anti-Roundabout, Axon Guidance Receptor, Homolog 3 (Drosophila) (ROBO3) Antikörper

ROBO3 is a member of the Roundabout (ROBO) gene family that controls neurite outgrowth, growth cone guidance, and axon fasciculation. Zusätzlich bieten wir Ihnen ROBO3 Proteine (8) und ROBO3 Kits (2) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
ROBO3 64221 Q96MS0
ROBO3 315564  
ROBO3 19649  
Direkt bei antikoerper-online bestellen
  • +49 (0)241 95 163 153
  • +49 (0)241 95 163 155
  • Online bestellen
  • orders@antikoerper-online.de

Top anti-ROBO3 Antikörper auf antikoerper-online.de

Showing 10 out of 88 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Ziege Unkonjugiert ELISA, WB ABIN190793 (0.5µg/ml) staining of Human Brain (Cerebellum) lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 3 bis 4 Tage
349,82 €
Details
Maus Ziege Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 3 bis 4 Tage
249,70 €
Details
Human Ziege Unkonjugiert ELISA, WB Western Blot: Robo3 Antibody [NBP1-06071] - Analysis of Robo3 (internal) using this antibody at 0.5 ug/ml in Human Brain (Cerebellum) lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Anmelden zum Anzeigen 2 bis 4 Tage
311,00 €
Details
Human Ziege Unkonjugiert EIA, WB   0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
357,50 €
Details
Hund Ziege Unkonjugiert EIA, FACS   0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
385,00 €
Details
Human Ziege Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 11 bis 14 Tage
722,86 €
Details
Human Ziege Unkonjugiert ELISA, WB 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
505,48 €
Details
Maus Ziege Unkonjugiert ELISA   0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
472,74 €
Details
Human Ziege Unkonjugiert FACS, ELISA, WB   0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
505,48 €
Details
Maus Ziege Unkonjugiert ELISA   100 μg Anmelden zum Anzeigen 11 bis 14 Tage
600,64 €
Details

ROBO3 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Human , , , ,
, ,
,
, , , , , , , , , , , , , , , ,
Rat (Rattus) , , ,
,

, , , , , , , , , , , , , ,
Mouse (Murine) , , ,
,

, , , , , , , , , , , , , , , ,

Am meisten referenzierte anti-ROBO3 Antikörper

  1. Human Polyclonal ROBO3 Primary Antibody für ELISA, WB - ABIN190793 : Kato, Takeuchi, Sato, Yoneyama, Yamamoto, Matsui, Uematsu, Jung, Kawai, Ishii, Yamaguchi, Otsu, Tsujimura, Koh, Reis e Sousa, Matsuura, Fujita, Akira: Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses. in Nature 2006 (PubMed)
    Zeige alle 2 Referenzen für 190793

  2. Dog (Canine) Polyclonal ROBO3 Primary Antibody für EIA, FACS - ABIN783922 : Denk, Kaufmann, Stark, Schedel, Lowin, Schubert, Bosserhoff: Slit3 inhibits Robo3-induced invasion of synovial fibroblasts in rheumatoid arthritis. in Arthritis research & therapy 2010 (PubMed)

Weitere Antikörper gegen ROBO3 Interaktionspartner

Mouse (Murine) Roundabout, Axon Guidance Receptor, Homolog 3 (Drosophila) (ROBO3) Interaktionspartner

  1. This study show that this commissural neuron population includes spinal inhibitory neurons and sensory nociceptors and show that this population depends on Robo/Slit signaling yet crosses the dorsal midline in a Robo3-independent manner.

  2. These findings identify NELL2 (zeige NELL2 Antikörper) as an axon guidance cue and establish Robo3 as a multifunctional regulator of pathfinding that simultaneously mediates NELL2 (zeige NELL2 Antikörper) repulsion, inhibits Slit repulsion, and facilitates Netrin attraction to achieve a common guidance purpose.

  3. results suggest that Robo3 evolution was key to sculpting the mammalian brain by converting a receptor for Slit repulsion into one that both silences Slit repulsion and potentiates Netrin attraction

  4. this study demonistrated that Robo3-driven axon midline crossing conditions functional maturation of a large commissural synapse.

  5. Rerouting climbing fibers to an ipsilateral projection reversed complex-spike modulation. Ptf1a (zeige PTF1A Antikörper)::cre;Robo3(lox/lox (zeige LOX Antikörper)) mice showed severe ataxia (zeige USP14 Antikörper) indicating the impact of climbing fi ber input on reciprocity of Purkinje cell fi ring during motor coordination.

  6. Posttranscriptional regulation of Robo3 mediated by Musashi-1 (zeige MSI1 Antikörper) controls midline crossing of precerebellar neurons.

  7. Pax-2 (zeige PAX2 Antikörper)/RB binding reverses repression of Rig-1 protein.

  8. The Slit receptors Robo2 (zeige ROBO2 Antikörper) and Robo3/Rig-1 are expressed in the subventricular zone and the rostral migratory stream and Slit1 (zeige SLIT1 Antikörper) and Slit2 (zeige SLIT2 Antikörper) are present in the adult septum and are responsible for both the septum and the CP repulsive activity in vitro

  9. Expression of Rig-1 protein by commissural axons is inversely correlated with Slit sensitivity. Removal of Rig-1 results in a total failure of commissural axons to cross.

