anti-Ring Finger Protein 111 (RNF111) Antikörper

The protein encoded by RNF111 is a nuclear RING-domain containing E3 ubiquitin ligase. Zusätzlich bieten wir Ihnen RNF111 Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
RNF111 93836 Q99ML9
RNF111 54778 Q6ZNA4
RNF111 300813  
Direkt bei antikoerper-online bestellen
  • +49 (0)241 95 163 153
  • +49 (0)241 95 163 155
  • Online bestellen
  • orders@antikoerper-online.de

Top anti-RNF111 Antikörper auf antikoerper-online.de

Showing 10 out of 36 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 6 bis 8 Tage
342,86 €
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p) Immunocytochemistry/Immunofluorescence: RNF111 Antibody [NBP1-94139] Staining of human cell line U-2 OS shows positivity in nucleus but not nucleoli & cytoplasm. Immunohistochemistry-Paraffin: RNF111 Antibody [NBP1-94139] - Staining of human kidney shows strong cytoplasmic positivity in cells in tubules. 0.1 mL Anmelden zum Anzeigen 5 bis 8 Tage
335,00 €
Details
Human Maus Unkonjugiert IF, RNAi, ELISA, WB Western blot analysis of RNF111 over-expressed 293 cell line, cotransfected with RNF111 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with RNF111 monoclonal antibody (M05), clone 1C4. GAPDH ( 36.1 kDa ) used as specificity and loading control. Western Blot analysis of RNF111 expression in transfected 293T cell line by RNF111 monoclonal antibody (M05), clone 1C4.<br><br>Lane 1: RNF111 transfected lysate(107.8 KDa).<br>Lane 2: Non-transfected lysate.<br> 100 μg Anmelden zum Anzeigen 7 bis 8 Tage
369,60 €
Details
Human Kaninchen Unkonjugiert WB RNF111 Antibody (N-term)  western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the RNF111 antibody detected the RNF111 protein (arrow). 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Maus Unkonjugiert IHC (p), WB Western Blot analysis of RNF111 expression in transfected 293T cell line by RNF111 MaxPab polyclonal antibody.<br><br>Lane 1: RNF111 transfected lysate(108.35 KDa).<br>Lane 2: Non-transfected lysate.<br> RNF111 MaxPab polyclonal antibody. Western Blot analysis of RNF111 expression in rat brain. 50 μg Anmelden zum Anzeigen 7 bis 8 Tage
369,60 €
Details
Human Maus Unkonjugiert WB Western blot analysis of RNF111 over-expressed 293 cell line, cotransfected with RNF111 Validated Chimera RNAi used as specificity and loading control. Western Blot analysis of RNF111 expression in transfected 293T cell line by RNF111 monoclonal antibody (M05), clone 1C4. Lane 1: RNF111 transfected lysate(107.8 KDa). Lane 2: Non-transfected lysate. 0.1 mg Anmelden zum Anzeigen 12 bis 16 Tage
454,76 €
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: RNF111 Antibody [NBP1-94140] - Immunohistochemical staining of human kidney shows strong cytoplasmic and membranous positivity in cells in tubules. Western Blot: RNF111 Antibody [NBP1-94140] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells). Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells). 0.1 mL Anmelden zum Anzeigen 5 bis 8 Tage
335,00 €
Details
Human Kaninchen Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 6 bis 8 Tage
342,86 €
Details
Human Kaninchen Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 6 bis 8 Tage
398,93 €
Details
Human Kaninchen Unkonjugiert IHC, WB   50 μg Anmelden zum Anzeigen 6 bis 8 Tage
460,89 €
Details

RNF111 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Mouse (Murine)


Human ,
,
,
, , , , ,
Rat (Rattus)


Am meisten referenzierte anti-RNF111 Antikörper

  1. Human Monoclonal RNF111 Primary Antibody für IF, RNAi - ABIN527194 : Levy, Howell, Das, Harkin, Episkopou, Hill: Arkadia activates Smad3/Smad4-dependent transcription by triggering signal-induced SnoN degradation. in Molecular and cellular biology 2007 (PubMed)
    Show all 9 Pubmed References

  2. Human Polyclonal RNF111 Primary Antibody für IHC (p), WB - ABIN527193 : Zhou, Drabsch, Dekker, de Vinuesa, Li, Hawinkels, Sheppard, Goumans, Luwor, de Vries, Mesker, Tollenaar, Devilee, Lu, Zhu, Zhang, Dijke: Nuclear receptor NR4A1 promotes breast cancer invasion and metastasis by activating TGF-? signalling. in Nature communications 2014 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal RNF111 Primary Antibody für ICC, IF - ABIN4350718 : Mizutani, Koinuma, Seimiya, Miyazono: The Arkadia-ESRP2 axis suppresses tumor progression: analyses in clear-cell renal cell carcinoma. in Oncogene 2016 (PubMed)

Weitere Antikörper gegen RNF111 Interaktionspartner

Mouse (Murine) Ring Finger Protein 111 (RNF111) Interaktionspartner

  1. Arkadia, but not the C937A (CA) mutant lacking E3 ubiquitin-ligase (zeige MUL1 Antikörper) activity, induced ubiquitylation and proteasome-dependent degradation of Smad6 (zeige SMAD6 Antikörper).

  2. Arkadia enhances transforming growth factor-beta signaling responses and supports its tumor-suppressing properties in colorectal cancer.

  3. RB1CC1 (zeige RB1CC1 Antikörper) thus appears to play a unique role as a modulator of TGF-beta (zeige TGFB1 Antikörper) signaling by restricting substrate specificity of Arkadia.

