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Ring Finger Protein 125 Proteine (RNF125)

RNF125 encodes a novel E3 ubiquitin ligase that contains a RING finger domain in the N-terminus and three zinc-binding and one ubiquitin-interacting motif in the C-terminus. Zusätzlich bieten wir Ihnen RNF125 Antikörper (53) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
RNF125 67664 Q9D9R0
Ratte RNF125 RNF125 361296  
RNF125 54941 Q96EQ8
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Showing 4 out of 4 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
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Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
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HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
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Hefe Macaca fascicularis His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.458,41 €
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RNF125 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine)

Human ,
,

Weitere Proteine zu Ring Finger Protein 125 (RNF125) Interaktionspartnern

Mouse (Murine) Ring Finger Protein 125 (RNF125) Interaktionspartner

  1. Data indicate that brain from Japanese encephalitis virus (JEV)-infection showed a reciprocal correlation between microRNA miR-15b levels and the ex (zeige MLXIP Proteine)pression of ring finger protein 125 (RNF125).

  2. RNF125 is enhanced by IFN, these functions constitute a negative regulatory loop circuit for IFN production

Human Ring Finger Protein 125 (RNF125) Interaktionspartner

  1. we identified the downregulation of the ubiquitin ligase RNF125 in BRAFi-resistant melanomas

  2. Results indicate that the nucleotide sequence in the 3' untranslated region (3' UTR) of ring finger protein 125 (RNF125) is a potential microRNA miR (zeige MLXIP Proteine)-15b targeting site.

  3. studies of the RNF125 pathway point to upregulation of RIG-I (zeige DDX58 Proteine)-IPS1 (zeige MAVS Proteine)-MDA5 (zeige IFIH1 Proteine) and/or disruption of the PI3K (zeige PIK3CA Proteine)-AKT (zeige AKT1 Proteine) and interferon (zeige IFNA Proteine) signaling pathways as the putative final effectors

  4. In controls, RNF125 is the highest expressed gene, whereas in HIV infection progressors, RIG-I (zeige DDX58 Proteine) is either the highest expressed gene or is expressed similarly to RNF125 and TRIM25 (zeige TRIM25 Proteine).

  5. study reports human bocavirus VP2 modulates IFN pathway by targeting the ring finger protein 125, a negative regulator of type I IFN signaling, which conjugates Lys (zeige LYZ Proteine)(48)-linked ubiquitination to retinoic acid-inducible gene-I (zeige DDX58 Proteine) and leads to the proteasome-dependent degradation of RIG-I (zeige DDX58 Proteine)

  6. These results suggest that RNF125/TRAC-1 could function to recruit host factor(s) controlling HIV-1 transcription to the ubiquitin-proteasome pathway.

  7. TRAC-1 associates with membranes and is excluded from the nucleus through myristoylation

RNF125 Protein Überblick

Protein Überblick

This gene encodes a novel E3 ubiquitin ligase that contains a RING finger domain in the N-terminus and three zinc-binding and one ubiquitin-interacting motif in the C-terminus. As a result of myristoylation, this protein associates with membranes and is primarily localized to intracellular membrane systems. The encoded protein may function as a positive regulator in the T-cell receptor signaling pathway.

Genbezeichner und Symbole assoziert mit RNF125

  • ring finger protein 125 (RNF125)
  • ring finger protein 125 (Rnf125)
  • ring finger protein 125, E3 ubiquitin protein ligase (RNF125)
  • 4930553F04Rik Protein
  • TRAC-1 Protein
  • TRAC1 Protein

Bezeichner auf Proteinebene für RNF125

E3 ubiquitin-protein ligase RNF125 , T-cell RING activation protein 1 , T-cell ring protein identified in activation screen

GENE ID SPEZIES
519541 Bos taurus
67664 Mus musculus
361296 Rattus norvegicus
54941 Homo sapiens
743809 Pan troglodytes
490498 Canis lupus familiaris
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