Retinol Binding Protein 1, Cellular Proteine (RBP1)

RBP1 encodes the carrier protein involved in the transport of retinol (vitamin A alcohol) from the liver storage site to peripheral tissue. Zusätzlich bieten wir Ihnen Retinol Binding Protein 1, Cellular Antikörper (61) und Retinol Binding Protein 1, Cellular Kits (23) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
RBP1 5947 P09455
RBP1 19659 Q00915
RBP1 25056 P02696
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Showing 10 out of 16 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 6 bis 8 Tage
748,00 €
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HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
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HOST_Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
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HOST_Escherichia coli (E. coli) Human His tag 50 μg Anmelden zum Anzeigen 11 bis 15 Tage
303,81 €
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HOST_Escherichia coli (E. coli) Rind (Kuh) His tag 100 μg Anmelden zum Anzeigen 13 bis 17 Tage
670,48 €
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HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
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Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.172,07 €
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Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.172,07 €
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HOST_Escherichia coli (E. coli) Human Unkonjugiert   10 μg Anmelden zum Anzeigen 8 bis 9 Tage
231,00 €
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HOST_Escherichia coli (E. coli) Wildschwein His tag   100 μg Anmelden zum Anzeigen 13 bis 17 Tage
579,05 €
Details

RBP1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine)

Rat (Rattus) ,

Am meisten referenzierte Retinol Binding Protein 1, Cellular Proteine

  1. Human RBP1 Protein expressed in Escherichia coli (E. coli) - ABIN667614 : Folli, Calderone, Ottonello, Bolchi, Zanotti, Stoppini, Berni: Identification, retinoid binding, and x-ray analysis of a human retinol-binding protein. in Proceedings of the National Academy of Sciences of the United States of America 2001 (PubMed)
    Zeige alle 2 Referenzen für 667614

  2. Human RBP1 Protein expressed in HEK-293 Cells - ABIN2730759 : Arnold, Kent, Hogarth, Schlatt, Prasad, Haenisch, Walsh, Muller, Griswold, Amory, Isoherranen: Importance of ALDH1A enzymes in determining human testicular retinoic acid concentrations. in Journal of lipid research 2015 (PubMed)

Weitere Proteine zu Retinol Binding Protein 1, Cellular (RBP1) Interaktionspartnern

Human Retinol Binding Protein 1, Cellular (RBP1) Interaktionspartner

  1. Low CRBP1 expression is associated with low radiation sensitivity in rectal cancer.

  2. This conformational flexibility of human apo (zeige C9orf3 Proteine)-CRBP1 facilitates interaction with the ligands, whereas the more rigid holoprotein structure protects the labile retinoid moiety during vitamin A transport.

  3. Hypermethylation of CRBP1 gene is associated with Epstein-Barr virus-associated gastric carcinomas.

  4. Further studies are needed to explore new therapeutic strategies aimed at restoring CRBP-1-mediated intracellular retinol trafficking and the meaning of CRBP-1 expression in cancer patients screening for a more personalized and efficacy retinoid therapy

  5. RBP1 expression was reduced in tissue and endometrial stromal cells derived from endometritis lesions versus eutopic endometruim in humans and mice.

  6. Functional hepatic stellate cells coexpressing both LRAT (zeige LRAT Proteine) and CRBP-1, that continue to maintain the ability to store vitamin A, contribute in part to the development of portal and parenchymal fibrogenesis in patients with viral hepatitis.

  7. Factors involved in the retinoid pathway, in particular upregulation of CRBP, CRABP1 (zeige CRABP1 Proteine) and CRABP2 (zeige CRABP2 Proteine), also showed differential expression in tumors with different histological subtypes

  8. CRBP-1 loss in G2/G3 ovarian carcinomas and increased apoptotic susceptibility to retinoids.

  9. Suggest CRBP1 gene as a tumor suppressor gene for cervical cancer.

  10. RBP1 promoter hypermethylation is found in nearly all IDH1 (zeige IDH1 Proteine) and IDH2 (zeige IDH2 Proteine) mutant gliomas Because RBP1 is involved in retinoic acid synthesis, results suggest that dysregltion of RA metabolism may contribute to glioma formation along the IDH1 (zeige IDH1 Proteine)/IDH2 (zeige IDH2 Proteine)-mutant pathway

Mouse (Murine) Retinol Binding Protein 1, Cellular (RBP1) Interaktionspartner

  1. RBP1 expression was reduced in tissue and endometrial stromal cells derived from endometritis lesions versus eutopic endometruim in humans and mice.

