SET and MYND Domain Containing 3 Proteine (SMYD3)

SMYD3 encodes a histone methyltransferase which functions in RNA polymerase II complexes by an interaction with a specific RNA helicase. Zusätzlich bieten wir Ihnen SMYD3 Antikörper (75) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
SMYD3 64754 Q9H7B4
SMYD3 69726 Q9CWR2
Ratte SMYD3 SMYD3 498295  
Direkt bei antikoerper-online bestellen
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Online bestellen
  • orders@antikoerper-online.de

Top SMYD3 Proteine auf antikoerper-online.de

Showing 7 out of 8 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$7,759.50
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$7,759.50
Details
Baculovirus infected Insect Cells Human GST tag 50 μg Anmelden zum Anzeigen 20 bis 21 Tage
$382.80
Details
Human Cells Human DYKDDDDK Tag,His tag 50 μg Anmelden zum Anzeigen 20 bis 21 Tage
$382.80
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$405.71
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 10 bis 12 Tage
$785.40
Details
Baculovirus Human DYKDDDDK Tag Recombinant SMYD3 protein gel. SMYD3 protein was run on an SDS-PAGE gel and stained with Coomassie blue. SMYD3 activity assay. HMT assay measuring the activity of Recombinant SMYD3. Activity was detected by fluorography. 20 μg Anmelden zum Anzeigen 1 bis 2 Tage
$466.67
Details

SMYD3 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , , ,
, , , ,
Mouse (Murine)

Weitere Proteine zu SET and MYND Domain Containing 3 (SMYD3) Interaktionspartnern

Human SET and MYND Domain Containing 3 (SMYD3) Interaktionspartner

  1. SMYD3 enhances tumorigenicity in esophageal squamous cell carcinoma by enhancing transcription of ezrin (zeige EZR Proteine) and LOXL2 (zeige LOXL2 Proteine), which are involved in proliferation, migration, and invasion.

  2. SMYD3-mediated H2A.Z (zeige H2AFZ Proteine).1K101 dimethylation activates cyclin A1 (zeige CCNA1 Proteine) expression and contributes to driving the proliferation of breast cancer cells.

  3. Substrate crevices of Smyd2 (zeige SMYD2 Proteine) and Smyd3 show distinct features in terms of spatial, hydration, and electrostatic properties that emphasize their characteristic modes of substrates interaction and entry pathways for inhibitor binding.

  4. VNTR genotype 3/3 of the SMYD3 gene was associated with the risk of ovarian cancer.

  5. The present results suggest that NS5A interacts with SMYD3 and induces AP-1 (zeige FOSB Proteine) activation, possibly by facilitating binding between HSP90 (zeige HSP90 Proteine) and SMYD3. This may be a novel mechanism of AP-1 (zeige FOSB Proteine) activation in HCV-infected cells.

  6. SMYD3 physically interacts with the promoter of BCLAF1 and upregulates its expression by accumulating di- and trimethylation of H3K4 at the BCLAF1 locus. SMYD3 overexpression in bladder cancer cells promotes autophagy activation.

  7. High expression of SMYD3 is associated with chronic lymphocytic leukemia.

  8. results clearly revealed structural determinants for the substrate preference of SMYD3 and provided mechanistic insights into lysine methylation of MAP3K2 (zeige MAP3K2 Proteine).

  9. A novel HBx-interacting protein (zeige HBXIP Proteine), SMYD3, was identified, leading to proposal of a novel mechanism of AP-1 (zeige FOSB Proteine) activation in HBV-infected cells.

  10. Postulate that AdoMet (zeige MAT1A Proteine) cofactor acts like a key and locks Smyd3 in a closed conformation.

Mouse (Murine) SET and MYND Domain Containing 3 (SMYD3) Interaktionspartner

  1. The transcription-potentiating function of Smyd3 is restricted to a particular set of genes.

  2. Epigenetic control of Foxp3 (zeige FOXP3 Proteine) by SMYD3 H3K4 histone methyltransferase controls iTreg development and regulates pathogenic T-cell responses during pulmonary viral infection.

  3. These findings indicate that SMYD3 plays an important role in early embryonic lineage commitment and peri (zeige POSTN Proteine)-implantation development through the activation of lineage-specific genes.

  4. represent the proof of principle that SMYD3 is a druggable target

  5. methylation of MAP3K2 by SMYD3 increases MAP kinase signalling and promotes the formation of Ras-driven carcinomas

  6. SMYD3 depletion prevents muscle loss and fiber size decrease; findings reveal a mechanistic link between SMYD3/BRD4 (zeige BRD4 Proteine)-dependent transcriptional regulation, muscle mass determination, and skeletal muscle atrophy

  7. SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells.

SMYD3 Protein Überblick

Protein Überblick

This gene encodes a histone methyltransferase which functions in RNA polymerase II complexes by an interaction with a specific RNA helicase. Multiple transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit SMYD3

  • SET and MYND domain containing 3 (SMYD3)
  • SET and MYND domain containing 3 (Smyd3)
  • 2410008A19Rik Protein
  • bA74P14.1 Protein
  • KMT3E Protein
  • Zmynd1 Protein
  • ZNFN3A1 Protein

Bezeichner auf Proteinebene für SMYD3

SET and MYND domain containing 3 , SET and MYND domain-containing protein 3 , bA74P14.1 (novel protein) , histone-lysine N-methyltransferase SMYD3 , zinc finger MYND domain-containing protein 1 , zinc finger protein, subfamily 3A (MYND domain containing), 1 , zinc finger, MYND domain containing 1 , SET and MYND domain-containing 3

GENE ID SPEZIES
100347516 Oryctolagus cuniculus
64754 Homo sapiens
100294707 Sus scrofa
616050 Bos taurus
69726 Mus musculus
498295 Rattus norvegicus
Ausgewählte Anbieter für SMYD3 Proteine (SMYD3)
Haben Sie etwas anderes gesucht?