeast) Proteine (SIN3B)

Acts as a transcriptional repressor. Zusätzlich bieten wir Ihnen SIN3 Transcription Regulator Homolog B (Yeast) Antikörper (54) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
SIN3B 23309 O75182
Ratte SIN3B SIN3B 683381  
SIN3B 20467 Q62141
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 66 Days
10.536,00 €
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Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 66 Days
10.536,00 €
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HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
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SIN3B Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
,
Mouse (Murine)

Weitere Proteine zu SIN3 Transcription Regulator Homolog B (Yeast) (SIN3B) Interaktionspartnern

Human SIN3 Transcription Regulator Homolog B (Yeast) (SIN3B) Interaktionspartner

  1. these results suggest that stress-induced Sin3B activation is p53 (zeige TP53 Proteine)-dependent and is essential for p53 (zeige TP53 Proteine)-mediated repression of its selective target genes.

  2. The study suggests that the difference in the conformation of native state structure or structural flexibility of the paired amphi pathic helices (PAH) domains of Sin3B might be responsible for interacting with specific binding partners.

  3. A conserved Myc (zeige MYC Proteine) region (amino acids 186-203) is required for the interaction with Sin3 proteins. Histone deacetylase 1 (zeige HDAC1 Proteine) is recruited to Myc (zeige MYC Proteine)-Sin3b complexes, and its deacetylase activity is required for the effects of Sin3b on Myc (zeige MYC Proteine).

  4. this study highlights an essential role for Sin3B in IFN-c induced COL1A2 (zeige COL1A2 Proteine) repression in smooth muscle cells.

  5. Senescence-associated SIN3B promotes inflammation and pancreatic cancer progression

  6. the essential role of Sin3B as an important associate of p53 (zeige TP53 Proteine) in mediating the cellular responses to stress and in the transcriptional repression of genes

  7. identification of a mammalian complex containing the corepressor Sin3B, the histone deacetylase HDAC1 (zeige HDAC1 Proteine), Mrg15 (zeige MORF4L1 Proteine), and the PHD (zeige PDC Proteine) finger-containing Pf1

  8. disruption of the function of a specific Sin3A (zeige SIN3A Proteine)/B domain leads to epigenetic reprogramming and derepression of specific subsets of genes in breast cancer cells

  9. SMAR1 (zeige BANP Proteine) regulates cyclin D1 (zeige CCND1 Proteine) by modification of chromatin through the SIN3/histone deacetylase 1 (zeige HDAC1 Proteine) complex

  10. The interaction between SIN3B and ETO (zeige RUNX1T1 Proteine) required an intact amino-terminus of ETO (zeige RUNX1T1 Proteine) and the NHR2 domain.

Mouse (Murine) SIN3 Transcription Regulator Homolog B (Yeast) (SIN3B) Interaktionspartner

  1. these results identify Sin3B as a novel and critical regulator of hematopoietic stem cells functions.

  2. adrenergic stimulation induced complex formation between Ifrd1 (zeige IFRD1 Proteine), Sp1 (zeige SP1 Proteine) and mSIN3B, which is a component of the SIN (zeige POLR3E Proteine) complex containing histone deacetylase (zeige HDAC1 Proteine), in brown adipocytes. These findings, therefore, suggest that Ifrd1 (zeige IFRD1 Proteine) could be a pivotal negative regulator of sympathetic regulation of thermogenic and mitochondrial gene expression in brown adipocytes by interacting with Sp1 (zeige SP1 Proteine) and the mSIN3 complex.

  3. Sin3B is required for the senescent phenotype and elevated levels of reactive oxygen species elicited upon Bmi-1 (zeige BMI1 Proteine) depletion.

  4. Senescence-associated SIN3B promotes inflammation and pancreatic cancer progression

  5. interaction with Sin3B influences Na(v)-channel trafficking or stability in the membrane.

  6. Sin3 has an important role in the regulation of cell cycle kinetics of the myogenic progenitor cell population

  7. Results describe a novel transcriptional role for Sin3A and Sin3B proteins associated with maintenance of differentiated muscle cells.

  8. RNF220 was identified as a novel ubiquitin ligase for Sin3B.

  9. ESET (zeige SETDB1 Proteine) histone methyltransferase can form a large, multi-protein complex(es) with mSin3A/B co-repressors and HDAC1 (zeige HDAC1 Proteine)/2 that participates in multiple pathways of transcriptional repression.

  10. When tethered in cis (zeige CISH Proteine) to DNA, the transcriptional corepressor mSin3B inhibits polyomavirus (Py) ori-dependent DNA replication in vivo.

SIN3 Transcription Regulator Homolog B (Yeast) (SIN3B) Protein Überblick

Protein Überblick

Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription (By similarity).

Genbezeichner und Symbole assoziert mit SIN3B

  • SIN3 homolog B, transcription regulator (yeast) (sin3b)
  • SIN3 transcription regulator family member B (SIN3B)
  • SIN3 transcription regulator homolog B (sin3b)
  • SIN3 transcription regulator homolog B (yeast) (SIN3B)
  • SIN3 transcription regulator homolog B (yeast) (Sin3b)
  • transcriptional regulator, SIN3B (yeast) (Sin3b)
  • 2810430C10Rik Protein
  • fj63d08 Protein
  • si:dkey-6n6.6 Protein
  • wu:fj63d08 Protein

Bezeichner auf Proteinebene für SIN3B

paired amphipathic helix protein Sin3b , SIN3 homolog B, transcription regulator , SIN3 homolog B, transcriptional regulator , SIN3 transcription regulator homolog B , histone deacetylase complex subunit Sin3b , transcriptional corepressor Sin3b , transcriptional regulator, SIN3B , transcriptional regulator, SIN3 yeast homolog B

GENE ID SPEZIES
560837 Danio rerio
23309 Homo sapiens
100036844 Xenopus laevis
520505 Bos taurus
683381 Rattus norvegicus
420140 Gallus gallus
610198 Canis lupus familiaris
20467 Mus musculus
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