  2. CrbpI loss disrupts all-trans retinoic acid homeostasis in mammary tissue, resulting in microenvironmental defects similar to those observed at the early stages of tumorigenesis.

  3. glucose homeostasis and energy metabolism rely on Rbp1 expression and its moderation of pancreas retinol and of the autacoid 9-cis-retinoic acid.

  4. As such, the effects of RBP1 on these processes are mediated through both regulation of Runx2 (zeige RUNX2 Proteine) expression and transcriptional activity.

  5. CRBP-I is a cytosolic protein specifically expressed in preadipocytes that regulates adipocyte differentiation in part by affecting PPAR gamma (zeige PPARG Proteine) activity.

  6. This murine RBP (zeige RBP4 Proteine)-null model may have relevance to fetal development in human populations with inadequate retinoid intake.

  7. Crbp1-/- mice also exhibited increased metabolism of a dose of retinol into retinoic acid, and this increased metabolism was not observed in Crbp1-/-/Adh1 (zeige ADH1A Proteine)-/- mice

  8. Data show that while vitamin A-replete retinol binding protein (rbp)-cryptochrome(cry) 1- and 2-knockout mice are light responsive, vitamin A-depleted knockout mice lose most behavioral and molecular responses to light.

  9. Epigenetic silencing of cellular CRBPI is associated with nasopharyngeal carcinoma

Xenopus laevis Retinol Binding Protein 1, Cellular (RBP1) Interaktionspartner

  1. The localization of CRBP1 within the retina and its demonstrated role in modulating the proper folding of nascent outer segment membranes through retinoic acid further elucidates the role of these cells in directly influencing photoreceptor physiology.

Retinol Binding Protein 1, Cellular (RBP1) Protein Überblick

Protein Überblick

This gene encodes the carrier protein involved in the transport of retinol (vitamin A alcohol) from the liver storage site to peripheral tissue. Vitamin A is a fat-soluble vitamin necessary for growth, reproduction, differentiation of epithelial tissues, and vision. Multiple transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit RBP1

  • nicotinamide nucleotide adenylyltransferase 3 (NMNAT3)
  • receptor tyrosine kinase (ret1)
  • retinol binding protein 1, cellular (rbp1)
  • retinol binding protein 1, cellular (LOC100228240)
  • retinol binding protein 1, cellular (RBP1)
  • retinol binding protein 1, cellular (Rbp1)
  • retinol binding protein 1a, cellular (rbp1a)
  • cb465 Protein
  • CRABP-I Protein
  • CRABP1 Protein
  • Crbp Protein
  • CRBP1 Protein
  • CRBPI Protein
  • Rbp-1 Protein
  • rbp1 Protein
  • RBPC Protein
  • wu:fb75e07 Protein
  • zgc:73335 Protein

Bezeichner auf Proteinebene für RBP1

retinol binding protein 1, cellular , proto-oncogene tyrosine-protein kinase receptor Ret , Retinol-binding protein I, cellular , CRBP-I , cellular retinol-binding protein I , retinol-binding protein 1 , retinol-binding protein 1, cellular , mCRBPI , CRBP , cellular retinol binding protein 1

GENE ID SPEZIES
715667 Macaca mulatta
100196451 Salmo salar
100216164 Xenopus (Silurana) tropicalis
100228240 Taeniopygia guttata
5947 Homo sapiens
19659 Mus musculus
25056 Rattus norvegicus
414642 Xenopus laevis
477090 Canis lupus familiaris
100156666 Sus scrofa
537379 Bos taurus
171477 Danio rerio
424821 Gallus gallus
Ausgewählte Anbieter für Retinol Binding Protein 1, Cellular Proteine (RBP1)
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