  10. two functionally antagonistic isoforms of Robo3 with distinct carboxy termini arising from alternative splicing have been found

Human Roundabout, Axon Guidance Receptor, Homolog 3 (Drosophila) (ROBO3) Interaktionspartner

  1. confirmed that ROBO3 increases with clinical grade and miR (zeige MLXIP Antikörper)-383 expression is inversely correlated to that of ROBO3

  2. human AKAP79-anchored PKC selectively phosphorylates the Robo3.1 receptor subtype on serine 1330

  3. We report the case of a 10-month-old girl with cross-fixation and inability to abduct who was genetically proven to have horizontal gaze palsy with progressive scoliosis (recessive ROBO3 mutations).

  4. Robo3.1A may prevent the Slit responsiveness by recruiting Robo1 (zeige ROBO1 Antikörper)/2 into a late endosome- and lysosome-dependent degradation pathway.

  5. The novel ROBO3 mutation in this family may be among the most deleterious

  6. This patient had clinical and neuroimaging characteristics considered pathognomonic of horizontal gaze palsy and progressive scoliosis and yet did not have ROBO3 mutations

  7. Three novel ROBO3 mutations have been identified in consanguineous patients with horizontal gaze palsy and progressive scoliosis.

  8. RIG-I (zeige DDX58 Antikörper) or melanoma differentiation-associated gene (MDA)5 (zeige IFIH1 Antikörper) signaling through mitochondrial antiviral signaling protein MAVS (zeige MAVS Antikörper) is required for activation of interferon (zeige IFNA Antikörper) (IFN)-beta (zeige IFNB1 Antikörper) production by rotavirus-infected intestinal epithelial cells.

  9. Slit3 (zeige SLIT1 Antikörper) inhibits Robo3-induced invasion of synovial fibroblasts in rheumatoid arthritis.

  10. mutations in the ROBO3 gene, which shares homology with roundabout (zeige ROBO1 Antikörper) genes important in axon guidance in developing Drosophila, zebrafish, and mouse.

ROBO3 Antigen-Profil

Protein Überblick

This gene is a member of the Roundabout (ROBO) gene family that controls neurite outgrowth, growth cone guidance, and axon fasciculation. ROBO proteins are a subfamily of the immunoglobulin transmembrane receptor superfamily. SLIT proteins 1-3, a family of secreted chemorepellants, are ligands for ROBO proteins and SLIT/ROBO interactions regulate myogenesis, leukocyte migration, kidney morphogenesis, angiogenesis, and vasculogenesis in addition to neurogenesis. This gene, ROBO3, has a putative extracellular domain with five immunoglobulin (Ig)-like loops and three fibronectin (Fn) type III motifs, a transmembrane segment, and a cytoplasmic tail with three conserved signaling motifs: CC0, CC2, and CC3 (CC for conserved cytoplasmic). Unlike other ROBO family members, ROBO3 lacks motif CC1. The ROBO3 gene regulates axonal navigation at the ventral midline of the neural tube. In mouse, loss of Robo3 results in a complete failure of commissural axons to cross the midline throughout the spinal cord and the hindbrain. Mutations ROBO3 result in horizontal gaze palsy with progressive scoliosis (HGPPS)\; an autosomal recessive disorder characterized by congenital absence of horizontal gaze, progressive scoliosis, and failure of the corticospinal and somatosensory axon tracts to cross the midline in the medulla. Alternative transcript variants have been described but have not been experimentally validated.

Genbezeichner und Symbole assoziert mit ROBO3

  • roundabout, axon guidance receptor, homolog 3 (Drosophila) (ROBO3) Antikörper
  • robo3 (robo3) Antikörper
  • roundabout, axon guidance receptor, homolog 3 (Drosophila) (Robo3) Antikörper
  • robo3 (TcasGA2_TC006743) Antikörper
  • roundabout 3 (robo3) Antikörper
  • roundabout homolog 3 (Drosophila) (Robo3) Antikörper
  • roundabout, axon guidance receptor, homolog 3 (LOC515936) Antikörper
  • CG5423 Antikörper
  • CG14345 Antikörper
  • CT17158 Antikörper
  • DKFZp468G0223 Antikörper
  • DmelCG5423 Antikörper
  • dRobo-3 Antikörper
  • HGPPS Antikörper
  • HGPS Antikörper
  • Rbig1 Antikörper
  • Rig-1 Antikörper
  • Rig1 Antikörper
  • Robo-3 Antikörper
  • robo3 Antikörper
  • Robo3a Antikörper
  • Robo3b Antikörper

Bezeichner auf Proteinebene für ROBO3

retinoblastoma inhibiting gene 1 , roundabout homolog 3 , roundabout-like protein 3 , robo3 , CG5423-PA , robo3-PA , roundabout, axon guidance receptor, homolog 3 , roundabout, axon guidance receptor, homolog 3 (Drosophila) , GLEAN_06743 , roundabout 3 , roundabout homolog 3-like , retinoblastoma-inhibiting gene 1 protein

GENE ID SPEZIES
64221 Homo sapiens
33314 Drosophila melanogaster
315564 Rattus norvegicus
466839 Pan troglodytes
489307 Canis lupus familiaris
658818 Tribolium castaneum
716274 Macaca mulatta
100072287 Equus caballus
100172083 Pongo abelii
100322880 Xenopus laevis
100342258 Oryctolagus cuniculus
100403106 Callithrix jacchus
100524637 Sus scrofa
100588193 Nomascus leucogenys
19649 Mus musculus
515936 Bos taurus
100858578 Gallus gallus
100337359 Bos taurus
Ausgewählte Anbieter für anti-ROBO3 (ROBO3) Antikörper
Haben Sie etwas anderes gesucht?