  4. Trps1 haploinsufficiency enhances TGF-beta1-induced epithelial-to-mesenchymal transition (EMT) and tubulointerstitial fibrosis by modulating the amount of Smad7 through Arkadia/ubiquitin-mediated degradation.

  5. findings show that Arkadia regulates the levels of expression of c-Ski (zeige SKI Antikörper) protein (zeige SKIL Antikörper) in cell-type-dependent fashion, and exhibits a tumour suppressor function by inhibiting tumour cell growth

  6. Axin (zeige AXIN1 Antikörper) and Arkadia cooperate with each other in promoting Smad7 (zeige SMAD7 Antikörper) ubiquitination.

  7. Arkadia, a nuclear RING-domain E3 ubiquitin ligase (zeige MUL1 Antikörper), is essential for a subset of Nodal functions in the embryo

  8. Arkadia induces degradation of SnoN (zeige SKIL Antikörper) and c-Ski (zeige SKI Antikörper) in addition to Smad7 (zeige SMAD7 Antikörper).

  9. These results suggest that Arkadia targets Ski (zeige SKI Antikörper)-bound, inactive phospho-Smad2 (zeige SMAD2 Antikörper)/3 to regulate positively Myostatin (zeige MSTN Antikörper)/TGF-beta (zeige TGFB1 Antikörper) signaling.

  10. This work presents an efficient method for expression in E. coli and purification of recombinant Arkadia RING finger (zeige PCGF1 Antikörper) domain as a soluble protein.

Human Ring Finger Protein 111 (RNF111) Interaktionspartner

  1. Results indicate a tumor-suppressive role of the ring finger protein 111 (Arkadia)-epithelial splicing regulatory protein 2 (ESRP2 (zeige ESRP2 Antikörper)) axis in clear-cell renal cell carcinoma (zeige MOK Antikörper) (ccRCC).

  2. These data show that the position occupied by W972 within wild-type Arkadia is critical for the function of its RING domain and that it depends on the nature of the residue at this position.

  3. Results suggest that -459CpG methylation in Sp1 (zeige PSG1 Antikörper)-binding site of RNF111 promoter transcriptionally decreases RNF111 expression, which inhibits TGF-beta (zeige TGFB1 Antikörper)/Smad (zeige SMAD1 Antikörper) signaling associated invasion in NSCLC cells.

  4. Study reports that the monomeric RING domains from the human E3 ligases Arkadia and Ark2C bind directly to free ubiquitin with an affinity comparable to that of other dedicated ubiquitin-binding domains.

  5. These data suggest that RNF111, together with the CRL4(DDB2 (zeige DDB2 Antikörper)) ubiquitin ligase complex, is responsible for sequential XPC (zeige XPC Antikörper) ubiquitylation, which regulates the recruitment and release of XPC (zeige XPC Antikörper) and is crucial for efficient progression of the NER (zeige NR1H2 Antikörper) reaction.

  6. Arkadia can both promote and inhibit gene expression, indicating that Arkadia's activity in transcriptional control may depend on the epigenetic context, defined by Polycomb (zeige CBX2 Antikörper) repressive complexes and DNA methylation (zeige HELLS Antikörper).

  7. Our findings establish RNF111 as a new STUbL that directly links nonproteolytic ubiquitylation and SUMOylation in the DNA damage response.

  8. findings indicate that Arkadia is not critical for regulating tumor growth per se, but is required for the early stages of cancer cell colonization at the sites of metastasis

  9. Arkadia is involved in arsenic-induced degradation of polysumoylated PML (zeige PML Antikörper) protein.

  10. RNF111-dependent neddylation activates DNA damage-induced ubiquitination

RNF111 Antigen-Profil

Protein Überblick

The protein encoded by this gene is a nuclear RING-domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) -beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription. As a modulator of the nodal signaling cascade, this gene plays a critical role in the induction of mesoderm during embryonic development. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.

Genbezeichner und Symbole assoziert mit RNF111

  • ring finger protein 111 (RNF111) Antikörper
  • hypothetical LOC702104 (RNF111) Antikörper
  • ring finger protein 111 (rnf111) Antikörper
  • ring finger protein 111 (LOC100222518) Antikörper
  • ring finger protein 111 (LOC100357930) Antikörper
  • ring finger 111 (Rnf111) Antikörper
  • ring finger protein 111 (Rnf111) Antikörper
  • ark Antikörper
  • Arkadia Antikörper
  • MGC81253 Antikörper
  • MGC146379 Antikörper
  • RNF111 Antikörper

Bezeichner auf Proteinebene für RNF111

E3 ubiquitin-protein ligase Arkadia , arkadia , hypothetical LOC702104 , ring finger protein 111 , e3 ubiquitin-protein ligase Arkadia-like , RING finger protein 111 , Arkadia , ring finger 111

GENE ID SPEZIES
540353 Bos taurus
374021 Gallus gallus
478323 Canis lupus familiaris
100155446 Sus scrofa
702104 Macaca mulatta
453477 Pan troglodytes
701953 Macaca mulatta
780266 Xenopus (Silurana) tropicalis
100054463 Equus caballus
100222518 Taeniopygia guttata
100357930 Oryctolagus cuniculus
100475090 Ailuropoda melanoleuca
100543062 Meleagris gallopavo
100555431 Anolis carolinensis
100579843 Nomascus leucogenys
93836 Mus musculus
54778 Homo sapiens
300813 Rattus norvegicus
Ausgewählte Anbieter für anti-RNF111 (RNF111) Antikörper
Haben Sie etwas anderes gesucht?