anti-Rhotekin (RTKN) Antikörper

RTKN encodes a scaffold protein that interacts with GTP-bound Rho proteins. Zusätzlich bieten wir Ihnen Rhotekin Proteine (8) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
RTKN 6242 Q9BST9
RTKN 20166 Q8C6B2
RTKN 297383 Q6V7V2
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Top anti-Rhotekin Antikörper auf antikoerper-online.de

Showing 10 out of 39 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-RTKN Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>Human Liver 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-RTKN Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>293T cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB Immunohistochemical analysis of Rhotekin staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of Rhotekin expression in HeLa (A), Raw264.7 (B), PC12 (C) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert WB Western Blot: RTKN Antibody [NBP1-54973] - Titration: 0.2-1 ug/ml, Positive Control: Human Liver. 100 μL Anmelden zum Anzeigen 8 bis 11 Tage
$447.56
Details
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Maus Unkonjugiert IHC, WB Western Blot: RTKN Antibody (2E9) [NBP2-45966] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RTKN. 0.1 mL Anmelden zum Anzeigen 8 bis 11 Tage
$513.19
Details
Human Kaninchen Unkonjugiert ICC, IF, WB Western Blot: RTKN Antibody [NBP2-20239] - Sample (20 ug of whole cell lysate) A: mouse brain 7. 5% SDS PAGE gel, diluted at 1:10000. Western Blot: RTKN Antibody [NBP2-20239] - Sample (30 ug of whole cell lysate) A: JurKat 7. 5% SDS PAGE gel, diluted at 1:1000. 0.1 mL Anmelden zum Anzeigen 8 bis 11 Tage
$447.56
Details
Human Maus Unkonjugiert WB RTKN monoclonal antibody (M01), clone 2E5 Western Blot analysis of RTKN expression in A-431 on formalin-fixed paraffin-embedded human colon (antibody concentration 3 µg/mL). 0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$450.00
Details
Human Kaninchen Unkonjugiert WB Rhotekin antibody used at 1 ug/ml to detect target protein. 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$473.93
Details

RTKN Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
Human ,
,
,
Mouse (Murine) ,


Rat (Rattus) ,


Am meisten referenzierte anti-Rhotekin Antikörper

  1. Human Polyclonal Rhotekin Primary Antibody für WB - ABIN4890447 : Pusapati, Eiseler, Rykx, Vandoninck, Derua, Waelkens, Van Lint, von Wichert, Seufferlein: Protein kinase D regulates RhoA activity via rhotekin phosphorylation. in The Journal of biological chemistry 2012 (PubMed)

Weitere Antikörper gegen Rhotekin Interaktionspartner

Human Rhotekin (RTKN) Interaktionspartner

  1. Let-7a microRNA inhibits tumor cell growth and metastasis by directly targeting RTKN in human colon cancer.

  2. RTKN is upregulated in hepatocellular carcinoma.MicroRNA-152 inhibits tumor cell growth by directly targeting RTKN in hepatocellular carcinoma.

  3. The RTKN protein is associated with lung cancer in clinic samples and exerts anticancer activity in lung adenocarcinoma cells through inhibiting cell cycle progression and the DNA replication machinery.

  4. RTKN could affect the proliferation and metastasis of colon cancer by reducing expression of MCM2 (zeige MCM2 Antikörper)/3/5, CDK1 (zeige CDK1 Antikörper)/2 and PCNA (zeige PCNA Antikörper)

  5. suggest that interaction of S100A4 (zeige S100A4 Antikörper) and Rhotekin permits S100A4 (zeige S100A4 Antikörper) to complex with RhoA (zeige RHOA Antikörper) and switch Rho function from stress fiber formation to membrane ruffling to confer an invasive phenotypea

  6. Protein kinase D (zeige PRKD1 Antikörper) regulates RhoA (zeige RHOA Antikörper) activity via phosphorylation rhotekin at Ser (zeige SIGLEC1 Antikörper)-435.

  7. Rho/RTKN-mediated NF-kappaB (zeige NFKB1 Antikörper) activation leading to cell survival may play a key role in gastric tumorigenesis.

  8. These results suggest that the RTKN gene is involved in bladder carcinogenesis and progression in bladder carcinoma, indicating that RTKN gene could be a molecular target in cancer therapy.

  9. Lin-7B (zeige LIN7B Antikörper) is a binding partner for Rhotekin in the human brain cDNA library

  10. SEPT9 (zeige SEPT9 Antikörper) sequence alternations causing hereditary neuralgic amyotrophy are associated with altered interactions with SEPT4 (zeige SEPT4 Antikörper)/SEPT11 (zeige SEPT11 Antikörper) and resistance to Rho/Rhotekin-signaling

Mouse (Murine) Rhotekin (RTKN) Interaktionspartner

  1. these findings suggest that cGK (zeige PRKG1 Antikörper)-Ialpha interacts with and phosphorylates rhotekin, thereby contributing to neurite outgrowth regulation.

Rhotekin (RTKN) Antigen-Profil

Protein Überblick

This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.

Genbezeichner und Symbole assoziert mit anti-Rhotekin (RTKN) Antikörper

  • rhotekin (RTKN) Antikörper
  • rhotekin (rtkn) Antikörper
  • rhotekin (Rtkn) Antikörper
  • RTKN Antikörper

Bezeichner auf Proteinebene für anti-Rhotekin (RTKN) Antikörper

rhotekin , rhotekin-like

GENE ID SPEZIES
459334 Pan troglodytes
100053888 Equus caballus
100124981 Xenopus (Silurana) tropicalis
100349385 Oryctolagus cuniculus
100400941 Callithrix jacchus
100455723 Pongo abelii
100474465 Ailuropoda melanoleuca
100519086 Sus scrofa
6242 Homo sapiens
20166 Mus musculus
297383 Rattus norvegicus
475788 Canis lupus familiaris
539691 Bos taurus
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