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Bilateral symmetric nervous systems have special midline structures that establish a partition between the two mirror image halves. Zusätzlich bieten wir Ihnen ROBO1 Proteine (9) und ROBO1 Kits (5) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 98 products:
Dog (Canine) Polyclonal ROBO1 Primary Antibody für EIA, IHC (p) - ABIN401279
Latil, Chêne, Cochant-Priollet, Mangin, Fournier, Berthon, Cussenot: Quantification of expression of netrins, slits and their receptors in human prostate tumors. in International journal of cancer. Journal international du cancer 2002
Zeige alle 6 Referenzen für ABIN401279
Human Polyclonal ROBO1 Primary Antibody für IP, IHC - ABIN1043879
Li, Wang, Chen, Liang: [Auditory neuropathy in children(analysis of 14 cases)]. in Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology 2005
Human Polyclonal ROBO1 Primary Antibody für ELISA, WB - ABIN251549
Hannula-Jouppi, Kaminen-Ahola, Taipale, Eklund, Nopola-Hemmi, Kääriäinen, Kere: The axon guidance receptor gene ROBO1 is a candidate gene for developmental dyslexia. in PLoS genetics 2005
Human Polyclonal ROBO1 Primary Antibody für WB - ABIN265227
Dallol, Forgacs, Martinez, Sekido, Walker, Kishida, Rabbitts, Maher, Minna, Latif: Tumour specific promoter region methylation of the human homologue of the Drosophila Roundabout gene DUTT1 (ROBO1) in human cancers. in Oncogene 2002
Mouse (Murine) Polyclonal ROBO1 Primary Antibody für ELISA, WB - ABIN185724
Andrews, Liapi, Plachez, Camurri, Zhang, Mori, Murakami, Parnavelas, Sundaresan, Richards: Robo1 regulates the development of major axon tracts and interneuron migration in the forebrain. in Development (Cambridge, England) 2006
These results demonstrate a key role for Robo-Slit signaling in vertebrate longitudinal axon guidance; Robo1 and Robo3 (zeige ROBO3 Antikörper) restricted the extent of defasciculation of the tract of the postoptic commissure.
restoration of miR (zeige MLXIP Antikörper)-218 inhibited retinal angiogenesis via targeting Robo1. MiR (zeige MLXIP Antikörper)-218 contributed to the inhibition of retinal angiogenesis and miR (zeige MLXIP Antikörper)-218 might be a new therapeutic target for preventing retinal neovascularization..
In mice with oxygen-induced retinopathy (OIR), the expression level of miR-218 was significantly downregulated. Robo1 expression was suppressed by miR-218. Furthermore, in the mice with OIR, the expression level of miR-218 was significantly downregulated, and that of miR-218-1 and its host gene, Slit2, was concomitantly downregulated as well.
Robo1-Slit2 interaction required for pathfinding mechanism essential to establish the functionally important habenulo-interpeduncular connection.
FLRT3 (zeige FLRT3 Antikörper) is a Robo1 coreceptor in developing axons.
Slit2 (zeige SLIT2 Antikörper)/Robo1 signaling promotes intestinal tumorigenesis through Src (zeige SRC Antikörper)-mediated activation of the Wnt (zeige WNT2 Antikörper)/beta-catenin (zeige CTNNB1 Antikörper) pathway.
Robo1/2 regulate follicle atresia through manipulating granulosa cell apoptosis in mice
Roundabout receptor (Robo) genes are expressed in pulmonary neuroendocrine cells (PNECs), a rare, innervated epithelial population. Robo inactivation in mouse lung results in an inability of PNECs to cluster into sensory organoids and triggers increased neuropeptide production upon exposure to air.
Slit2 (zeige SLIT2 Antikörper) signaling through Robo1 and Robo2 (zeige ROBO2 Antikörper) has a role in retinal neovascularization
Data indicate the roles of Slit1 (zeige SLIT1 Antikörper)/Robo1 and Netrin1/DCC (zeige DCC Antikörper) signals in positioning motor neuron cell bodies.
This study demonistrated that significant increase of interneurons in the cortices of Robo1-/- mice, implicate Robo1 in the regulation of progenitor cell dynamics in the developing forebrain.
Over-expression of miR (zeige MLXIP Antikörper)-218 in glioma cells may inhibit the proliferation and tumorigenicity through targeting Robo1, suggesting that miR (zeige MLXIP Antikörper)-218 could be a potential target for developing therapies in treating glioma.
Significantly increased serum Slit2 (zeige SLIT3 Antikörper) levels and hepatic expression of Slit2 (zeige SLIT3 Antikörper) and Robo1 were observed in patients with liver fibrosis.
our findings indicated that Slit2 (zeige SLIT3 Antikörper)/Robo1 axis possibly be regarded as a significant clinical parameter for predicting brain metastasis in breast cancer patients.
miR (zeige MLXIP Antikörper)-29a markedly inhibits the protein expression of Robo1 in mesenchymal stem cells.
A SLIT2 (zeige SLIT3 Antikörper)/ROBO1 signaling circuit as a key regulatory mechanism.
These results suggest that Slit2 (zeige SLIT3 Antikörper)/Robo1 binding exerts an effect on cell migration, which is negatively regulated by Robo4 (zeige ROBO4 Antikörper), and Robo1 may function by interacting with CdGAP (zeige ARHGAP31 Antikörper) in HUVECs.
ROBO1 somatic mutation is associated with myelodysplastic syndrome progression. Overexpression of ROBO1 produces anti-proliferative and pro-apoptotic effects in leukaemia cells. However, this effect was lost in ROBO mutants.
Robo1 promoted cell division cycle 42 (Cdc42 (zeige CDC42 Antikörper)) expression in HUVECs, and a distorted actin cytoskeleton in HUVECs was observed when Robo1 expression was suppressed. In conclusion, Robo1 promoted angiogenesis in HCC (zeige FAM126A Antikörper) mediated by Cdc42 (zeige CDC42 Antikörper).
Data indicate that SLIT2 (zeige SLIT3 Antikörper), miR (zeige MLXIP Antikörper)-218-1, RET (zeige RET Antikörper)/PLAG1 (zeige PLAG1 Antikörper) and SLIT2 (zeige SLIT3 Antikörper)/ROBO1 pathway involved in Hirschsprung's disease.
these studies demonstrate that miR (zeige MLXIP Antikörper)-219-5p inhibited cancer cell growth and invasion by direct targeting ROBO1, implicating miR (zeige MLXIP Antikörper)-219-5p as an attractive candidate for cancer therapy.
Bilateral symmetric nervous systems have special midline structures that establish a partition between the two mirror image halves. Some axons project toward and across the midline in response to long-range chemoattractants emanating from the midline. The product of this gene is a member of the immunoglobulin gene superfamily and encodes an integral membrane protein that functions in axon guidance and neuronal precursor cell migration. This receptor is activated by SLIT-family proteins, resulting in a repulsive effect on glioma cell guidance in the developing brain. A related gene is located at an adjacent region on chromosome 3. Multiple transcript variants encoding different isoforms have been found for this gene.
roundabout (axon guidance receptor, Drosophila) homolog 1
, roundabout, axon guidance receptor, homolog 1 (Drosophila)
, Roundabout1 protein
, roundabout 1
, roundabout homolog 1
, roundabout, axon guidance receptor, homolog 1
, roundabout homolog 1-like
, divalent metal transporter-1
, protein RoBo-1
, rodent bone protein
, deleted in U twenty twenty