Runt-Related Transcription Factor 2 (RUNX2) ELISA Kits

RUNX2 is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. Zusätzlich bieten wir Ihnen RUNX2 Antikörper (236) und RUNX2 Proteine (12) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
RUNX2 12393 Q08775
RUNX2 860 Q13950
RUNX2 367218  
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Top RUNX2 ELISA Kits auf antikoerper-online.de

Showing 10 out of 47 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 0.054 ng/mL 0.15-10 ng/mL 96 Tests Anmelden zum Anzeigen 11 bis 15 Tage
562,96 €
Details
Maus 0.117 ng/mL 0.312-20 ng/mL 96 Tests Anmelden zum Anzeigen 13 bis 16 Tage
859,10 €
Details
Ratte 0.78 ng/mL 3.12-200 ng/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 13 bis 17 Tage
772,39 €
Details
Human 0.056 ng/mL 0.312-20 ng/mL   96 Tests Anmelden zum Anzeigen 6 bis 8 Tage
716,57 €
Details
Huhn 1.875 ng/mL 3.125-200 ng/mL   96 Tests Anmelden zum Anzeigen 10 bis 13 Tage
666,67 €
Details
Meerschweinchen 0.375 ng/mL 0.625-40 ng/mL   96 Tests Anmelden zum Anzeigen 10 bis 13 Tage
666,67 €
Details
Affe 0.188 ng/mL 0.313-20 ng/mL   96 Tests Anmelden zum Anzeigen 10 bis 13 Tage
666,67 €
Details
Schwein 0.188 ng/mL 0.313-20 ng/mL   96 Tests Anmelden zum Anzeigen 10 bis 13 Tage
666,67 €
Details
Kaninchen 0.188 ng/mL 0.313-20 ng/mL   96 Tests Anmelden zum Anzeigen 10 bis 13 Tage
666,67 €
Details
Hund 0.1 ng/mL 1.0-25 ng/mL   96 Tests Anmelden zum Anzeigen 13 bis 17 Tage
673,47 €
Details

Am meisten referenzierte RUNX2 ELISA Kits

  1. Human RUNX2 ELISA Kit für Sandwich ELISA - ABIN416824 : Nagy, Eriksson, Yousry, Caidahl, Ingelsson, Hansson, Franco-Cereceda, Bäck: Valvular osteoclasts in calcification and aortic valve stenosis severity. in International journal of cardiology 2013 (PubMed)
    Zeige alle 2 Referenzen für 416824

Weitere ELISA Kits für RUNX2 Interaktionspartner

Zebrafish Runt-Related Transcription Factor 2 (RUNX2) Interaktionspartner

  1. Runx2 may have an evolutionarily conserved role in axis formation

Mouse (Murine) Runt-Related Transcription Factor 2 (RUNX2) Interaktionspartner

  1. SIRT1 (zeige SIRT1 ELISA Kits) interacts with and promotes the transactivation potential of RUNX2.

  2. ABL (zeige ABL1 ELISA Kits) potentiated the assembly and activation of the RUNX2-TAZ (zeige TAZ ELISA Kits) master transcription factor complex that is required for osteoblastogenesis, while antagonizing PPARgamma (zeige PPARG ELISA Kits)-mediated adipogenesis.

  3. urther investigation indicated that p205 (zeige GNB2L1 ELISA Kits) may disturb the formation of Runx2/Ids (zeige IDS ELISA Kits) complex and free more Runx2 to induce the differentiation process. Taken together, our findings demonstrated for the first time that p205 (zeige GNB2L1 ELISA Kits) functions as an activator in osteoblast differentiation.

  4. identified a novel genomic region in which DNA methylation (zeige HELLS ELISA Kits) status is related to Runx2 expression and detected demethylation of Runx2-DMR (zeige WDR20 ELISA Kits) during osteoblastic differentiation in mouse and dog.

  5. overexpression of Fam3c (zeige FAM3C ELISA Kits) caused reduction of Runx2 expression at both mRNA and protein levels. Fam3c (zeige FAM3C ELISA Kits) was localized in the cytoplasm and it was not secreted outside the cell during osteoblast differentiation and therefore, may function intracellularly. Furthermore, Fam3c (zeige FAM3C ELISA Kits) and TGF-beta1 (zeige TGFB1 ELISA Kits) were found to regulate each other reciprocally

  6. MAP kinase (zeige MAPK1 ELISA Kits)-dependent RUNX2 phosphorylation Is necessary for epigenetic modification of chromatin during osteoblast differentiation.

