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SH2 Domain Protein 1A (SH2D1A) ELISA Kits

a component of amyloid P. Zusätzlich bieten wir Ihnen SH2 Domain Protein 1A Antikörper (6) und und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
SH2D1A 29339 P23680
SH2D1A 4068 O60880
SH2D1A 20400 O88890
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Top SH2 Domain Protein 1A ELISA Kits auf antikoerper-online.de

Showing 3 out of 12 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 0.67 ng/mL 1.56-100 ng/mL 96 Tests Anmelden zum Anzeigen 7 bis 10 Tage
703,70 €
Details
Maus 1.37 ng/mL 3.12-200 ng/mL 96 Tests Anmelden zum Anzeigen 7 bis 10 Tage
474,08 €
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Ratte 2.44 ng/mL 6.25-400 ng/mL 96 Tests Anmelden zum Anzeigen 7 bis 10 Tage
764,02 €
Details

Am meisten referenzierte SH2 Domain Protein 1A ELISA Kits

  1. Human SH2D1A ELISA Kit für Sandwich ELISA - ABIN414747 : Oberbach, Blüher, Wirth, Till, Kovacs, Kullnick, Schlichting, Tomm, Rolle-Kampczyk, Murugaiyan, Binder, Dietrich, von Bergen: Combined proteomic and metabolomic profiling of serum reveals association of the complement system with obesity and identifies novel markers of body fat mass changes. in Journal of proteome research 2011 (PubMed)
    Zeige alle 3 Referenzen für ABIN414747

Weitere ELISA Kits für SH2 Domain Protein 1A Interaktionspartner

Human SH2 Domain Protein 1A (SH2D1A) Interaktionspartner

  1. High LAT1 expression correlated with significantly shorter prostate specific antigen recurrence-free survival in patients receiving androgen deprivation therapy

  2. We describe here a novel c.137+5G > A intronic mutation in the SH2D1A gene of the signaling lymphocyte activation molecule (SLAM (zeige SLAMF1 ELISA Kits))-associated protein (SAP) in association with Epstein-Barr virus (EBV)-induced fatal infectious mononucleosis (FIM (zeige ZMYM2 ELISA Kits)) in an 8-year-old male patient and his 3-year-old step brother. The mother and the maternal grandmother of the boys are healthy and heterozygous for this sequence variant.

  3. In addition to their role in NK cell activation by hematopoietic cells, the SLAM-SAP-SHP1 pathways influence responsiveness toward nonhematopoietic targets by a process akin to NK cell 'education'.

  4. The mutation c.131G>A in this patient was found in combination with a second SH2D1A mutation

  5. Study of SAP (zeige APCS ELISA Kits) expression is specific but may have insufficient sensitivity for screening XLP1 as a single tool; however, combination with 2B4 (zeige CD244 ELISA Kits) functional assay allows identification of all cases

  6. Molecular dynamics analysis revealed that mutant R32Q and T53I structures of SAP (zeige APCS ELISA Kits) exhibited structural variation with respect to their backbone atoms before and after binding with the unphosphorylated SLAM (zeige SLAMF1 ELISA Kits) peptide.

  7. Signaling lymphocytic activation molecule (SLAM)/SLAM (zeige SLAMF1 ELISA Kits)-associated protein pathway regulates human B-cell tolerance.

  8. In patients suffering from X-linked lymphoproliferative disease (XLP1), SAP (zeige APCS ELISA Kits) is nonfunctional, not only abolishing the activating function of 2B4 (zeige CD244 ELISA Kits), but rendering this receptor inhibitory.

  9. our data reveal how SAP (zeige APCS ELISA Kits) nucleates a previously unknown signaling complex involving NTB-A (zeige SLAMF6 ELISA Kits) and LCK (zeige LCK ELISA Kits) to potentiate restimulation-induced cell death of activated human T cells.

  10. SAP (zeige APCS ELISA Kits) is a new actor downstream of PECAM-1 (zeige PECAM1 ELISA Kits) and its binding regulates PECAM-1 (zeige PECAM1 ELISA Kits) mediated cell adhesion.

