anti-Runt-Related Transcription Factor 2 (RUNX2) Antikörper

RUNX2 is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. Zusätzlich bieten wir Ihnen RUNX2 Kits (49) und RUNX2 Proteine (12) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
RUNX2 860 Q13950
RUNX2 12393 Q08775
RUNX2 367218  
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Top anti-RUNX2 Antikörper auf antikoerper-online.de

Showing 10 out of 240 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-RUNX2 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>721_B cell lysate WB Suggested Anti-RUNX2 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500 <br /> Positive Control:.21_B cell lysate <br /> RUNX2 is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-RUNX2 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:2500<br><b>Positive Control: </b>HepG2 cell lysate Sample Type: Lane 1:241 µg mouse mesenchymal stem cell lysate <br />Primary Antibody Dilution: 1:0000<br />Secondary Antibody: Anti-rabbit-HRP <br />Secondary Antibody Dilution: 1:00,000 Color/Signal Descriptions: RUNX2 <br /> Gene Name: Anonymous <br /><br />Submitted by: 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-RUNX2 Antibody Titration: </b>1.25ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>Jurkat cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$229.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-RUNX2 Antibody Titration: </b>1.25ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$229.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-Runx2 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>Rat Liver WB Suggested Anti-Runx2 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500 <br /> Positive Control: Rat Liver 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert WB Observed bind size: 62KD Anti-RUNX2 Picoband antibody,  All lanes: Anti RUNX2  at 0.5ug/ml WB: Recombinant Human RUNX2 Protein 0.5ng Predicted bind size: 50KD Observed bind size: 50KD 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$240.00
Details
Human Kaninchen Unkonjugiert EIA 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Huhn Kaninchen Unkonjugiert IHC, WB Immunohistochemical analysis of RUNX2 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of RUNX2 expression in Saos2 (A), HepG2 (B), Jurkat (C) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert WB Anti-RUNX2 antibody, Western blotting Lane 1: Rat Thymus Tissue Lysate Lane 2: Rat Testis Tissue Lysate 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$200.00
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of RUNX2 expression in K562 (A), Hela (B) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details

RUNX2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-RUNX2 Antikörper

  1. Human Polyclonal RUNX2 Primary Antibody für DB - ABIN389942 : McNamara, Sjöström, Burgess, Kim, Liu, Gordonov, Moghe, Meek, Oreffo, Su, Dalby: Skeletal stem cell physiology on functionally distinct titania nanotopographies. in Biomaterials 2011 (PubMed)
    Show all 8 Pubmed References

  2. Human Polyclonal RUNX2 Primary Antibody für WB - ABIN3043708 : Li, Chen, Peng, Zhou, Fang: Pulsed electromagnetic fields protect the balance between adipogenesis and osteogenesis on steroid-induced osteonecrosis of femoral head at the pre-collapse stage in rats. in Bioelectromagnetics 2014 (PubMed)
    Show all 6 Pubmed References

  3. Human Polyclonal RUNX2 Primary Antibody für WB - ABIN3043428 : Wang, Mu, Fan, Yu, Yan, Lei, Tang, Wang, Zheng, Yu, Zhang: Insulin-like growth factor 1 can promote the osteogenic differentiation and osteogenesis of stem cells from apical papilla. in Stem cell research 2012 (PubMed)
    Show all 6 Pubmed References

  4. Human Polyclonal RUNX2 Primary Antibody für EMSA - ABIN3434043 : Huang, Xie, Konaka, Sodek, Zhau, Chung: Human osteocalcin and bone sialoprotein mediating osteomimicry of prostate cancer cells: role of cAMP-dependent protein kinase A signaling pathway. in Cancer research 2005 (PubMed)
    Show all 5 Pubmed References

  5. Human Monoclonal RUNX2 Primary Antibody für IF, IHC (p) - ABIN514045 : Wang, Li, Li, Yang, Sasaki, Wang, Zhou, Araki, Mezawa, Takai, Ogata: Effects of inorganic polyphosphate on bone sialoprotein gene expression. in Gene 2010 (PubMed)
    Show all 5 Pubmed References

