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Ribonuclease H1 Proteine (RNASEH1)

Endonuclease that specifically degrades the RNA of RNA- DNA hybrids.. Zusätzlich bieten wir Ihnen Ribonuclease H1 Antikörper (27) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
RNASEH1 19819  
RNASEH1 298933 Q5BK46
RNASEH1 246243 O60930
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Top Ribonuclease H1 Proteine auf antikoerper-online.de

Showing 5 out of 6 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
Details
HOST_Wheat germ Human GST tag 2 μg Anmelden zum Anzeigen 7 bis 8 Tage
235,20 €
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Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.619,05 €
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HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 6 bis 8 Tage
748,00 €
Details

RNASEH1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine)

Rat (Rattus)

Human , ,
, ,

Weitere Proteine zu Ribonuclease H1 (RNASEH1) Interaktionspartnern

Mouse (Murine) Ribonuclease H1 (RNASEH1) Interaktionspartner

  1. RNase H1 is necessary for the activity of DNA-like ASOs. During liver regeneration, a clone of hepatocytes that expressed RNase H1 developed and partially restored mitochondrial and liver function.

  2. the essential role of RNase H1 in mitochondrial DNA replication is the removal of primers at the origin of replication

  3. translational organization of RNase H1 allows tight control of expression of RNase H1 in mitochondria, where its excess or absence can lead to cell death, without affecting the expression of the nuclear RNase H1

  4. RNase H1 is involved in generation of mitochondrial DNA

Human Ribonuclease H1 (RNASEH1) Interaktionspartner

  1. RNaseH1 maintains regulated levels of telomeric RNA-DNA hybrids at ALT telomeres to trigger homologous recombination without compromising telomere integrity too severely

  2. found that the 3' fragments of target pre-mRNA generated by ASO were almost completely degraded from their 5' ends by nuclear XRN2 (zeige XRN2 Proteine) after RNase H1-mediated cleavage

  3. Altered RNaseH1 has a reduced capability to remove the RNA from RNA-DNA hybrids leading to impaired mtDNA replication and adult-onset mitochondrial encephalomyopathy.

  4. RNase H1 and protein P32 are involved in mitochondrial pre-rRNA processing

  5. data implicate the H264 side chain in phosphodiester hydrolysis as well as in product release, and are consistent with a proposed model in which the RNAse H1 H264 side chain interacts with a divalent metal ion to support catalysis

  6. On the basis of its nuclear magnetic resonance (NMR) nucleic acid structure, a boranophosphonate-modified, fully R(P) BH(3) DNA/RNA hybrid is predicted not to be a substrate for RNase H1.

  7. The cysteine residues responsible for the redox-dependent activity of RNase H1 were determined by site-directed mutagenesis to involve Cys (zeige DNAJC5 Proteine)(147) and Cys (zeige DNAJC5 Proteine)(148), producing an inactive enzyme conformation by disulfide bond formation.

  8. Human RNase H1 uses one tryptophan and two lysines to position the enzyme at the 3'-DNA/5'-RNA terminus of the heteroduplex substrate

  9. in human cells RNase H1 is responsible for most of the activity of DNA-like antisense drugs

  10. analysis of catalytic site of human RNase H1 for heteroduplex substrate catalysis

Ribonuclease H1 (RNASEH1) Protein Überblick

Protein Überblick

Endonuclease that specifically degrades the RNA of RNA- DNA hybrids.

Genbezeichner und Symbole assoziert mit Ribonuclease H1 Proteine (RNASEH1)

  • ribonuclease H1 (rnh1)
  • ribonuclease H1 (rnaseh1-b)
  • similar to Ribonuclease H1 (RNase H1) (Ribonuclease H type II) (RNASEH1)
  • ribonuclease H1 (RNASEH1)
  • ribonuclease H1 (rnaseh1-a)
  • ribonuclease H1 (AFUA_1G10020)
  • ribonuclease H1 (Tb927.7.4930)
  • ribonuclease H1 (rnhA)
  • ribonuclease H1 (rnaseh1)
  • Ribonuclease H1 (rnh1)
  • ribonuclease H1 (Rnaseh1)
  • ribonuclease H1 pseudogene 1 (RNASEH1P1)
  • 74/9 Protein
  • Afu1g10020 Protein
  • CG8729 Protein
  • Dmel\\CG8729 Protein
  • H1RNA Protein
  • l(2)43F1-5 Protein
  • l(2)43Fa Protein
  • l(2)k07409 Protein
  • l(2)k07624 Protein
  • RNase H1 Protein
  • rnaseh1 Protein
  • RNASEH1P Protein
  • RNASEH1P1 Protein
  • RNH1 Protein
  • rnhl Protein
  • Tb07.26A24.40 Protein
  • zgc:91971 Protein

Bezeichner auf Proteinebene für Ribonuclease H1 Proteine (RNASEH1)

CG8729-PA , CG8729-PB , RNaseH1 , rnh1-PA , rnh1-PB , ribonuclease H1 , ribonuclease H1 pseudogene 1 , Ribonuclease H1 , RNase H1 , ribonuclease H type II

GENE ID SPEZIES
35746 Drosophila melanogaster
414644 Xenopus laevis
696333 Macaca mulatta
707122 Macaca mulatta
735129 Xenopus laevis
743012 Pan troglodytes
3510641 Aspergillus fumigatus Af293
3658705 Trypanosoma brucei brucei strain 927/4 GUTat10.1
3930711 Anaplasma phagocytophilum str. HZ
100124876 Xenopus (Silurana) tropicalis
100196582 Salmo salar
100305327 Oncorhynchus mykiss
436932 Danio rerio
395848 Gallus gallus
475648 Canis lupus familiaris
613354 Bos taurus
19819 Mus musculus
298933 Rattus norvegicus
246243 Homo sapiens
284203 Homo sapiens
Ausgewählte Anbieter für Ribonuclease H1 Proteine (RNASEH1)
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