  7. These results suggested that endogenous PTH enhanced BMPR2 expression by a cAMP/PKA/CREB pathway in osteoblasts, and increased RUNX2 expression through transduction of the BMP/pSMAD1/5/8 signaling pathway

  8. suggest that RUNX2 and USAG-1 (zeige SOSTDC1 ELISA Kits) act in an antagonistic manner

  9. results provide evidence that WWP2 (zeige WWP2 ELISA Kits) serves as a positive regulator of osteogenesis by augmenting RUNX2 transactivation in a non-proteolytic mono-ubiquitination manner.

  10. Klotho (zeige KL ELISA Kits) gene deficiency promotes high-fat diet-induced fibrosis in aortic valves, likely through the AMPKalpha (zeige GRK4 ELISA Kits)-RUNX2 pathway.

Human Runt-Related Transcription Factor 2 (RUNX2) Interaktionspartner

  1. All the three novel RUNX2 mutations significantly reduced the transactivation activity of RUNX2 on osteocalcin (zeige BGLAP ELISA Kits) promoter.

  2. miR (zeige MLXIP ELISA Kits)-466-mediated attenuation of RUNX2 as a novel therapeutic approach to regulate prostate cancer growth, particularly metastasis to bone.

  3. miR (zeige MLXIP ELISA Kits)-203 has a crucial role in suppressing heterotopic ossification by directly targeting Runx2.

  4. mechanical load upregulates expression of Runx2 gene via potentiation of PC1 (zeige PCSK1 ELISA Kits)-JAK2 (zeige JAK2 ELISA Kits)/STAT3 (zeige STAT3 ELISA Kits) signaling axis, culminating to possibly control osteoblastic differentiation and ultimately bone formation.

  5. the Runx2 knockdown cells displayed activation of AMP-activated protein kinase (AMPKalpha (zeige GRK4 ELISA Kits)), the sensor of cellular metabolism. Importantly, the Runx2 knockdown in bone-derived cells resulted in increased sensitivity to both Erk1/2 (zeige MAPK1/3 ELISA Kits) inhibition and AMPKalpha (zeige GRK4 ELISA Kits) activation by PD184161 and metformin, respectively, despite increased IGF-1Rbeta and AMPKalpha (zeige GRK4 ELISA Kits) levels.

  6. RUNX2 mutation disturbs the modulatory effects of dental follicle cells and periodontal ligament cells on the differentiation of osteoclasts and osteoblasts, thereby interfering with bone remodelling. These effects may contribute in part to the pathological manifestations of retention of primary teeth and delayed eruption of permanent teeth in patients with cleidocranial dysplasia.

  7. RUNX2/P57 (zeige CDKN1C ELISA Kits) gene expression is strongly activated, in a process that is accompanied by enrichment of activating histone marks (H3K4me3, H3ac, and H3K27ac) at the P1 promoter region, to control osteogenic lineage commitment of umbilical cord derived mesenchymal stem cells.

  8. provide evidence to show that CBX4 may serve as a tumor suppressor in colorectal carcinoma by recruiting HDAC3 (zeige HDAC3 ELISA Kits) to the Runx2 promoter to impede Runx2 expression

  9. Suggest an adhesion-dependent mechanism of RUNX2 for the osteotropism and bone colonization of breast cancer cells and implicate RUNX2 and integrin alpha5 as potential molecular markers for the prediction of bone metastasis.

  10. our results defined a novel pathway in which dysregulation of the RUNX2/INHBA (zeige INHBA ELISA Kits) axis due to miR (zeige MLXIP ELISA Kits)-376c downregulation fosters lymph node metastasis in head and neck squamous cell carcinoma

Rabbit Runt-Related Transcription Factor 2 (RUNX2) Interaktionspartner

  1. The results suggest that gene therapy using Runx2-modi fi ed dental pulp stem cells was more effective during bone deposition and new bone formation in tibia Distraction osteogenesis.

  2. Runx2-modified adipose-derived stem cells promote tendon graft integration in anterior cruciate ligament reconstruction.

