Retinoblastoma Binding Protein 5 Proteine (RBBP5)

RBBP5 encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. Zusätzlich bieten wir Ihnen Retinoblastoma Binding Protein 5 Antikörper (68) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
RBBP5 5929 Q15291
RBBP5 213464 Q8BX09
Ratte RBBP5 RBBP5 304794  
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Showing 3 out of 4 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 56 Days
7.380,00 €
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Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 56 Days
7.380,00 €
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HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
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RBBP5 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
,
Mouse (Murine)

Weitere Proteine zu Retinoblastoma Binding Protein 5 (RBBP5) Interaktionspartnern

Human Retinoblastoma Binding Protein 5 (RBBP5) Interaktionspartner

  1. role of RBQ3 in the development of multiple myeloma

  2. This study demonstrated that RBQ3 might play an important role in glioma, and RBQ3 inhibitors might be novel anti-tumor agents.

  3. The identified components revealed factors involved in histone methylation and cell cycle control and include Ash2L (zeige ASH2L Proteine), RbBP5, WDR5 (zeige WDR5 Proteine), HCF-1 (zeige HCFC1 Proteine), DBC-1 (zeige DBC1 Proteine), and EMSY (zeige C11orf30 Proteine).

  4. Non active site mutations in the MLL1 SET domain render the protein defective for H3K4 dimethylation by the MLL1 core complex, which is associated with a loss of the ability of MLL1 to interact with WRAD or with the RbBP5/Ash2L (zeige ASH2L Proteine) heterodimer.

  5. Data indicate that MLL1 methylates Ash2L (zeige ASH2L Proteine) in the absence of histone H3 (zeige HIST3H3 Proteine), but only when assembled within a complex with WDR5 (zeige WDR5 Proteine) and RbBP5.

  6. structural and biochemical analyses reveal a basic surface on Ash2L (zeige ASH2L Proteine) as the RbBP5-binding interface, and this interface is crucial for both RbBP5 binding and MLL1 methyltransferase activity regulation

  7. Results show that Depletion of CHD8 enhances HOXA2 (zeige HOXA2 Proteine) expression and a loss of the WDR5 (zeige WDR5 Proteine)/Ash2L (zeige ASH2L Proteine)/RbBP5 subcomplex.

  8. analysis of menin's role as a tumor suppressor and binding sites of Rbbp5 and MLL1

Mouse (Murine) Retinoblastoma Binding Protein 5 (RBBP5) Interaktionspartner

  1. a phosphorylation switch on RbBP5 stimulates WRAD complex formation and significantly increases KMT2 (lysine [K] methyltransferase 2 (zeige DNMT1 Proteine)) enzyme methylation rates

  2. Characterization of a novel WDR5 (zeige WDR5 Proteine)-binding site that recruits RbBP5 through a conserved motif to enhance methylation of histone H3 (zeige HIST3H3 Proteine) lysine 4 by mixed lineage leukemia protein-1.

Retinoblastoma Binding Protein 5 (RBBP5) Protein Überblick

Protein Überblick

This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. The encoded protein binds directly to retinoblastoma protein, which regulates cell proliferation. It interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A-binding pocket B. Three alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.

Genbezeichner und Symbole assoziert mit RBBP5

  • retinoblastoma binding protein 5 (RBBP5)
  • retinoblastoma binding protein 5 (rbbp5)
  • retinoblastoma binding protein 5 (LOC100356995)
  • retinoblastoma binding protein 5 (Rbbp5)
  • 4933411J24Rik Protein
  • C330016J05 Protein
  • DKFZp469C191 Protein
  • MGC56078 Protein
  • MGC80141 Protein
  • MGC97793 Protein
  • RBBP5 Protein
  • RBQ3 Protein
  • SWD1 Protein
  • zgc:56078 Protein
  • zgc:85864 Protein

Bezeichner auf Proteinebene für RBBP5

retinoblastoma binding protein 5 , retinoblastoma-binding protein 5-like , RBBP-5 , SWD1, Set1c WD40 repeat protein, homolog , retinoblastoma-binding protein 5 , retinoblastoma-binding protein RBQ-3

GENE ID SPEZIES
100054708 Equus caballus
393215 Danio rerio
446510 Xenopus laevis
457665 Pan troglodytes
595072 Xenopus (Silurana) tropicalis
100173341 Pongo abelii
100356995 Oryctolagus cuniculus
100470847 Ailuropoda melanoleuca
100513301 Sus scrofa
100544888 Meleagris gallopavo
100566805 Anolis carolinensis
100597470 Nomascus leucogenys
5929 Homo sapiens
488568 Canis lupus familiaris
510455 Bos taurus
213464 Mus musculus
304794 Rattus norvegicus
419826 Gallus gallus
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