  6. Human Polyclonal RUNX2 Primary Antibody für ICC, IF - ABIN4351437 : Mao, Shin, Mooney: Effects of substrate stiffness and cell-cell contact on mesenchymal stem cell differentiation. in Biomaterials 2016 (PubMed)
    Show all 4 Pubmed References

  7. Human Polyclonal RUNX2 Primary Antibody für ICC, IF - ABIN4351441 : Martínez-Abadías, Holmes, Pankratz, Wang, Zhou, Jabs, Richtsmeier: From shape to cells: mouse models reveal mechanisms altering palate development in Apert syndrome. in Disease models & mechanisms 2013 (PubMed)
    Show all 3 Pubmed References

  8. Human Monoclonal RUNX2 Primary Antibody für IF, IHC (p) - ABIN560185 : Sase, Suzuki, Miura, Shiiba, Sato, Nakamura, Takagi, Onodera, Miki, Watanabe, Ishida, Ohnuma, Sasaki, Sato, Karasawa, Shibata, Unno, Sasaki, Sasano: Runt-related transcription factor 2 in human colon carcinoma: a potent prognostic factor associated with estrogen receptor. in International journal of cancer. Journal international du cancer 2012 (PubMed)
    Show all 2 Pubmed References

  9. Cow (Bovine) Polyclonal RUNX2 Primary Antibody für WB - ABIN2780588 : Lee, Lee, Ryoo, Park, Park, Bae, Cho, Park: The odontogenic ameloblast-associated protein (ODAM) cooperates with RUNX2 and modulates enamel mineralization via regulation of MMP-20. in Journal of cellular biochemistry 2010 (PubMed)
    Show all 2 Pubmed References

  10. Human Polyclonal RUNX2 Primary Antibody für ICC, IF - ABIN4351459 : Mao, Shin, Utech, Wang, Uzun, Li, Cooper, Hu, Zhang, Weitz, Mooney: Deterministic encapsulation of single cells in thin tunable microgels for niche modelling and therapeutic delivery. in Nature materials 2016 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen RUNX2 Interaktionspartner

Human Runt-Related Transcription Factor 2 (RUNX2) Interaktionspartner

  1. these studies define a novel fibrinogen-alpha9beta1-SMAD1 (zeige GARS Antikörper)/5/8-RUNX2 signaling axis can efficiently induce osteogenic differentiation from human embryonic stem cells and induced pluripotent stem cells.

  2. Data show that BRD4 (zeige BRD4 Antikörper) controls RUNX2 by binding to the enhancers (ENHs) and each RUNX2 ENH (zeige PDLIM5 Antikörper) is potentially controlled by a distinct set of TFs and c-JUN (zeige JUN Antikörper) as the principal pivot of this regulatory platform.

  3. TGF-beta1 (zeige TGFB1 Antikörper) stimulates the phosphorylation of Runx2 at three serine amino acids, and this event is required for MMP-13 (zeige MMP13 Antikörper) expression in osteoblastic cells.

  4. TP(thymidine phosphorylase (zeige TYMP Antikörper) ) curbed the expression of three proteins-IRF8 (zeige IRF8 Antikörper), RUNX2, and osterix (zeige SP7 Antikörper). This downregulation was epigenetically driven: High levels of 2DDR, a product of TP secreted by myeloma cells, activated PI3K (zeige PIK3CA Antikörper)/AKT (zeige AKT1 Antikörper) signaling and increased the methyltransferase DNMT3A's expression

  5. Overexpression of miR (zeige MLXIP Antikörper)-196b suppressed cell viability, migration, invasion, and induced apoptosis as well as inhibited TGF-beta (zeige TGFB1 Antikörper) induced epithelial mesenchymal transition process in A549 cells. In addition, Runx2 was a putative target of miR (zeige MLXIP Antikörper)-196b, and Runx2 silence remarkably increased cell apoptosis and abolished the promotive effects of miR (zeige MLXIP Antikörper)-196b suppression on cell viability, migration and invasion.

  6. This study showed that si-Grem2 (zeige GREM2 Antikörper) increased the BMP-2 (zeige BMP2 Antikörper)-induced osteogenic differentiation of hBMSCs via the BMP-2 (zeige BMP2 Antikörper)/Smad (zeige SMAD1 Antikörper)/Runx2 pathway.

