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SH3RF1 encodes a protein containing an N-terminus RING-finger, four SH3 domains, and a region implicated in binding of the Rho GTPase Rac. Zusätzlich bieten wir Ihnen SH3RF1 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.
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Human Monoclonal SH3RF1 Primary Antibody für WB - ABIN393739
Rose, Behm, Drgon, Johnson, Uhl: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. in Molecular medicine (Cambridge, Mass.) 2010
Zeige alle 5 Referenzen für 393739
Cow (Bovine) Polyclonal SH3RF1 Primary Antibody für WB - ABIN2774771
Lyons, Thorburn, Ryan, Thorburn, Anderson, Kassenbrock: Regulation of the Pro-apoptotic scaffolding protein POSH by Akt. in The Journal of biological chemistry 2007
Human Polyclonal SH3RF1 Primary Antibody für ELISA, WB - ABIN566141
Wilhelm, Xu, Kukekov, Gire, Greene: Proapoptotic Nix activates the JNK pathway by interacting with POSH and mediates death in a Parkinson disease model. in The Journal of biological chemistry 2007
Human Monoclonal SH3RF1 Primary Antibody für ELISA, WB - ABIN566142
Wilhelm, Kukekov, Schmit, Biagas, Sproul, Gire, Maes, Xu, Greene: Sh3rf2/POSHER protein promotes cell survival by ring-mediated proteasomal degradation of the c-Jun N-terminal kinase scaffold POSH (Plenty of SH3s) protein. in The Journal of biological chemistry 2012
the active JNK (zeige MAPK8 Antikörper) signaling complex formed of POSH and the JNK (zeige MAPK8 Antikörper) module is essential for the expression of anterior neural genes and apoptosis in anterior development
Data show that the two N-terminal SH3 domains of SH3 domain containing ring finger 1 (SH3RF1) protein interact with FAT1 (zeige FAT1 Antikörper) protein.
We found a genome-wide significant association for rs2282987 in CDK6 (zeige CDK6 Antikörper) and a consistent association for rs2706748 in SH3RF1 .
The data presented here define POSH and Siah2 (zeige SIAH2 Antikörper) as important mediators of death receptor mediated apoptosis and suggest targeting the interaction of these two E3 ligases is a promising novel cancer therapeutic strategy.
POSH promotes cell survival in Drosophila and in human rheumatoid arthritis synovial fibroblasts
POSH disassociates from the JNK (zeige MAPK8 Antikörper) complex after phosphorylation of MLK3 (zeige MAP3K11 Antikörper) by Akt2 (zeige AKT2 Antikörper), which leads to down-regulation of the JNK (zeige MAPK8 Antikörper) signaling pathway
Results identified ALIX (zeige PDCD6IP Antikörper) as an ubiquitination substrate of POSH and indicate that POSH and ALIX (zeige PDCD6IP Antikörper) cooperate to facilitate efficient virus release.
POSH inhibits ROMK (zeige KCNJ1 Antikörper) channels by enhancing dynamin (zeige DNM1 Antikörper)-dependent and clathrin-independent endocytosis and by stimulating ubiquitination of ROMK (zeige KCNJ1 Antikörper) channels.
this study shows that POSH is essential for the integration of cell-type-specific signals that regulate the differentiation, survival, and function of T cells
identify plenty of SH3 (POSH) and JNK-interacting protein 1 (JIP-1 (zeige MAPK8IP1 Antikörper)) as a multiprotein scaffold network for TCR-mediated JNK1 (zeige MAPK8 Antikörper) activation in CD8 (zeige CD8A Antikörper)(+) T cells.
a mechanism by which POSH regulates the localization of activated Rac1 and F-actin assembly to control PCDLP formation and subsequent somal translocation of migratory neurons.
An intracellular signaling pathway for process outgrowth inhibition by Nogo66 implicates the POSH complex as a therapeutic target to enhance axon outgrowth and plasticity in the injured central nervous system.
Siah1 (zeige SIAH1 Antikörper) is a binding partner for POSH (plenty of SH3s), a scaffold component of the apoptotic JNK (zeige MAPK8 Antikörper) pathway
POSH and JIPs directly associate with one another to form a multiprotein complex, PJAC (POSH-JIP (zeige SMAD4 Antikörper) apoptotic complex), that includes all of the known kinase components of the pathway.
Results suggest that the molecular scaffold protein POSH assembles an inhibitory complex that links to the actin-myosin network to regulate neuronal process outgrowth.
This gene encodes a protein containing an N-terminus RING-finger, four SH3 domains, and a region implicated in binding of the Rho GTPase Rac. Via the RING-finger, the encoded protein has been shown to function as an ubiquitin-protein ligase involved in protein sorting at the trans-Golgi network. The encoded protein may also act as a scaffold for the c-Jun N-terminal kinase signaling pathway, facilitating the formation of a functional signaling module.
SH3 multiple domains 2
, SH3 domain containing ring finger 1
, putative E3 ubiquitin-protein ligase SH3RF1
, plenty of SH3s
, SH3 domain-containing RING finger protein 1
, E3 ubiquitin-protein ligase SH3RF1
, SH3 multiple domains protein 2
, plenty of SH3 domains
, ring finger protein 142
, putative scaffolding protein POSH