  3. The OPG (zeige TNFSF11 ELISA Kits) expression levels decreased while those of RANKL (zeige TNFSF11 ELISA Kits) and RUNX2 increased during orthodontic tooth movement, which suggested that they play a role in the osteogenesis process and the reconstruction of periodontal tissue.

Xenopus laevis Runt-Related Transcription Factor 2 (RUNX2) Interaktionspartner

  1. These data also indicate that MGP (zeige MGP ELISA Kits) is under dual regulation by runx2 through the use of various isoforms and context-dependent formation of transcriptional complexes.

Pig (Porcine) Runt-Related Transcription Factor 2 (RUNX2) Interaktionspartner

  1. Klotho (zeige KL ELISA Kits) gene deficiency promotes high-fat diet-induced fibrosis in aortic valves, likely through the AMPKalpha (zeige GRK4 ELISA Kits)-RUNX2 pathway.

RUNX2 Antigen-Profil

Beschreibung des Gens

This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing.

Genbezeichner und Symbole assoziert mit RUNX2

  • runt-related transcription factor 2a (runx2a) Antikörper
  • transcription factor Cbfa1 (runx2) Antikörper
  • runt-related transcription factor 2 (RUNX2) Antikörper
  • runt-related transcription factor 2 (runx2) Antikörper
  • runt related transcription factor 2 (Runx2) Antikörper
  • runt-related transcription factor 2 (Runx2) Antikörper
  • runt-related transcription factor 2 (LOC100339156) Antikörper
  • runt-related transcription factor 2-like (LOC100737965) Antikörper
  • AML3 Antikörper
  • Cbf Antikörper
  • CBF-alpha-1 Antikörper
  • Cbfa-1 Antikörper
  • CBFA1 Antikörper
  • CCD Antikörper
  • CCD1 Antikörper
  • CLCD Antikörper
  • LS3 Antikörper
  • OSF-2 Antikörper
  • OSF2 Antikörper
  • PEA2aA Antikörper
  • Pebp2a1 Antikörper
  • pebp2a2 Antikörper
  • PEBP2aA Antikörper
  • pebp2aa1 Antikörper
  • Pebpa2a Antikörper
  • RUNX2 Antikörper

Bezeichner auf Proteinebene für RUNX2

runt-related transcription factor 2 , transcription factor Runx2a , transcription factor Cbfa1 , runt-related transcription factor 2-like , AKV core binding factor , CBF-alpha-1 , PEA2-alpha A , PEBP2 alpha A , SL3-3 enhancer factor 1 alpha A subunit , acute myeloid leukemia 3 protein , core binding factor alpha 1 , osteoblast-specific transcription factor 2 , polyomavirus enhancer-binding protein 2 alpha A subunit , runt domain, alpha subunit 1 , PEBP2-alpha A , SL3/AKV core-binding factor alpha A subunit , core-binding factor, runt domain, alpha subunit 1 , oncogene AML-3 , runt-related factor 2 , core-binding factor subunit alpha-1 , runt related transcription factor 2 , Runx2 spliced isoform , runt-related transcription factor 2 type I , runt-related transcription factor 2 type II , core binding factor alpha 1 subunit

GENE ID SPEZIES
405784 Danio rerio
445986 Takifugu rubripes
449531 Canis lupus familiaris
472017 Pan troglodytes
703331 Macaca mulatta
100080409 Ornithorhynchus anatinus
100189546 Xenopus (Silurana) tropicalis
100222668 Taeniopygia guttata
100406564 Callithrix jacchus
100453201 Pongo abelii
100549663 Meleagris gallopavo
100555776 Anolis carolinensis
100619969 Monodelphis domestica
12393 Mus musculus
860 Homo sapiens
474923 Canis lupus familiaris
536911 Bos taurus
100008943 Oryctolagus cuniculus
367218 Rattus norvegicus
100037059 Xenopus laevis
373919 Gallus gallus
100734175 Cavia porcellus
100033890 Equus caballus
100155806 Sus scrofa
100339156 Oryctolagus cuniculus
100861217 Capra hircus
101115489 Ovis aries
100737965 Sus scrofa
Ausgewählte Anbieter für RUNX2 (RUNX2) ELISA Kits
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