  7. Runx2 promotes autophagy in metastatic breast cancer cells by increasing acetylation of alpha-tubulin (zeige TUBA4A Antikörper) sub-units of microtubules.

  8. Mutation in the RUNX2 gene is associated with acute myeloid leukemia (zeige BCL11A Antikörper) patients with lympho-myeloid clonal hematopoiesis.

  9. present observations strongly suggest that RUNX2/mutant p53 (zeige TP53 Antikörper)/TAp63-regulatory axis is one of the key determinants of SAHA sensitivity of p53 (zeige TP53 Antikörper)-mutated pancreatic cancer cells

  10. All the three novel RUNX2 mutations significantly reduced the transactivation activity of RUNX2 on osteocalcin (zeige BGLAP Antikörper) promoter.

Zebrafish Runt-Related Transcription Factor 2 (RUNX2) Interaktionspartner

  1. Runx2 may have an evolutionarily conserved role in axis formation

Mouse (Murine) Runt-Related Transcription Factor 2 (RUNX2) Interaktionspartner

  1. Nearly half of all DNase (zeige DNASE2 Antikörper) hypersensitivity sites (both constitutive and dynamic) overlap binding events of the bone-essential RUNX2 and/or the chromatin-related CTCF (zeige CTCF Antikörper) transcription factors.

  2. The findings suggest that the absence of uPA (zeige PLAU Antikörper) correlates with increased levels of Runx transcriptional regulators in a way that promotes inflammation-associated carcinogenesis.

  3. Fam50a (zeige FAM50A Antikörper) might be a new positive regulator of ameloblast differentiation, increasing binding affinity of Runx2 to Ambn (zeige AMBN Antikörper) promoter by physically interacting with Runx2.

  4. Knockdown of MACF1 (zeige MACF1 Antikörper) in osteoblastic cells inhibits osteoblast differentiation through suppressing the beta-catenin (zeige CTNNB1 Antikörper)/TCF1 (zeige HNF1A Antikörper)-Runx2 axis.

  5. These results suggest that Dietary methionine restriction (MR) alters bone remodeling and apposition. In MR mice, miR (zeige MLXIP Antikörper)-31 in plasma and liver, and miR (zeige MLXIP Antikörper)-133a, miR (zeige MLXIP Antikörper)-335-5p, and miR (zeige MLXIP Antikörper)-204 in the bone marrow was elevated. These miRNAs were shown previously to target and regulate Osterix (zeige SP7 Antikörper) and RUNX2 in bone, which could inhibit osteoblast differentiation and function.

  6. SIRT1 (zeige SIRT1 Antikörper) interacts with and promotes the transactivation potential of RUNX2.

  7. ABL (zeige ABL1 Antikörper) potentiated the assembly and activation of the RUNX2-TAZ (zeige TAZ Antikörper) master transcription factor complex that is required for osteoblastogenesis, while antagonizing PPARgamma (zeige PPARG Antikörper)-mediated adipogenesis.

  8. urther investigation indicated that p205 (zeige GNB2L1 Antikörper) may disturb the formation of Runx2/Ids (zeige IDS Antikörper) complex and free more Runx2 to induce the differentiation process. Taken together, our findings demonstrated for the first time that p205 (zeige GNB2L1 Antikörper) functions as an activator in osteoblast differentiation.

  9. identified a novel genomic region in which DNA methylation (zeige HELLS Antikörper) status is related to Runx2 expression and detected demethylation of Runx2-DMR (zeige WDR20 Antikörper) during osteoblastic differentiation in mouse and dog.

  10. overexpression of Fam3c (zeige FAM3C Antikörper) caused reduction of Runx2 expression at both mRNA and protein levels. Fam3c (zeige FAM3C Antikörper) was localized in the cytoplasm and it was not secreted outside the cell during osteoblast differentiation and therefore, may function intracellularly. Furthermore, Fam3c (zeige FAM3C Antikörper) and TGF-beta1 (zeige TGFB1 Antikörper) were found to regulate each other reciprocally

Rabbit Runt-Related Transcription Factor 2 (RUNX2) Interaktionspartner

  1. The results suggest that gene therapy using Runx2-modi fi ed dental pulp stem cells was more effective during bone deposition and new bone formation in tibia Distraction osteogenesis.