Mouse (Murine) SH2 Domain Protein 1A (SH2D1A) Interaktionspartner

  1. SAP (zeige APCS ELISA Kits) is an essential molecule for autoimmune antibody production.

  2. In addition to their role in NK cell activation by hematopoietic cells, the SLAM-SAP-SHP1 pathways influence responsiveness toward nonhematopoietic targets by a process akin to NK cell 'education'.

  3. SLAM (zeige SLAMF1 ELISA Kits)-SAP (zeige APCS ELISA Kits) signaling promotes differentiation of IL-17 (zeige IL17A ELISA Kits)-producing T cells and progression of experimental autoimmune encephalomyelitis.

  4. these data suggest that SAP (zeige APCS ELISA Kits) is critical for regulating type II NKT (zeige CTSL1 ELISA Kits) cell responses.

  5. functional analysis in vitro indicates that SAP-2 is a non-functional isoform due to decreased protein stability

  6. Here we report that B cell intrinsic responses to haptenated protein antigens are impaired in SAP (zeige APCS ELISA Kits)-/- mice and in Rag-/- mice into which B cells derived from SAP (zeige APCS ELISA Kits)-/- mice together with wt CD4 (zeige CD4 ELISA Kits)+ T cells had been transferred.

  7. SAP (zeige APCS ELISA Kits) plays an essential role in CIA (zeige NCOA5 ELISA Kits) because of Fyn (zeige FYN ELISA Kits)-independent and Fyn (zeige FYN ELISA Kits)-dependent effects on TFH cells and, possibly, other T cell types.

  8. SAP (zeige APCS ELISA Kits) was required not only for the initiation but also for the progression of primary T cell-driven B cell responses to haptens.

  9. Loss of SAP (zeige APCS ELISA Kits) expression is associated with invariant NKT (zeige CTSL1 ELISA Kits) cell cytotoxicity and defective lytic synapse formation.

  10. SAP (zeige APCS ELISA Kits) is required for the development of innate phenotype in H2-M3--restricted Cd8 (zeige CD8A ELISA Kits)(+) T cells.

SH2 Domain Protein 1A (SH2D1A) Antigen-Profil

Beschreibung des Gens

This gene encodes a protein that plays a major role in the bidirectional stimulation of T and B cells. This protein contains an SH2 domain and a short tail. It associates with the signaling lymphocyte-activation molecule, thereby acting as an inhibitor of this transmembrane protein by blocking the recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to its docking site. This protein can also bind to other related surface molecules that are expressed on activated T, B and NK cells, thereby modifying signal transduction pathways in these cells. Mutations in this gene cause lymphoproliferative syndrome X-linked type 1 or Duncan disease, a rare immunodeficiency characterized by extreme susceptibility to infection with Epstein-Barr virus, with symptoms including severe mononucleosis and malignant lymphoma. Multiple transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit SH2D1A

  • amyloid P component, serum (Apcs) Antikörper
  • SH2 domain containing 1A (SH2D1A) Antikörper
  • SH2 domain containing 1A (Sh2d1a) Antikörper
  • SH2 domain protein 1A (Sh2d1a) Antikörper
  • DSHP Antikörper
  • EBVS Antikörper
  • Gm686 Antikörper
  • IMD5 Antikörper
  • LYP Antikörper
  • MTCP1 Antikörper
  • RGD1562408 Antikörper
  • SAP Antikörper
  • SAP/SH2D1A Antikörper
  • XLP Antikörper
  • XLPD Antikörper

Bezeichner auf Proteinebene für SH2D1A

serum amyloid P-component , Duncan disease SH2-protein , SH2 domain-containing protein 1A , SLAM associated protein/SH2 domain protein 1A , SLAM-associated protein , T cell signal transduction molecule SAP , T-cell signal transduction molecule SAP , signaling lymphocyte activation molecule-associated protein , signaling lymphocytic activation molecule-associated protein , SH2 domain protein 1A , Duncan disease homolog

GENE ID SPEZIES
29339 Rattus norvegicus
4068 Homo sapiens
501502 Rattus norvegicus
20400 Mus musculus
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