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anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) Antikörper

RUNX1T1 encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. Zusätzlich bieten wir Ihnen RUNX1T1 Proteine (6) und RUNX1T1 Kits (2) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
RUNX1T1 862 Q06455
RUNX1T1 12395 Q61909
RUNX1T1 362489  
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Top anti-RUNX1T1 Antikörper auf antikoerper-online.de

Showing 10 out of 40 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Huhn Kaninchen Unkonjugiert WB WB Suggested Anti-RUNX1T1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: 293T cell lysate 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Huhn Kaninchen Unkonjugiert WB WB Suggested Anti-RUNX1T1 Antibody Titration: 1.25ug/mlPositive Control: HepG2 cell lysate 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
288,68 €
Details
Xenopus laevis Kaninchen Unkonjugiert WB Human 721_B; Host: Rabbit. Target Name: WT1 . Sample Tissue: 721_B . Antibody Dilution: 1.0ug/ml. RUNX1T1 is supported by BioGPS gene expression data to be expressed in 721_B.; RUNX1T1 antibody - middle region in Human 721_B cells using Western Blot Human HepG2; WB Suggested Anti-RUNX1T1 Antibody Titration: 1.25ug/ml. Positive Control: HepG2 cell lysate. There is BioGPS gene expression data showing that RUNX1T1 is expressed in HepG2.; RUNX1T1 antibody - middle region in Human HepG2 cells using Western Blot 0.1 mg Anmelden zum Anzeigen 8 bis 10 Tage
357,50 €
Details
Human Maus Unkonjugiert IF, WB Anti-RUNX1T1 mouse monoclonal antibody (ABIN2455775) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY RUNX1T1 (RC222426). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RUNX1T1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-RUNX1T1. 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
418,10 €
Details
Fledermaus Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 11 bis 14 Tage
583,17 €
Details
Human Maus Unkonjugiert ELISA, WB Western Blot detection against Immunogen (38.21 KDa) . 50 μL Anmelden zum Anzeigen 8 bis 9 Tage
241,60 €
Details
Hund Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
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Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
Details
Human Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Maus Unkonjugiert WB Western Blot analysis of RUNX1T1 expression in transfected 293T cell line by RUNX1T1 monoclonal antibody (M01), clone 5A12. Lane 1: RUNX1T1 transfected lysate(67.566 KDa). Lane 2: Non-transfected lysate. Detection limit for recombinant GST tagged RUNX1T1 is approximately 0.3 ng/mL as a capture antibody. 0.1 mg Anmelden zum Anzeigen 12 bis 16 Tage
454,76 €
Details

RUNX1T1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
Human , , , ,
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Mouse (Murine) ,


Rat (Rattus) ,


Am meisten referenzierte anti-RUNX1T1 Antikörper

  1. Human Polyclonal RUNX1T1 Primary Antibody für ELISA, WB - ABIN560189 : Abdelhaleem: RNA helicases: regulators of differentiation. in Clinical biochemistry 2005 (PubMed)
    Zeige alle 4 Referenzen für ABIN560189

  2. Chicken Polyclonal RUNX1T1 Primary Antibody für WB - ABIN2787562 : Salat, Liefke, Wiedenmann, Borggrefe, Oswald: ETO, but not leukemogenic fusion protein AML1/ETO, augments RBP-Jkappa/SHARP-mediated repression of notch target genes. in Molecular and cellular biology 2008 (PubMed)

  3. Xenopus laevis Polyclonal RUNX1T1 Primary Antibody für WB - ABIN1108915 : Lausen, Cho, Liu, Werner: The nuclear receptor co-repressor (N-CoR) utilizes repression domains I and III for interaction and co-repression with ETO. in The Journal of biological chemistry 2004 (PubMed)

Weitere Antikörper gegen RUNX1T1 Interaktionspartner

Human Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) Interaktionspartner

  1. the AML1 (zeige RUNX1 Antikörper)-ETO fusion protein increases the expression of SIRT1 (zeige SIRT1 Antikörper), possibly by binding to the promoter region of SIRT1 (zeige SIRT1 Antikörper) to activate its transcription in t(8;21) AML (zeige RUNX1 Antikörper).

  2. A feedback circuitry involving miR (zeige MLXIP Antikörper)-9-1 and RUNX1 (zeige RUNX1 Antikörper)-RUNX1T1.

  3. The role of RUNX1T1 in t(8;21) acute myeloid leukemia (zeige BCL11A Antikörper) and miRNA expression regulation

  4. Our data revealed a novel role for RUNX1T1 as a tumor-suppressor gene in colorectal cancer through modulation of multiple cellular pathways affecting the cell cycle, DNA damage, DNA replication, estrogen signaling, and drug resistance

  5. Exon splicing patterns in the human RUNX1 (zeige RUNX1 Antikörper)-RUNX1T1 fusion gene present in acute myeloid leukemia (zeige BCL11A Antikörper) patients have been decoded.