  2. Runx2-modified adipose-derived stem cells promote tendon graft integration in anterior cruciate ligament reconstruction.

  3. The OPG (zeige TNFSF11 Antikörper) expression levels decreased while those of RANKL (zeige TNFSF11 Antikörper) and RUNX2 increased during orthodontic tooth movement, which suggested that they play a role in the osteogenesis process and the reconstruction of periodontal tissue.

Xenopus laevis Runt-Related Transcription Factor 2 (RUNX2) Interaktionspartner

  1. These data also indicate that MGP (zeige MGP Antikörper) is under dual regulation by runx2 through the use of various isoforms and context-dependent formation of transcriptional complexes.

Pig (Porcine) Runt-Related Transcription Factor 2 (RUNX2) Interaktionspartner

  1. Klotho (zeige KL Antikörper) gene deficiency promotes high-fat diet-induced fibrosis in aortic valves, likely through the AMPKalpha (zeige GRK4 Antikörper)-RUNX2 pathway.

RUNX2 Antigen-Profil

Protein Überblick

This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing.

Genbezeichner und Symbole assoziert mit RUNX2

  • runt related transcription factor 2 (RUNX2) Antikörper
  • runt-related transcription factor 2a (runx2a) Antikörper
  • runt related transcription factor 2 (Runx2) Antikörper
  • runt-related transcription factor 2 (Runx2) Antikörper
  • runt related transcription factor 2 (runx2) Antikörper
  • uncharacterized LOC449531 (LOC449531) Antikörper
  • runt-related transcription factor 2 (LOC703331) Antikörper
  • runt-related transcription factor 2 (LOC100549663) Antikörper
  • runt related transcription factor 2 L homeolog (runx2.L) Antikörper
  • runt-related transcription factor 2 (RUNX2) Antikörper
  • aml3 Antikörper
  • Cbf Antikörper
  • CBF-alpha-1 Antikörper
  • Cbfa-1 Antikörper
  • cbfa1 Antikörper
  • ccd Antikörper
  • ccd1 Antikörper
  • CLCD Antikörper
  • LS3 Antikörper
  • OSF-2 Antikörper
  • osf2 Antikörper
  • pea2aa Antikörper
  • pebp2a1 Antikörper
  • pebp2a2 Antikörper
  • pebp2aa Antikörper
  • pebp2aa1 Antikörper
  • Pebpa2a Antikörper
  • RUNX2 Antikörper

Bezeichner auf Proteinebene für RUNX2

PEA2-alpha A , PEBP2-alpha A , SL3-3 enhancer factor 1 alpha A subunit , SL3/AKV core-binding factor alpha A subunit , acute myeloid leukemia 3 protein , core-binding factor, runt domain, alpha subunit 1 , oncogene AML-3 , osteoblast-specific transcription factor 2 , polyomavirus enhancer-binding protein 2 alpha A subunit , runt-related transcription factor 2 , transcription factor Runx2a , AKV core binding factor , CBF-alpha-1 , PEBP2 alpha A , core binding factor alpha 1 , runt domain, alpha subunit 1 , core-binding factor subunit alpha-1 , runt related transcription factor 2 , transcription factor Cbfa1 , runt-related factor 2 , core binding factor alpha 1 subunit , runt-related transcription factor 2-like , Runx2 spliced isoform , runt-related transcription factor 2 type I , runt-related transcription factor 2 type II

GENE ID SPEZIES
860 Homo sapiens
405784 Danio rerio
12393 Mus musculus
367218 Rattus norvegicus
373919 Gallus gallus
445986 Takifugu rubripes
449531 Canis lupus familiaris
472017 Pan troglodytes
703331 Macaca mulatta
100008943 Oryctolagus cuniculus
100033890 Equus caballus
100080409 Ornithorhynchus anatinus
100189546 Xenopus (Silurana) tropicalis
100222668 Taeniopygia guttata
100406564 Callithrix jacchus
100453201 Pongo abelii
100549663 Meleagris gallopavo
100555776 Anolis carolinensis
100619969 Monodelphis domestica
100037059 Xenopus laevis
536911 Bos taurus
100737965 Sus scrofa
474923 Canis lupus familiaris
100734175 Cavia porcellus
100861217 Capra hircus
101115489 Ovis aries
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