  6. Data suggest that biosynthesis and folding of leukemogenic fusion oncoprotein AML1 (zeige RUNX1 Antikörper)-ETO/RUNX1 (zeige RUNX1 Antikörper)-RUNX1T1 is facilitated by interaction with the chaperonin (zeige HSPD1 Antikörper) TRiC/CCT1/TCP1 and HSP70 (heat shock protein 70 (zeige HSP70 Antikörper)).

  7. AML1/ETO transactivates gene expression through recruiting AP-1 to the AML1/ETO-AML1 complex.

  8. A substantial fraction of AML1 (zeige RUNX1 Antikörper)-ETO/p300 (zeige EP300 Antikörper) co-localization occurs near TSSs in promoter regions associated with transcriptionally active loci.

  9. minimal residual disease determined by RUNX1 (zeige RUNX1 Antikörper)/RUNX1T1 transcript levels could identify allogeneic hematopoietic stem cell transplantation t(8;21) (q22;q22) acute myeloid leukemia (zeige BCL11A Antikörper) patients who are at high risk for relapse, together with c-KIT (zeige KIT Antikörper) mutations

  10. identify a high-frequency mutation in t(8;21)/RUNX1 (zeige RUNX1 Antikörper)-RUNX1T1 acute myekoid leukemia (AML (zeige RUNX1 Antikörper)) and identify the need for future studies to investigate the clinical and biological relevance of ASXL2 (zeige ASXL2 Antikörper) mutations in this unique subset of AML (zeige RUNX1 Antikörper)

Mouse (Murine) Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) Interaktionspartner

  1. Data show that RUNX1 (zeige RUNX1 Antikörper)-ETO;c-Kit (zeige KIT Antikörper)(T417IDelta418-419) coexpression promoted exclusively acute myeloid leukemia (zeige BCL11A Antikörper) (AML (zeige RUNX1 Antikörper)) in a fraction (51%) of reconstituted mice.

  2. Self-renewal induced by AML1 (zeige RUNX1 Antikörper)/ETO in primary murine progenitors was inhibited when Aes (zeige AES Antikörper) was decreased or absent.

  3. AML1 (zeige RUNX1 Antikörper)-ETO synergizes with an ICSBP (zeige IRF8 Antikörper) deficiency to induce myeloblastic transformation in the bone marrow, reminiscent of acute myelogenous leukemia

  4. molecular role for ETO in normal physiology as an inhibitor of C/EBPbeta (zeige CEBPB Antikörper) and a novel regulator of early adipogenesis

  5. the loss of the molecular events of AML1 (zeige RUNX1 Antikörper)-ETO C-terminal NCoR (zeige NCOR1 Antikörper)/SMRT (zeige NCOR2 Antikörper)-interacting domain transforms AML1 (zeige RUNX1 Antikörper)-ETO into a potent leukemogenic protein

  6. p15(Ink4b (zeige CDKN2B Antikörper)) loss must be accompanied by additional oncogenic changes for RUNX1 (zeige RUNX1 Antikörper)-ETO-associated AML (zeige RUNX1 Antikörper) to develop

  7. AML1 DNA-binding domain and the ETO NHR2-dimerization domain, but not the ETO NHR1 domain, are critical for the induction of acute myeloid leukemia by AML1-ETO9a

  8. the eTAFH-E protein interaction appears to contribute relatively little to the activity of AML1 (zeige RUNX1 Antikörper)-ETO

RUNX1T1 Antigen-Profil

Protein Überblick

This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(8\;21)(q22\;q22) translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Alternative splicing results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit RUNX1T1

  • runt-related transcription factor 1; translocated to, 1 (cyclin D-related) (runx1t1) Antikörper
  • runt-related transcription factor 1; translocated to, 1 (cyclin D-related) (RUNX1T1) Antikörper
  • runt-related transcription factor 1; translocated to, 1 (cyclin D-related) (Runx1t1) Antikörper
  • AML1T1 Antikörper
  • Cbfa2t1 Antikörper
  • Cbfa2t1h Antikörper
  • CDR Antikörper
  • ETO Antikörper
  • MTG8 Antikörper
  • si:ch211-232j17.1 Antikörper
  • wu:fi14b07 Antikörper
  • zgc:154044 Antikörper
  • ZMYND2 Antikörper

Bezeichner auf Proteinebene für RUNX1T1

protein CBFA2T1 , MTG8 , MTG8/ETOb , expressed during postmitotic spinal neurons, most likely in motorneurons , acute myelogenous leukemia 1 translocation 1, cyclin-D related , core-binding factor, runt domain, alpha subunit 2; translocated to, 1; cyclin D-related , eight twenty one protein , myeloid translocation gene on 8q22 , zinc finger MYND domain-containing protein 2 , CBFA2T1 identified gene homolog , acute myelogenous leukemia 1 translocation 1 protein , core-binding factor, runt domain, alpha subunit 2 , cyclin D-related , translocated to, 1

GENE ID SPEZIES
767809 Danio rerio
733153 Xenopus laevis
395503 Gallus gallus
862 Homo sapiens
487044 Canis lupus familiaris
12395 Mus musculus
362489 Rattus norvegicus
100155449 Sus scrofa
Ausgewählte Anbieter für anti-RUNX1T1 (RUNX1T1) Antikörper
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